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Target
D(2) dopamine receptor
Ligand
BDBM301972
Substrate
n/a
Meas. Tech.
Binding Affinity Human Dopamine D2S Receptor Test
Ki
190±n/a nM
Citation
 Zhang, Y; Jin, C; Zhou, R Substituted heteroaryl compounds and methods of use thereof US Patent  US9598401 Publication Date 3/21/2017 
Target
Name:
D(2) dopamine receptor
Synonyms:
D2(Short) | Dopamine D2 S receptor
Type:
n/a
Mol. Mass.:
47370.77
Organism:
Homo sapiens (Human)
Description:
P14416-2
Residue:
414
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM301972
Synonyms:
3-(3-(4-(4-Cyanopyrimidin-2-yl)piperazin-1-yl)propyl)-1H-indole-5-carbonitrile | US9598401, Example 26
Type:
Small organic molecule
Emp. Form.:
C21H21N7
Mol. Mass.:
371.4383
SMILES:
N#Cc1ccc2[nH]cc(CCCN3CCN(CC3)c3nccc(n3)C#N)c2c1
Structure:
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