Assay Method Information | |
| ethoxyresorufin-O-deethylase (EROD) assay |
Description: | This assay measures the induction of cytochrome P450-1A1 (CYP1A1), which is a major outcome of AhR activation. Whyte, J. J.; Jung, R. E.; Schmitt, C. J.; Tillitt, D. E. Crit. Rev. Toxicol. 2000, 30, 347. CYP1A1 selectively converts 7-ethoxyresorufin to the fluorescent product resorufin.Malassezin served as the positive control. |
Affinity data for this assay | |
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