Affinity DataKi: 0.0200nM ΔG°: -61.1kJ/moleT: 2°CAssay Description:To determine the effectiveness of representative compounds of this invention as histamine-3 receptor ligands (H3 receptor ligands), the following tes...More data for this Ligand-Target Pair
Affinity DataKi: 0.0200nMAssay Description:Binding affinity to histamine H3 receptor in rat cortical membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.0300nMAssay Description:Binding affinity to histamine H3 receptor in rat cortical membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.0320nM ΔG°: -59.9kJ/moleT: 2°CAssay Description:To determine the effectiveness of representative compounds of this invention as histamine-3 receptor ligands (H3 receptor ligands), the following tes...More data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:Binding affinity to histamine H3 receptor in rat cortical membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.0500nM ΔG°: -58.8kJ/moleT: 2°CAssay Description:To determine the effectiveness of representative compounds of this invention as histamine-3 receptor ligands (H3 receptor ligands), the following tes...More data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 0.0700nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.0700nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from rat cloned histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:In vitro binding affinity was determined as displacement of [3H]N-R-methylhistamine from C6 cell membranes expressing rat histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 0.110nMAssay Description:In vitro binding affinity for rat histamine H3 receptor using [3H]-N-alpha-methylhistamineMore data for this Ligand-Target Pair
Affinity DataKi: 0.110nMAssay Description:Inhibition of [125I]-iodoproxyfan from rat histamine H3 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.120nMAssay Description:Binding affinity at histamine H3 receptor in rat cortical membranes by [3H]-Nalpha-methylhistamine displacement.More data for this Ligand-Target Pair
Affinity DataKi: 0.120nMAssay Description:In vitro inhibitory activity against Histamine H3 receptor for K+ evoked depolarization-induced release of [3H]-histamine from synaptosomes of rat ce...More data for this Ligand-Target Pair
Affinity DataKi: 0.126nMAssay Description:Binding affinity of compound against Histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.126nMAssay Description:Affinity for histamine H3 receptor in rat cerebral cortex.More data for this Ligand-Target Pair
Affinity DataKi: 0.126nMAssay Description:Affinity for histamine H3 receptor in rat cerebral cortex.More data for this Ligand-Target Pair
Affinity DataKi: 0.148nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from rat histamine H3 receptor expressed in HEK293 cells after 45 mins by liquid scintillation spectromet...More data for this Ligand-Target Pair
Affinity DataKi: 0.158nMAssay Description:Binding affinity against H3 receptor in rat cerebral cortex membranes was evaluated using [3H]N-methyl-histamine as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:Displacement of N-[3H]-methylhistamine from histamine H3 receptor in rat cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.180nMAssay Description:Histamine H3 receptor affinity of compound was determined in rat cortical membranes using the H3 selective agonist ligand, [3H]N-alpha-methylhistamin...More data for this Ligand-Target Pair
Affinity DataKi: 0.180nMAssay Description:Binding affinity to rat cortical histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.180nMAssay Description:Inhibition of [3H]- N-alpha-methylhistamine from histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.180nMAssay Description:Ability to displace [3H]Nalpha-methylhistamine from histamine H3 receptors in homogenates of rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 0.182nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.195nMAssay Description:Binding affinity towards rat cortical H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]-R-alpha-ethylhistamine from histamine H3 receptor in rat cerebral cortical tissue membranes after 45 mins by liquid scintillatio...More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of N-[3H]-methylhistamine from histamine H3 receptor in rat cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H](R)-alpha-methylhistamine from rat recombinant histamine H3 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.25nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from rat cloned histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.More data for this Ligand-Target Pair
Affinity DataKi: 0.270nMAssay Description:In vitro binding affinity for rat histamine H3 receptor using [3H]-N-alpha-methylhistamineMore data for this Ligand-Target Pair
Affinity DataKi: 0.290nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 0.295nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H](R)-alpha-methylhistamine from rat recombinant histamine H3 receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortex membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Histamine H3 receptor antagonist activity in an assay with K+ evoked depolarization-induced release of [3H]-histamine from rat synaptosomes.More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Histamine H3 receptor affinity of compound was determined in rat cortical membranes using the H3 selective agonist ligand, [3H]N-alpha-methylhistamin...More data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from rat cloned histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.310nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from rat cloned histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.316nMAssay Description:Binding affinity towards rat histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.320nMAssay Description:Binding affinity to histamine H3 receptor in rat cortical membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.324nM ΔG°: -54.2kJ/moleT: 2°CAssay Description:To determine the effectiveness of representative compounds of this invention as histamine-3 receptor ligands (H3 receptor ligands), the following tes...More data for this Ligand-Target Pair
Affinity DataKi: 0.330nMAssay Description:Binding affinity at histamine H3 receptor in rat cortical membranes by [3H]-Nalpha-methylhistamine displacement.More data for this Ligand-Target Pair
