Affinity DataKi: 19.6nM ΔG°: -43.6kJ/mole IC50: 52nMpH: 7.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at ...More data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Compound was tested for its ability to inhibit acetylcholinesterase (AChE) in rat brain; 0.024-0.040 uMMore data for this Ligand-Target Pair
Affinity DataKi: 47.1nM ΔG°: -41.4kJ/mole IC50: 114nMpH: 7.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at ...More data for this Ligand-Target Pair
Affinity DataKi: 279nMAssay Description:Inhibition of AChE in rat cortex using acetylthiocholine iodide as substrate by double Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+3nMAssay Description:Compound was tested for its ability to inhibit acetylcholinesterase (AChE) in rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 2.75E+3nMAssay Description:Inhibition of Sprague-Dawley rat brain AChE by Michaelis-Menten equationMore data for this Ligand-Target Pair
Affinity DataKi: 4.58E+3nMAssay Description:Inhibition of Sprague-Dawley rat brain AChE using acetylthiocholin iodide as substrate by Michaelis-Menten equationMore data for this Ligand-Target Pair
Affinity DataKi: 1.23E+4nMAssay Description:Compound was tested for its ability to inhibit acetylcholinesterase (AChE) in rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 3.10E+4nMpH: 7.0Assay Description:Inhibitory constant of the compound against rat brain acetylcholinesterase at pH 7.0More data for this Ligand-Target Pair
Affinity DataKi: >5.00E+5nMAssay Description:Compound was tested for its ability to inhibit acetylcholinesterase (AChE) in rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of rat cortex AchE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0700nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of rat cortex AchE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of rat cortex AchE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.380nMAssay Description:Inhibition concentration against rat acetylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of rat brain Acetylcholinesterase using acetylthiocholine as substrate in presence of BChE inhibitor ethopropazineMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of rat brain Acetylcholinesterase using acetylthiocholine as substrate in presence of BChE inhibitor ethopropazine by spectrophotometric m...More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of AChE in rat brain cortex using acetylthiocholine iodide as substrate incubated for 8 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibitory concentration against Acetylcholinesterase in rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate measured after 8 mins in presence of BuChE inhibitor ethopropazine by Ellma...More data for this Ligand-Target Pair
Affinity DataIC50: 0.520nMAssay Description:Inhibition of AChE in Wistar rat brain homogenates using acetylthiocholine iodide and DTNB as substrate after 10 mins by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
Affinity DataIC50: 0.660nMAssay Description:Inhibition of rat brain Acetylcholinesterase using acetylthiocholine as substrate in presence of BChE inhibitor ethopropazine by spectrophotometric m...More data for this Ligand-Target Pair
Affinity DataIC50: 0.680nMAssay Description:Inhibitory concentration of the compound was determined in vitro and ex vivo for anti-AChE activity in rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
Affinity DataIC50: 0.770nMAssay Description:Inhibition of rat brain Acetylcholinesterase using acetylthiocholine as substrate in presence of BChE inhibitor ethopropazine by spectrophotometric m...More data for this Ligand-Target Pair
Affinity DataIC50: 0.770nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
Affinity DataIC50: 0.780nMAssay Description:Inhibition of AchE in rat cortex by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.860nMAssay Description:Inhibition of rat cortex homogenate acetylcholinesterase using acetylthiocholine iodide as substrate incubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
Affinity DataIC50: 0.960nMAssay Description:Inhibition of rat cortex homogenate acetylcholinesterase using acetylthiocholine iodide as substrate incubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of rat brain AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.03nMAssay Description:Inhibition of AChE in Wistar rat brain homogenates using acetylthiocholine iodide and DTNB as substrate after 10 mins by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.16nMAssay Description:Inhibition of AChE in Wistar rat brain homogenates using acetylthiocholine iodide and DTNB as substrate after 10 mins by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
Affinity DataIC50: 1.33nMAssay Description:Inhibition of AChE in Wistar rat brain homogenates using acetylthiocholine iodide and DTNB as substrate after 10 mins by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of rat brain AChEMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition against acetylcholinesterase (AChE)More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibitory potency against acetylcholinesterase (AChE) of rat cortex homogenate with ethopropazine as BChE inhibitorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of rat AChEMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of rat AChEMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of rat AChEMore data for this Ligand-Target Pair
