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60 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Discovery of a sulfamate-based steroid sulfatase inhibitor with intrinsic selective estrogen receptor modulator properties.EBI
Chu De Qu£Bec - Research Center (Chul, T4)
Recent developments of C-4 substituted coumarin derivatives as anticancer agents.EBI
Central University Of Punjab
Sulfatase inhibitors for recidivist breast cancer treatment: A chemical review.EBI
Punjabi University
Design, synthesis, and biological evaluation of new arylamide derivatives possessing sulfonate or sulfamate moieties as steroid sulfatase enzyme inhibitors.EBI
University Of Sharjah
Recent developments in steroidal and nonsteroidal aromatase inhibitors for the chemoprevention of estrogen-dependent breast cancer.EBI
American University Of Ras Al Khaimah
Discovery and Development of the Aryl O-Sulfamate Pharmacophore for Oncology and Women's Health.EBI
University Of Bath
Synthesis of bicoumarin thiophosphate derivatives as steroid sulfatase inhibitors.EBI
Gdansk University Of Technology
A-ring substituted 17ß-arylsulfonamides of 17ß-aminoestra-1,3,5(10)-trien-3-ol as highly potent reversible inhibitors of steroid sulfatase.EBI
University Of Waterloo
Design and synthesis of silicon-containing steroid sulfatase inhibitors possessing pro-estrogen antagonistic character.EBI
The University Of Tokyo
Synthesis, structure-activity relationship of iodinated-4-aryloxymethyl-coumarins as potential anti-cancer and anti-mycobacterial agents.EBI
P.C. Jabin Science College
Evaluation of sulfatase-directed quinone methide traps for proteomics.EBI
Bielefeld University
Synthesis and evaluation of analogues of estrone-3-O-sulfamate as potent steroid sulfatase inhibitors.EBI
University Of Bath
Highly potent first examples of dual aromatase-steroid sulfatase inhibitors based on a biphenyl template.EBI
University Of Bath
Structure-activity relationships of C-17 cyano-substituted estratrienes as anticancer agents.EBI
University Of Bath
2-(1-adamantyl)-4-(thio)chromenone-6-carboxylic acids: potent reversible inhibitors of human steroid sulfatase.EBI
Novartis Institute For Biomedical Research Vienna
Estrone formate: a novel type of irreversible inhibitor of human steroid sulfatase.EBI
Novartis Institutes For Biomedical Research Gdc
Estrogenic potential of 2-alkyl-4-(thio)chromenone 6-O-sulfamates: potent inhibitors of human steroid sulfatase.EBI
Novartis Research Institute Vienna
2-Substituted 4-(thio)chromenone 6-O-sulfamates: potent inhibitors of human steroid sulfatase.EBI
Novartis Research Institute Vienna
Structure-activity relationships of 17alpha-derivatives of estradiol as inhibitors of steroid sulfatase.EBI
Laval University
Synthesis and biological activity of the superestrogen (E)-17-oximino-3-O-sulfamoyl-1,3,5(10)-estratriene: x-ray crystal structure of (E)-17-oximino-3-hydroxy-1,3,5(10)-estratriene.EBI
University Of Bath
Potent inhibition of steroid sulfatase activity by 3-O-sulfamate 17alpha-benzyl(or 4'-tert-butylbenzyl)estra-1,3,5(10)-trienes: combination of two substituents at positions C3 and c17alpha of estradiol.EBI
Laval University
Active site directed inhibition of estrone sulfatase by nonsteroidal coumarin sulfamates.EBI
University Of Bath
Estrone sulfamates: potent inhibitors of estrone sulfatase with therapeutic potential.EBI
University Of Bath
Inhibition of estrone sulfatase (ES) by alkyl and cycloalkyl ester derivatives of 4-[(aminosulfonyl)oxy] benzoic acid.EBI
Kingston University
2-Alkylsulfanyl estrogen derivatives: synthesis of a novel class of multi-targeted anti-tumour agents.EBI
University Of Bath
The difluoromethylene group as a replacement for the labile oxygen in steroid sulfates: a new approach to steroid sulfatase inhibitors.EBI
University Of Waterloo
6-(2-adamantan-2-ylidene-hydroxybenzoxazole)-O-sulfamate: a potent non-steroidal irreversible inhibitor of human steroid sulfatase.EBI
Novartis Forschungsinstitut
The mechanism of the irreversible inhibition of estrone sulfatase (ES) through the consideration of a range of methane- and amino-sulfonate-based compounds.EBI
Kingston University
Inhibition of estrone sulfatase (ES) by derivatives of 4-[(aminosulfonyl)oxy] benzoic acid.EBI
Kingston University
4,4'-Benzophenone-O,O'-disulfamate: a potent inhibitor of steroid sulfatase.EBI
Novartis Research Institute Vienna
Design, synthesis and biochemical evaluation of AC ring mimics as novel inhibitors of the enzyme estrone sulfatase (ES).EBI
Kingston University
A novel type of nonsteroidal estrone sulfatase inhibitors.EBI
Hans-Kn�Ll Institute Of Natural Products Research
Acid dissociation constant, a potential physicochemical factor in the inhibition of the enzyme estrone sulfatase (ES).EBI
Kingston University
Novel inhibitors of the enzyme estrone sulfatase (ES).EBI
Kingston University
Determination and use of a transition state for the enzyme estrone sulfatase (ES) from a proposed reaction mechanism.EBI
Kingston University
Hydrophobicity, a physicochemical factor in the inhibition of the enzyme estrone sulfatase (ES).EBI
Kingston University
Derivation of a possible transition-state for the reaction catalysed by the enzyme estrone Sulfatase (ES).EBI
Kingston University
17 alpha-alkyl- or 17 alpha-substituted benzyl-17 beta-estradiols: a new family of estrone-sulfatase inhibitors.EBI
Laval University
 
Phosphonates and thiophosphonates as sulfate surrogates: synthesis of estrone 3-methylthiophosphonate, a potent inhibitor of estrone sulfataseEBI
TBA
17ß-Arylsulfonamides of 17ß-aminoestra-1,3,5(10)-trien-3-ol as highly potent inhibitors of steroid sulfatase.EBI
University Of Waterloo
Inhibition of steroid sulfatase with 4-substituted estrone and estradiol derivatives.EBI
University Of Waterloo
Hybrid Dual Aromatase-Steroid Sulfatase Inhibitors with Exquisite Picomolar Inhibitory ActivityEBI
TBA
3,17-disubstituted 2-alkylestra-1,3,5(10)-trien-3-ol derivatives: synthesis, in vitro and in vivo anticancer activity.EBI
University Of Bath
Thiosemicarbazones of formyl benzoic acids as novel potent inhibitors of estrone sulfatase.EBI
Institute For Natural Products Research And Infection Biology
2-substituted estradiol bis-sulfamates, multitargeted antitumor agents: synthesis, in vitro SAR, protein crystallography, and in vivo activity.EBI
University Of Bath
A-ring-substituted estrogen-3-O-sulfamates: potent multitargeted anticancer agents.EBI
University Of Bath
N-Acyl arylsulfonamides as novel, reversible inhibitors of human steroid sulfatase.EBI
Novartis Institutes For Biomedical Research
Nortropinyl-arylsulfonylureas as novel, reversible inhibitors of human steroid sulfatase.EBI
Novartis Research Institute Vienna
Design and synthesis of dansyl-labeled inhibitors of steroid sulfatase for optical imaging.EBI
Chu De Qu£Bec - Research Center
A new series of aryl sulfamate derivatives: Design, synthesis, and biological evaluation.EBI
University Of Sharjah
Synthesis and in vitro evaluation of piperazinyl-ureido sulfamates as steroid sulfatase inhibitors.EBI
University Of Cagliari
Sulfamates in drug design and discovery: Pre-clinical and clinical investigations.EBI
University Of Sharjah
Estrogen signaling: An emanating therapeutic target for breast cancer treatment.EBI
Indian Institute Of Technology (Bhu)
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design.EBI
Bristol-Myers Squibb
Synthesis and biological evaluation of fluorinated N-benzoyl and N-phenylacetoyl derivatives of 3-(4-aminophenyl)-coumarin-7-O-sulfamate as steroid sulfatase inhibitors.EBI
Gdansk University Of Technology
First Dual Inhibitors of Steroid Sulfatase (STS) and 17?-Hydroxysteroid Dehydrogenase Type 1 (17?-HSD1): Designed Multiple Ligands as Novel Potential Therapeutics for Estrogen-Dependent Diseases.EBI
Saarland University
URB602 inhibits monoacylglycerol lipase and selectively blocks 2-arachidonoylglycerol degradation in intact brain slices.BDB
University Of California Irvine
Inverse in silico screening for identification of kinase inhibitor targets.BDB
University Of Munich
Thermodynamics of the molecular and chiral recognition of cycloalkanols and camphor by modified beta-cyclodextrins possessing simple aromatic tethers.BDB
Nankai University
Indoleamine 2,3-dioxygenase is the anticancer target for a novel series of potent naphthoquinone-based inhibitors.BDB
Bryn Mawr College