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Compounds Sorted by Binding Data per Compound

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22   23   24   25   26   27   28   29   30   31   32   33   34   35   36   37   38   39   40   41   42   
43   44   45   46   47   48   49   50   51   52   53   54   55   56   57   58   59   60   61   62   63   
64   65   66   67   68   69   70   71   72   73   74   75   76   77   78   79   80   81   82   83   84   
85   86   87   88   89   90   91   92   93   94   95   96   97   98   99   100   101   102   103   104   105   
106   108   109   110   111   112   113   114   115   116   117   118   119   120   121   123   124   125   126   127   128   
129   130   131   132   133   134   135   137   138   139   140   142   143   144   146   148   150   152   153   154   155   
157   158   159   160   161   162   163   164   166   168   171   173   174   177   178   182   183   185   186   188   189   
190   191   194   198   199   202   203   204   207   209   213   217   221   223   224   232   233   237   238   239   241   
249   251   253   262   271   273   277   282   285   286   292   295   303   305   307   308   320   325   330   333   335   
336   337   338   344   349   360   370   378   389   397   413   425   430   435   442   443   444   445   446   447   448   
450   453   456   457   458   460   461   463   465   466   467   468   471   472   475   479   480   482   498   512   513   
521   530   535   541   558   593   622   637   644   793   804   821   825   831   834   841   848   851   852   854   856   
868   883   887   892   913   923   924   938   939   994   999   1011   1013   1027   1031   1047   1070   1072   1099   1125   1196   
1484   1506   1618   1796   
Compounds Sorted Alphabetically
Compound Name
(alphabetical)
Enz. Inhib. DataITC DataBinding TargetsAlternate Compound Names
KiIC50KdEC50KoffKonOther
BDBM101536
PNG
56010000
  • PAK 1/CDC42
  • Serine/threonine-protein kinase PAK 4
  • CHEMBL3128043
  • US8530494, 203
  • US8530652, 114
  • US8530652, 63
BDBM10330
PNG
111000000
  • Caspase-1
  • Caspase-3
  • Caspase-6
  • Caspase-7
  • Caspase-8
  • (S)-1-(4-Methoxybenzyl)-5-(2-phenoxymethyl-pyrrolidine-1-sulfonyl)-1H-indole-2,3-dione
  • 1-[(4-methoxyphenyl)methyl]-5-{[(2S)-2-(phenoxymethyl)pyrrolidine-1-]sulfonyl}-2,3-dihydro-1H-indole-2,3-dione
  • CHEMBL200677
  • Pyrrolidine Isatin Analogue 11b
BDBM10334
PNG
111000000
  • Caspase-1
  • Caspase-3
  • Caspase-6
  • Caspase-7
  • Caspase-8
  • (S)-1-(4-Hydroxybenzyl)-5-(2-phenoxymethyl-pyrrolidine-1-sulfonyl)-1H-indole-2,3-dione
  • 1-[(4-hydroxyphenyl)methyl]-5-{[(2S)-2-(phenoxymethyl)pyrrolidine-1-]sulfonyl}-2,3-dihydro-1H-indole-2,3-dione
  • CHEMBL200927
  • Pyrrolidine Isatin Analogue 11f
BDBM10355
PNG
48000000
  • Caspase-1
  • Caspase-3
  • hIL-1beta
  • (3S)-3-[(2S)-2-[(2S)-2-[(2S)-2-acetamido-3-(4-hydroxyphenyl)propanamido]-3-methylbutanamido]propanamido]-4-oxobutanoic acid
  • Ac-YVAD-CHO
  • CHEMBL37630
BDBM103796
PNG
90030000
  • Beta-2 adrenergic receptor
  • Muscarinic acetylcholine receptor M3
  • US8551978, 322
  • US8551978, 323
  • US8816088, I-66
  • US8816088, I-67
  • US9394275, I-66
  • US9572802, Compound I-67
  • US9682957, I-67
BDBM104213
PNG
012000000
  • Serine/threonine-protein kinase PIM-3
  • Serine/threonine-protein kinase pim-1
  • Serine/threonine-protein kinase pim-2
  • US8575145, 120
  • US8575145, 121
  • US8575145, 150
  • US8575145, 151
  • US8575145, 90
  • US8575145, 91
BDBM10458
PNG
46110000
  • Acetylcholinesterase
  • Carboxylic ester hydrolase
  • Choline transporter
  • Plasminogen
  • Potassium voltage-gated channel subfamily H member 2
  • Pteridine reductase 1
  • Thrombin and coagulation factor X
  • Trypsin
  • Twik-RElated Potassium (K+) channel 1 (TREK1)
  • Voltage-gated potassium channel
  • Voltage-gated potassium channel subfamily A member 1/beta-1
  • 4-AP
  • 4-Aminopyridine 10
  • CHEMBL284348
  • DALFAMPRIDINE
  • pyridin-4-amine
BDBM106722
PNG
012000000
  • Nitric oxide synthase, brain
  • Nitric oxide synthase, endothelial
  • Nitric oxide synthase, inducible
  • Sodium-dependent noradrenaline transporter
  • CHEMBL2036264
  • US8586620, 114
BDBM106896
PNG
93000000
  • Serine/threonine-protein kinase pim-1
  • Serine/threonine-protein kinase pim-2
  • Serine/threonine-protein kinase pim-3
  • US8592455, 96
BDBM107486
PNG
012000000
  • 11-beta-hydroxysteroid dehydrogenase 1
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 3A
  • US8575157, 200
  • US8592410, Comparator 12
  • US8598163, 70
BDBM10844
PNG
012000000
  • Axin-1/Glycogen synthase kinase-3 beta
  • Cyclin-Dependent Kinase 1 (CDK1)
  • Cyclin-Dependent Kinase 5 (CDK5)
  • Dual specificty protein kinase CLK1
  • Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
  • Dual-specificity tyrosine-phosphorylation regulated kinase 1A
  • Glycogen Synthase Kinase-3, beta
  • Mitogen-activated protein kinase kinase kinase 14
  • cAMP-Dependent Protein Kinase (PKA)
  • cGMP-Dependent Protein Kinase
  • 4-(1H-indol-3-yl)pyrimidin-2-amine
  • Meridianin G
BDBM10854
PNG
13800000
  • Chitinase 1
  • Chitinase B
  • Chitinase Mutant (A217G)
  • Chitinase Mutant (D175A)
  • Chitinase Mutant (E322A)
  • Chitinase Mutant (M243A)
  • Chitinase Mutant (R301K)
  • Chitinase Mutant (T138A)
  • Chitinase Mutant (Y245F)
  • Endochitinase B1
  • 4-[(1S,4R,10S,13S,16S,18R)-10-{3-[(acetamidomethanimidoyl)amino]propyl}-18-hydroxy-16-(1H-imidazol-4-ylmethyl)-3,9,12,15,20-pentaoxo-2,8,11,14,17-pentaazatricyclo[15.2.1.0^{4,8}]icosan-13-yl]butanoic acid
  • Argadin
  • CHEMBL445236
BDBM108945
PNG
012000000
  • Activin receptor type-1
  • Activin receptor type-1B
  • Activin receptor type-1B/Activin receptor-like kinase 4 (ALK-4)
  • Activin receptor-like kinase 3 (ALK-3)
  • Bone morphogenetic protein receptor type-1B (BMPR1B)
  • Serine/threonine-protein kinase receptor R3
  • Serine/threonine-protein kinase receptor R3 (ALK1)
  • TGF-beta receptor type-1
  • US10017516, Compound 48
  • US9682983, 48
BDBM11140
PNG
012000000
  • Dipeptidyl peptidase 2 (DPP II)
  • Dipeptidyl peptidase 4
  • Dipeptidyl peptidase 9
  • Dipeptidyl peptidase VIII
  • (1S,2S)-1-(dimethylcarbamoyl)-1-[4-(4-fluorophenyl)phenyl]-3-[(3S)-3-fluoropyrrolidin-1-yl]-3-oxopropan-2-aminium; 2,2,2-trifluoroacetate
  • beta-dimethylamide 4
  • beta-substituted phenylalanine deriv. 22
  • phenylalanine derived inhibitor, 3
BDBM11189
PNG
012000000
  • Dipeptidyl peptidase 2 (DPP II)
  • Dipeptidyl peptidase 4
  • Dipeptidyl peptidase 9
  • Dipeptidyl peptidase VIII
  • (2S,3S)-3-[4-(4-fluorophenyl)phenyl]-1-[(3S)-3-fluoropyrrolidin-1-yl]-1-oxobutan-2-aminium; 2,2,2-trifluoroacetate
  • 3-(S)-fluoropyrrolidide 25
  • beta-substituted phenylalanine deriv. 14
  • phenylalanine derived inhibitor, 4
BDBM11343
PNG
102000000
  • 72 kDa type IV collagenase
  • Carbonic Anhydrase IV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 2
  • Collagenase (ChC)
  • Interstitial collagenase
  • Matrix Metalloproteinase-8 (MMP-8)
  • Matrix metalloproteinase 12
  • Matrix metalloproteinase-9
  • (2S)-2-[benzyl(4-methoxybenzene)sulfonamido]-N-hydroxy-3-methylbutanamide
  • Hydroxamate 24
  • N-4-Methoxyphenylsulfonyl-N-benzyl-L-valine hydroxamate
BDBM11362
PNG
111000000
  • 72 kDa type IV collagenase
  • Carbonic Anhydrase IV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 2
  • Collagenase (ChC)
  • Interstitial collagenase
  • Matrix Metalloproteinase-8 (MMP-8)
  • Matrix metalloproteinase-9
  • 2-{[(2-chlorophenyl)methyl](1,1,2,2,3,3,4,4,4-nonafluorobutane)sulfonamido}-N-hydroxypropanamide
  • Hydroxamate 43
  • hydroxamate deriv. B4
BDBM11363
PNG
111000000
  • 72 kDa type IV collagenase
  • Carbonic Anhydrase IV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 2
  • Collagenase (ChC)
  • Interstitial collagenase
  • Matrix Metalloproteinase-8 (MMP-8)
  • Matrix metalloproteinase-9
  • 2-{[(2-chlorophenyl)methyl](2,3,4,5,6-pentafluorobenzene)sulfonamido}-N-hydroxypropanamide
  • Hydroxamate 44
  • hydroxamate deriv. B21
BDBM11364
PNG
111000000
  • 72 kDa type IV collagenase
  • Carbonic Anhydrase IV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 2
  • Collagenase (ChC)
  • Interstitial collagenase
  • Matrix Metalloproteinase-8 (MMP-8)
  • Matrix metalloproteinase-9
  • 2-{[(2-chlorophenyl)methyl](4-methoxybenzene)sulfonamido}-N-hydroxypropanamide
  • Hydroxamate 45
  • hydroxamate deriv. B24
BDBM11719
PNG
012000000
  • Dipeptidyl peptidase 2 (DPP II)
  • Dipeptidyl peptidase 4
  • Dipeptidyl peptidase 9
  • Dipeptidyl peptidase VIII
  • Fibroblast Activation Protein (FAP)
  • Fibroblast activation protein alpha
  • (2S)-1-(2-{[4-(2,3-dihydro-1H-isoindol-2-yl)-2-methyl-4-oxobutan-2-yl]amino}acetyl)pyrrolidine-2-carbonitrile
  • (2S)-Cyanopyrrolidine analogue 21d
  • (2S)-cyanopyrrolidine 4
  • 2-[3-[2-[2-Cyano-(S)-pyrrolidin-1-yl]-2-oxoethylamino]-3-methyl-1-oxobutyl]-1,3-dihydroisoindole
BDBM118134
PNG
012000000
  • Activin receptor type-1
  • Activin receptor type-1B
  • Activin receptor type-1B/Activin receptor-like kinase 4 (ALK-4)
  • Activin receptor-like kinase 3 (ALK-3)
  • Bone morphogenetic protein receptor type-1B (BMPR1B)
  • Serine/threonine-protein kinase receptor R3
  • Serine/threonine-protein kinase receptor R3 (ALK1)
  • TGF-beta receptor type-1
  • US10017516, Compound 3
  • US9682983, 3
BDBM118138
PNG
012000000
  • Activin receptor type-1
  • Activin receptor type-1B
  • Activin receptor type-1B/Activin receptor-like kinase 4 (ALK-4)
  • Activin receptor-like kinase 3 (ALK-3)
  • Bone morphogenetic protein receptor type-1B (BMPR1B)
  • Serine/threonine-protein kinase receptor R3
  • Serine/threonine-protein kinase receptor R3 (ALK1)
  • TGF-beta receptor type-1
  • US10017516, Compound 4
  • US9682983, 4
BDBM118234
PNG
012000000
  • Phosphatidylinositol 3-kinase regulatory subunit beta/Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform/gamma isoform
  • US8653092, 1
BDBM11870
PNG
57000000
  • 72 kDa type IV collagenase
  • Collagenase 3
  • Interstitial collagenase
  • Matrix Metalloproteinase-8 (MMP-8)
  • Matrix metalloproteinase-14 (MMP14)
  • Matrix metalloproteinase-9
  • Stromelysin-1
  • 4-{[4-(4-Chlorophenoxy)phenyl]sulfonyl}-N-hydroxy tetrahydro-2H-pyran-4-carboxamide
  • 4-{[4-(4-chlorophenoxy)benzene]sulfonyl}-N-hydroxyoxane-4-carboxamide
  • alpha-sulfone 21
BDBM119440
PNG
111000000
  • Cereblon/Histone deacetylase 6
  • Histone deacetylase 1
  • Histone deacetylase 10
  • Histone deacetylase 11
  • Histone deacetylase 2
  • Histone deacetylase 3
  • Histone deacetylase 4
  • Histone deacetylase 5
  • Histone deacetylase 7
  • Histone deacetylase 8
  • Histone deacetylase 9
  • Prostaglandin E2 receptor EP2 subtype
  • BDBM119696
  • US8685986, 15
BDBM123325
PNG
44400000
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Orexin receptor type 1
  • Orexin receptor type 2
  • Potassium voltage-gated channel subfamily H member 2
  • US8742106, 1.4
BDBM12355
PNG
39000000
  • Cytochrome P450 2A6
  • Cytochrome P450 2B6
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 2E1
  • Cytochrome P450 3A
  • 3-(thiophen-3-yl)pyridine
  • CHEMBL361153
  • US8609708,11
  • nicotine 3-heteroaromatic analogue 8
BDBM127726
PNG
012000000
  • High affinity nerve growth factor receptor
  • JAK2 (aa 808-1132)
  • Tyrosine-protein kinase JAK2
  • US10251889, Example 100
  • US8791123, 99
  • US9782415, Example 99
  • US9796724, Example 100
BDBM127808
PNG
012000000
  • High affinity nerve growth factor receptor
  • Non-receptor tyrosine-protein kinase TYK2
  • Tyk2
  • Tyrosine-protein kinase JAK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase JAK3
  • US8791123, 181
  • US9782415, Example 181
BDBM127883
PNG
012000000
  • Activin receptor type-1
  • Activin receptor type-1B
  • Activin receptor type-1B/Activin receptor-like kinase 4 (ALK-4)
  • Activin receptor-like kinase 3 (ALK-3)
  • Bone morphogenetic protein receptor type-1B (BMPR1B)
  • Serine/threonine-protein kinase receptor R3
  • Serine/threonine-protein kinase receptor R3 (ALK1)
  • TGF-beta receptor type-1
  • US10017516, Compound 6
  • US9682983, 6
BDBM135812
PNG
012000000
  • 3',5'-cyclic phosphodiesterase
  • Lipopolysaccharide-induced tumor necrosis factor-alpha factor
  • Tumor necrosis factor
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4B
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4B (PDE4B2)
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4D
  • phosphodiesterase 4B2
  • phosphodiesterase 4D
  • US10085990, Example 30
  • US10568888, Example 30
  • US8853226, 30
  • US9393245, 30
  • US9833457, 30
BDBM135813
PNG
012000000
  • 3',5'-cyclic phosphodiesterase
  • Lipopolysaccharide-induced tumor necrosis factor-alpha factor
  • Tumor necrosis factor
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4B
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4B (PDE4B2)
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4D
  • phosphodiesterase 4B2
  • phosphodiesterase 4D
  • US10085990, Example 32
  • US10568888, Example 32
  • US8853226, 32
  • US9393245, 32
  • US9833457, 32
BDBM135814
PNG
012000000
  • 3',5'-cyclic phosphodiesterase
  • Lipopolysaccharide-induced tumor necrosis factor-alpha factor
  • Tumor necrosis factor
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4B
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4B (PDE4B2)
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4D
  • phosphodiesterase 4B2
  • phosphodiesterase 4D
  • US10085990, Example 33
  • US10568888, Example 33
  • US8853226, 33
  • US9393245, 33
  • US9833457, 33
BDBM135815
PNG
012000000
  • 3',5'-cyclic phosphodiesterase
  • Lipopolysaccharide-induced tumor necrosis factor-alpha factor
  • Tumor necrosis factor
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4B
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4B (PDE4B2)
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4D
  • phosphodiesterase 4B2
  • phosphodiesterase 4D
  • US10085990, Example 51
  • US10568888, Example 51
  • US8853226, 51
  • US9393245, 51
  • US9833457, 51
BDBM135816
PNG
012000000
  • 3',5'-cyclic phosphodiesterase
  • Lipopolysaccharide-induced tumor necrosis factor-alpha factor
  • Tumor necrosis factor
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4B
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4B (PDE4B2)
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4D
  • phosphodiesterase 4B2
  • phosphodiesterase 4D
  • US10085990, Example 54
  • US10568888, Example 54
  • US8853226, 54
  • US9393245, 54
  • US9833457, 54
BDBM135817
PNG
012000000
  • 3',5'-cyclic phosphodiesterase
  • Lipopolysaccharide-induced tumor necrosis factor-alpha factor
  • Tumor necrosis factor
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4B
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4B (PDE4B2)
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4D
  • phosphodiesterase 4B2
  • phosphodiesterase 4D
  • US10085990, Example 84
  • US10568888, Example 84
  • US8853226, 84
  • US9393245, 84
  • US9833457, 84
BDBM135818
PNG
012000000
  • 3',5'-cyclic phosphodiesterase
  • Lipopolysaccharide-induced tumor necrosis factor-alpha factor
  • Tumor necrosis factor
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4B
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4B (PDE4B2)
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4D
  • phosphodiesterase 4B2
  • phosphodiesterase 4D
  • US10085990, Example 92
  • US10568888, Example 92
  • US8853226, 92
  • US9393245, 92
  • US9833457, 92
BDBM135820
PNG
012000000
  • 3',5'-cyclic phosphodiesterase
  • Lipopolysaccharide-induced tumor necrosis factor-alpha factor
  • Tumor necrosis factor
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4B
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4B (PDE4B2)
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4D
  • phosphodiesterase 4B2
  • phosphodiesterase 4D
  • US10085990, Example 115
  • US10568888, Example 115
  • US8853226, 115
  • US9393245, 115
  • US9833457, 115
BDBM135821
PNG
012000000
  • 3',5'-cyclic phosphodiesterase
  • Lipopolysaccharide-induced tumor necrosis factor-alpha factor
  • Tumor necrosis factor
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4B
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4B (PDE4B2)
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4D
  • phosphodiesterase 4B2
  • phosphodiesterase 4D
  • US10085990, Example 118
  • US10568888, Example 118
  • US8853226, 118
  • US9393245, 118
  • US9833457, 118
BDBM135824
PNG
012000000
  • 3',5'-cyclic phosphodiesterase
  • Lipopolysaccharide-induced tumor necrosis factor-alpha factor
  • Tumor necrosis factor
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4B
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4B (PDE4B2)
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4D
  • phosphodiesterase 4B2
  • phosphodiesterase 4D
  • US10085990, Example 127
  • US10568888, Example 127
  • US8853226, 127
  • US9393245, 127
  • US9833457, 127
BDBM136570
PNG
012000000
  • Beta-secretase 1
  • Cathepsin D
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C8
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Potassium voltage-gated channel subfamily H member 2
  • US8865706, 9
BDBM13940
PNG
1200000
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