Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM250401
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
Ki
1.40±n/a nM
Citation
 Groebke Zbinden, K; Norcross, R; Pflieger, P Substituted benzamides US Patent  US10501411 Publication Date 12/10/2019 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TAAR1_RAT | Ta1 | Taar1 | Tar1 | Trace amine receptor 1 (TARR1) | Trace amine-associated receptor 1 | Trace amine-associated receptor 1 (TAAR1) | Trace amine-associated receptor1 | Trar1
Type:
Enzyme
Mol. Mass.:
38034.73
Organism:
Rattus norvegicus (Rat)
Description:
Q923Y9
Residue:
332
Sequence:
MHLCHNSANISHTNSNWSRDVRASLYSLISLIILTTLVGNLIVIISISHFKQLHTPTNWLLHSMAVVDFLLGCLVMPYSMVRTVEHCWYFGELFCKLHTSTDIMLSSASILHLAFISIDRYYAVCDPLRYKAKINLAAIFVMILISWSLPAVFAFGMIFLELNLEGVEELYHNQVFCLRGCFPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRANLQVGLEGESRAPQSKETKAAKTLGIMVGVFLLCWCPFFFCMVLDPFLGYVIPPTLNDTLNWFGYLNSAFNPMVYAFFYPWFRRALKMVLFGKIFQKDSSRSKLFL
  
Inhibitor
Name:
BDBM250401
Synonyms:
US10501411, Example 311 | US11697636, Example 311 | US9452980, 311
Type:
Small organic molecule
Emp. Form.:
C18H18F3N3O2
Mol. Mass.:
365.3496
SMILES:
FC(F)(F)c1ccc(NC(=O)Nc2ccc(cc2)[C@@H]2CNCCO2)cc1 |r|
Structure:
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