BindingDB Data by Journal




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Evidence of ternary complex formation in Trypanosoma cruzi trans-sialidase catalysis.BDB
J Biol Chem 289: 423-36 (2014)
Universidade Federal do Rio de Janeiro
Defining the communication between agonist and coactivator binding in the retinoid X receptor a ligand binding domain.BDB
J Biol Chem 289: 814-26 (2014)
University of Alabama at Birmingham
Identification of a small peptide that inhibits PCSK9 protein binding to the low density lipoprotein receptor.BDB
J Biol Chem 289: 942-55 (2014)
Genentech Inc
A L-lysine transporter of high stereoselectivity of the amino acid-polyamine-organocation (APC) superfamily: production, functional characterization, and structure modeling.BDB
J Biol Chem 289: 1377-87 (2014)
Max Planck Institute of Biophysics
The molecular chaperone Hsp70 activates protein phosphatase 5 (PP5) by binding the tetratricopeptide repeat (TPR) domain.BDB
J Biol Chem 289: 2908-17 (2014)
University of Michigan
Structure-guided development of specific pyruvate dehydrogenase kinase inhibitors targeting the ATP-binding pocket.BDB
J Biol Chem 289: 4432-43 (2014)
University of Texas Southwestern Medical Center
A novel sirtuin 2 (SIRT2) inhibitor with p53-dependent pro-apoptotic activity in non-small cell lung cancer.BDB
J Biol Chem 289: 5208-16 (2014)
Universitńt Duisburg-Essen
The different inhibition mechanisms of OXA-1 and OXA-24 ▀-lactamases are determined by the stability of active site carboxylated lysine.BDB
J Biol Chem 289: 6152-64 (2014)
Case Western Reserve University
Coregulator control of androgen receptor action by a novel nuclear receptor-binding motif.BDB
J Biol Chem 289: 8839-51 (2014)
Karlsruhe Institute of Technology
Affinity map of bromodomain protein 4 (BRD4) interactions with the histone H4 tail and the small molecule inhibitor JQ1.BDB
J Biol Chem 289: 9304-19 (2014)
Bayer HealthCare
Trimethylation of histone H3 lysine 36 by human methyltransferase PRDM9 protein.BDB
J Biol Chem 289: 12177-88 (2014)
University of Toronto
A novel small-molecule tumor necrosis factor a inhibitor attenuates inflammation in a hepatitis mouse model.BDB
J Biol Chem 289: 12457-66 (2014)
Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Fatty acid-binding protein 5 (FABP5) regulates cognitive function both by decreasing anandamide levels and by activating the nuclear receptor peroxisome proliferator-activated receptor ▀/d (PPAR▀/d) in the brain.BDB
J Biol Chem 289: 12748-58 (2014)
Case Western Reserve University School of Medicine
The Parkinson disease-linked LRRK2 protein mutation I2020T stabilizes an active state conformation leading to increased kinase activity.BDB
J Biol Chem 289: 13042-53 (2014)
Harvard NeuroDiscovery Center
Deciphering the binding of caveolin-1 to client protein endothelial nitric-oxide synthase (eNOS): scaffolding subdomain identification, interaction modeling, and biological significance.BDB
J Biol Chem 289: 13273-83 (2014)
St. Paul's Hospital's Centre of Heart and Lung Innovation
Biochemical, cellular, and biophysical characterization of a potent inhibitor of mutant isocitrate dehydrogenase IDH1.BDB
J Biol Chem 289: 13717-25 (2014)
National Institutes of Health
Structural basis of pharmacological chaperoning for human ▀-galactosidase.BDB
J Biol Chem 289: 14560-8 (2014)
The University of Tokyo
Structural basis for ligand regulation of the fatty acid-binding protein 5, peroxisome proliferator-activated receptor ▀/d (FABP5-PPAR▀/d) signaling pathway.BDB
J Biol Chem 289: 14941-54 (2014)
Emory University
Functional rescue of Kallmann syndrome-associated prokineticin receptor 2 (PKR2) mutants deficient in trafficking.BDB
J Biol Chem 289: 15518-26 (2014)
Central South University
Structural basis for the recognition of peptide RJPXD33 by acyltransferases in lipid A biosynthesis.BDB
J Biol Chem 289: 15527-35 (2014)
University of Michigan
Oxysterol-binding protein (OSBP)-related protein 4 (ORP4) is essential for cell proliferation and survival.BDB
J Biol Chem 289: 15705-17 (2014)
Dalhousie University
Rational design of broad spectrum antibacterial activity based on a clinically relevant enoyl-acyl carrier protein (ACP) reductase inhibitor.BDB
J Biol Chem 289: 15987-6005 (2014)
University of Wuerzburg
Inhibition of the ribonuclease H activity of HIV-1 reverse transcriptase by GSK5750 correlates with slow enzyme-inhibitor dissociation.BDB
J Biol Chem 289: 16270-7 (2014)
McGill University
Allosteric inhibitors of the Eya2 phosphatase are selective and inhibit Eya2-mediated cell migration.BDB
J Biol Chem 289: 16349-61 (2014)
University of Colorado School of Medicine
In vitro resistance selections for Plasmodium falciparum dihydroorotate dehydrogenase inhibitors give mutants with multiple point mutations in the drug-binding site and altered growth.BDB
J Biol Chem 289: 17980-95 (2014)
Harvard School of Public Health
Human UTY(KDM6C) is a male-specific N┐-methyl lysyl demethylase.BDB
J Biol Chem 289: 18302-13 (2014)
University of Oxford
Opioid receptor function is regulated by post-endocytic peptide processing.BDB
J Biol Chem 289: 19613-26 (2014)
Icahn School of Medicine at Mount Sinai
Two amino acid residues confer different binding affinities of Abelson family kinase SRC homology 2 domains for phosphorylated cortactin.BDB
J Biol Chem 289: 19704-13 (2014)
Yale University
ORA1, a zebrafish olfactory receptor ancestral to all mammalian V1R genes, recognizes 4-hydroxyphenylacetic acid, a putative reproductive pheromone.BDB
J Biol Chem 289: 19778-88 (2014)
German Institute of Human Nutrition Potsdam-Rehbruecke
Structure of the Acinetobacter baumannii dithiol oxidase DsbA bound to elongation factor EF-Tu reveals a novel protein interaction site.BDB
J Biol Chem 289: 19869-80 (2014)
University of Queensland
Structure of REV-ERB▀ ligand-binding domain bound to a porphyrin antagonist.BDB
J Biol Chem 289: 20054-66 (2014)
The Scripps Research Institute
Digoxin derivatives with enhanced selectivity for the a2 isoform of Na,K-ATPase: effects on intraocular pressure in rabbits.BDB
J Biol Chem 289: 21153-62 (2014)
Weizmann Institute of Science
The role of a novel auxiliary pocket in bacterial phenylalanyl-tRNA synthetase druggability.BDB
J Biol Chem 289: 21651-62 (2014)
AstraZeneca R&D Boston
Chemical proteomics identifies heterogeneous nuclear ribonucleoprotein (hnRNP) A1 as the molecular target of quercetin in its anti-cancer effects in PC-3 cells.BDB
J Biol Chem 289: 22078-89 (2014)
National Taiwan University