60 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Article Title
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Discovery of a sulfamate-based steroid sulfatase inhibitor with intrinsic selective estrogen receptor modulator properties.
Chu De Qu£Bec - Research Center (Chul, T4)
Recent developments of C-4 substituted coumarin derivatives as anticancer agents.
Central University Of Punjab
Sulfatase inhibitors for recidivist breast cancer treatment: A chemical review.
Punjabi University
Design, synthesis, and biological evaluation of new arylamide derivatives possessing sulfonate or sulfamate moieties as steroid sulfatase enzyme inhibitors.
University Of Sharjah
Recent developments in steroidal and nonsteroidal aromatase inhibitors for the chemoprevention of estrogen-dependent breast cancer.
American University Of Ras Al Khaimah
Discovery and Development of the Aryl O-Sulfamate Pharmacophore for Oncology and Women's Health.
University Of Bath
Synthesis of bicoumarin thiophosphate derivatives as steroid sulfatase inhibitors.
Gdansk University Of Technology
A-ring substituted 17ß-arylsulfonamides of 17ß-aminoestra-1,3,5(10)-trien-3-ol as highly potent reversible inhibitors of steroid sulfatase.
University Of Waterloo
Design and synthesis of silicon-containing steroid sulfatase inhibitors possessing pro-estrogen antagonistic character.
The University Of Tokyo
Synthesis, structure-activity relationship of iodinated-4-aryloxymethyl-coumarins as potential anti-cancer and anti-mycobacterial agents.
P.C. Jabin Science College
Evaluation of sulfatase-directed quinone methide traps for proteomics.
Bielefeld University
Synthesis and evaluation of analogues of estrone-3-O-sulfamate as potent steroid sulfatase inhibitors.
University Of Bath
Highly potent first examples of dual aromatase-steroid sulfatase inhibitors based on a biphenyl template.
University Of Bath
Structure-activity relationships of C-17 cyano-substituted estratrienes as anticancer agents.
University Of Bath
2-(1-adamantyl)-4-(thio)chromenone-6-carboxylic acids: potent reversible inhibitors of human steroid sulfatase.
Novartis Institute For Biomedical Research Vienna
Estrone formate: a novel type of irreversible inhibitor of human steroid sulfatase.
Novartis Institutes For Biomedical Research Gdc
Estrogenic potential of 2-alkyl-4-(thio)chromenone 6-O-sulfamates: potent inhibitors of human steroid sulfatase.
Novartis Research Institute Vienna
2-Substituted 4-(thio)chromenone 6-O-sulfamates: potent inhibitors of human steroid sulfatase.
Novartis Research Institute Vienna
Structure-activity relationships of 17alpha-derivatives of estradiol as inhibitors of steroid sulfatase.
Laval University
Synthesis and biological activity of the superestrogen (E)-17-oximino-3-O-sulfamoyl-1,3,5(10)-estratriene: x-ray crystal structure of (E)-17-oximino-3-hydroxy-1,3,5(10)-estratriene.
University Of Bath
Potent inhibition of steroid sulfatase activity by 3-O-sulfamate 17alpha-benzyl(or 4'-tert-butylbenzyl)estra-1,3,5(10)-trienes: combination of two substituents at positions C3 and c17alpha of estradiol.
Laval University
Active site directed inhibition of estrone sulfatase by nonsteroidal coumarin sulfamates.
University Of Bath
Estrone sulfamates: potent inhibitors of estrone sulfatase with therapeutic potential.
University Of Bath
Inhibition of estrone sulfatase (ES) by alkyl and cycloalkyl ester derivatives of 4-[(aminosulfonyl)oxy] benzoic acid.
Kingston University
2-Alkylsulfanyl estrogen derivatives: synthesis of a novel class of multi-targeted anti-tumour agents.
University Of Bath
The difluoromethylene group as a replacement for the labile oxygen in steroid sulfates: a new approach to steroid sulfatase inhibitors.
University Of Waterloo
6-(2-adamantan-2-ylidene-hydroxybenzoxazole)-O-sulfamate: a potent non-steroidal irreversible inhibitor of human steroid sulfatase.
Novartis Forschungsinstitut
The mechanism of the irreversible inhibition of estrone sulfatase (ES) through the consideration of a range of methane- and amino-sulfonate-based compounds.
Kingston University
Inhibition of estrone sulfatase (ES) by derivatives of 4-[(aminosulfonyl)oxy] benzoic acid.
Kingston University
4,4'-Benzophenone-O,O'-disulfamate: a potent inhibitor of steroid sulfatase.
Novartis Research Institute Vienna
Design, synthesis and biochemical evaluation of AC ring mimics as novel inhibitors of the enzyme estrone sulfatase (ES).
Kingston University
A novel type of nonsteroidal estrone sulfatase inhibitors.
Hans-Kn�Ll Institute Of Natural Products Research
Acid dissociation constant, a potential physicochemical factor in the inhibition of the enzyme estrone sulfatase (ES).
Kingston University
Determination and use of a transition state for the enzyme estrone sulfatase (ES) from a proposed reaction mechanism.
Kingston University
Hydrophobicity, a physicochemical factor in the inhibition of the enzyme estrone sulfatase (ES).
Kingston University
Derivation of a possible transition-state for the reaction catalysed by the enzyme estrone Sulfatase (ES).
Kingston University
17 alpha-alkyl- or 17 alpha-substituted benzyl-17 beta-estradiols: a new family of estrone-sulfatase inhibitors.
Laval University
Phosphonates and thiophosphonates as sulfate surrogates: synthesis of estrone 3-methylthiophosphonate, a potent inhibitor of estrone sulfatase
TBA
17ß-Arylsulfonamides of 17ß-aminoestra-1,3,5(10)-trien-3-ol as highly potent inhibitors of steroid sulfatase.
University Of Waterloo
Inhibition of steroid sulfatase with 4-substituted estrone and estradiol derivatives.
University Of Waterloo
Hybrid Dual Aromatase-Steroid Sulfatase Inhibitors with Exquisite Picomolar Inhibitory Activity
TBA
3,17-disubstituted 2-alkylestra-1,3,5(10)-trien-3-ol derivatives: synthesis, in vitro and in vivo anticancer activity.
University Of Bath
Thiosemicarbazones of formyl benzoic acids as novel potent inhibitors of estrone sulfatase.
Institute For Natural Products Research And Infection Biology
2-substituted estradiol bis-sulfamates, multitargeted antitumor agents: synthesis, in vitro SAR, protein crystallography, and in vivo activity.
University Of Bath
A-ring-substituted estrogen-3-O-sulfamates: potent multitargeted anticancer agents.
University Of Bath
N-Acyl arylsulfonamides as novel, reversible inhibitors of human steroid sulfatase.
Novartis Institutes For Biomedical Research
Nortropinyl-arylsulfonylureas as novel, reversible inhibitors of human steroid sulfatase.
Novartis Research Institute Vienna
Design and synthesis of dansyl-labeled inhibitors of steroid sulfatase for optical imaging.
Chu De Qu£Bec - Research Center
A new series of aryl sulfamate derivatives: Design, synthesis, and biological evaluation.
University Of Sharjah
Synthesis and in vitro evaluation of piperazinyl-ureido sulfamates as steroid sulfatase inhibitors.
University Of Cagliari
Sulfamates in drug design and discovery: Pre-clinical and clinical investigations.
University Of Sharjah
Estrogen signaling: An emanating therapeutic target for breast cancer treatment.
Indian Institute Of Technology (Bhu)
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design.
Bristol-Myers Squibb
Synthesis and biological evaluation of fluorinated N-benzoyl and N-phenylacetoyl derivatives of 3-(4-aminophenyl)-coumarin-7-O-sulfamate as steroid sulfatase inhibitors.
Gdansk University Of Technology
First Dual Inhibitors of Steroid Sulfatase (STS) and 17?-Hydroxysteroid Dehydrogenase Type 1 (17?-HSD1): Designed Multiple Ligands as Novel Potential Therapeutics for Estrogen-Dependent Diseases.
Saarland University
URB602 inhibits monoacylglycerol lipase and selectively blocks 2-arachidonoylglycerol degradation in intact brain slices.
University Of California Irvine
Inverse in silico screening for identification of kinase inhibitor targets.
University Of Munich
Thermodynamics of the molecular and chiral recognition of cycloalkanols and camphor by modified beta-cyclodextrins possessing simple aromatic tethers.
Nankai University