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Target
Retinol-binding protein 4
Ligand
BDBM50104159
Substrate
n/a
Meas. Tech.
In Vitro Assay
IC50
3.90±n/a nM
Citation
 Petrukhin, K; Cioffi, C; Johnson, G; Dobri, N; Freeman, E; Chen, P; Conlon, M; Zhu, L Octahydropyrrolopyrroles their preparation and use US Patent  US10787453 Publication Date 9/29/2020 
Target
Name:
Retinol-binding protein 4
Synonyms:
PRBP | Plasma retinol-binding protein | RBP | RBP4 | RET4_HUMAN | Retinol-binding protein 4 | Retinol-binding protein 4 (RBP4) | spa binding assay for rbp4
Type:
Protein
Mol. Mass.:
23008.75
Organism:
Homo sapiens (Human)
Description:
P02753
Residue:
201
Sequence:
MKWVWALLLLAALGSGRAERDCRVSSFRVKENFDKARFSGTWYAMAKKDPEGLFLQDNIVAEFSVDETGQMSATAKGRVRLLNNWDVCADMVGTFTDTEDPAKFKMKYWGVASFLQKGNDDHWIVDTDYDTYAVQYSCRLLNLDGTCADSYSFVFSRDPNGLPPEAQKIVRQRQEELCLARQYRLIVHNGYCDGRSERNLL
  
Inhibitor
Name:
BDBM50104159
Synonyms:
CHEMBL3594229 | US10787453, Compound 66
Type:
Small organic molecule
Emp. Form.:
C20H21F3N4O2
Mol. Mass.:
406.4015
SMILES:
[H][C@@]12CN(C[C@]1([H])CN(C2)c1ccccc1C(F)(F)F)c1nc(C)cc(n1)C(=O)OC |r|
Structure:
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