Reaction Details Report a problem with these data
Target
Fatty acid-binding protein, adipocyte
Ligand
BDBM451168
Substrate
n/a
Meas. Tech.
Fluorescent Displacement Assay
IC50
>10000±n/a nM
Citation
 Fukunaga, K; Miyachi, H; Ishida, H; Ban, S Agent for treating synucleinopathy US Patent  US10709688 Publication Date 7/14/2020 
Target
Name:
Fatty acid-binding protein, adipocyte
Synonyms:
A-FABP | AFABP | ALBP | Adipocyte lipid-binding protein | FABP4 | FABP4_HUMAN | Fatty acid binding protein adipocyte | Fatty acid-binding protein 4 | Fatty acid-binding protein 4 (FABP4)
Type:
Enzyme
Mol. Mass.:
14719.23
Organism:
Homo sapiens (Human)
Description:
P15090
Residue:
132
Sequence:
MCDAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPNMIISVNGDVITIKSESTFKNTEISFILGQEFDEVTADDRKVKSTITLDGGVLVHVQKWDGKSTTIKRKREDDKLVVECVMKGVTSTRVYERA
  
Inhibitor
Name:
BDBM451168
Synonyms:
US10709688, Example 8
Type:
Small organic molecule
Emp. Form.:
C29H30N2O3
Mol. Mass.:
454.5601
SMILES:
CC(C)(C)c1ccc(cc1)-n1nc(cc1-c1ccccc1)-c1ccccc1OCCCC(O)=O
Structure:
Search PDB for entries with ligand similarity: