Reaction Details Report a problem with these data
Target
Fatty acid-binding protein, heart
Ligand
BDBM451163
Substrate
n/a
Meas. Tech.
Fluorescent Displacement Assay
IC50
280±n/a nM
Citation
 Fukunaga, K; Miyachi, H; Ishida, H; Ban, S Agent for treating synucleinopathy US Patent  US10709688 Publication Date 7/14/2020 
Target
Name:
Fatty acid-binding protein, heart
Synonyms:
FABP11 | FABP3 | FABPH_HUMAN | Fatty acid binding protein muscle | MDGI
Type:
PROTEIN
Mol. Mass.:
14858.36
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1463784
Residue:
133
Sequence:
MVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTFKNTEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHLQKWDGQETTLVRELIDGKLILTLTHGTAVCTRTYEKEA
  
Inhibitor
Name:
BDBM451163
Synonyms:
US10709688, Example 3 | US10709688, Ligand 3
Type:
Small organic molecule
Emp. Form.:
C25H20Cl2N2O3
Mol. Mass.:
467.344
SMILES:
OC(=O)CCCOc1ccccc1-c1cc(-c2ccccc2)n(n1)-c1ccc(Cl)c(Cl)c1
Structure:
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