| Assay Method Information | |
| | ChEMBL_2266504 |
| Description: | Allosteric inhibition of IRS1 peptide-activated human recombinant SHP2 (Met1 to Leu525) expressed in Escherichia coli assessed as inhibition of dephosphorylation of 6,8-difluoro-4-methylumbelliferyl phosphate using DiFMUP as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured after 30 mins by DiFMUP assay |
| Affinity data for this assay | |
|---|---|
| If you find an error in this entry please send us an E-mail | |