PMID

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Article Title

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Design and Discovery of 2-Arylquinazolin-4-ones as Potent and Selective Inhibitors of Tankyrases.

University Of Bath

Optimization of benzoxazole-based inhibitors of Cryptosporidium parvum inosine 5'-monophosphate dehydrogenase.

Brandeis University

Dual inhibitors of inosine monophosphate dehydrogenase and histone deacetylase based on a cinnamic hydroxamic acid core structure.

University Of Minnesota

Selective and potent urea inhibitors of cryptosporidium parvum inosine 5'-monophosphate dehydrogenase.

Brandeis University

Penicacids A-C, three new mycophenolic acid derivatives and immunosuppressive activities from the marine-derived fungus Penicillium sp. SOF07.

Chinese Academy Of Sciences

Structure-activity relationship study of selective benzimidazole-based inhibitors of Cryptosporidium parvum IMPDH.

Brandeis University

Triazole inhibitors of Cryptosporidium parvum inosine 5'-monophosphate dehydrogenase.

Brandeis University

Novel mycophenolic adenine bis(phosphonate) analogues as potential differentiation agents against human leukemia.

Pharmasset

Discovery of N-[2-[2-[[3-methoxy-4-(5-oxazolyl)phenyl]amino]-5-oxazolyl]phenyl]-N-methyl-4- morpholineacetamide as a novel and potent inhibitor of inosine monophosphate dehydrogenase with excellent in vivo activity.

TBA

Synthesis of a methylenebis(phosphonate) analogue of mycophenolic adenine dinucleotide: a glucuronidation-resistant MAD analogue of NAD.

Codon Pharmaceuticals

Isosteric analogues of nicotinamide adenine dinucleotide derived from furanfurin, thiophenfurin, and selenophenfurin as mammalian inosine monophosphate dehydrogenase (type I and II) inhibitors.

Universit£

Synthesis of nonhydrolyzable analogues of thiazole-4-carboxamide and benzamide adenine dinucleotide containing fluorine atom at the C2' of adenine nucleoside: induction of K562 differentiation and inosine monophosphate dehydrogenase inhibitory activity.

Codon Pharmaceuticals

Rationally designed inhibitors of inosine monophosphate dehydrogenase.

University Of Chicago

The design, synthesis and in vitro immunosuppressive evaluation of novel isobenzofuran derivatives.

Shenyang Pharmaceutical University

Aminothiazoles as¿-secretase modulators.

F. Hoffmann-La Roche

Cofactor-type inhibitors of inosine monophosphate dehydrogenase via modular approach: targeting the pyrophosphate binding sub-domain.

University Of Minnesota

Structure-activity relationships for inhibition of inosine monophosphate dehydrogenase and differentiation induction of K562 cells among the mycophenolic acid derivatives.

Hokkaido University

Triazole-linked inhibitors of inosine monophosphate dehydrogenase from human and Mycobacterium tuberculosis.

University Of Minnesota

Mycophenolic acid analogs with a modified metabolic profile.

University Of Minnesota

Bis(sulfonamide) isosters of mycophenolic adenine dinucleotide analogues: inhibition of inosine monophosphate dehydrogenase.

University Of Minnesota

Dual inhibitors of inosine monophosphate dehydrogenase and histone deacetylases for cancer treatment.

University Of Minnesota

Methylenebis(sulfonamide) linked nicotinamide adenine dinucleotide analogue as an inosine monophosphate dehydrogenase inhibitor.

University Of Minnesota

Novel methylenephosphophosphonate analogues of mycophenolic adenine dinucleotide. Inhibition of inosine monophosphate dehydrogenase.

University Of Minnesota

Phosphonic acid-containing analogues of mycophenolic acid as inhibitors of IMPDH.

Gilead Sciences

Novel indole inhibitors of IMPDH from fragments: synthesis and initial structure-activity relationships.

Ucb Pharma

Low molecular weight indole fragments as IMPDH inhibitors.

Ucb Pharma

Novel 7-methoxy-6-oxazol-5-yl-2,3-dihydro-1H-quinazolin-4-ones as IMPDH inhibitors.

Ucb Pharma

Quinazolinethiones and quinazolinediones, novel inhibitors of inosine monophosphate dehydrogenase: synthesis and initial structure-activity relationships.

Celltech R And D

3-cyanoindole-based inhibitors of inosine monophosphate dehydrogenase: synthesis and initial structure-activity relationships.

Bristol-Myers Squibb Pharmaceutical Research Institute

Inhibitors of inosine monophosphate dehydrogenase: SARs about the N-[3-Methoxy-4-(5-oxazolyl)phenyl moiety.

Bristol-Myers Squibb Pharmaceutical Research Institute

Identification of novel and potent isoquinoline aminooxazole-based IMPDH inhibitors.

Bristol-Myers Squibb Pharmaceutical Research Institute

Novel indole-based inhibitors of IMPDH: introduction of hydrogen bond acceptors at indole C-3.

Bristol-Myers Squibb Pri

Quinolone-based IMPDH inhibitors: introduction of basic residues on ring D and SAR of the corresponding mono, di and benzofused analogues.

Bristol-Myers Squibb Pri

Novel inhibitors of IMPDH: a highly potent and selective quinolone-based series.

Bristol-Myers Squibb Pri

The TosMIC approach to 3-(oxazol-5-yl) indoles: application to the synthesis of indole-based IMPDH inhibitors.

Bristol-Myers Squibb Pharmaceutical Research Institute

A survey of cyclic replacements for the central diamide moiety of inhibitors of inosine monophosphate dehydrogenase.

Bristol-Myers Squibb Pharmaceutical Research Institute

Novel guanidine-based inhibitors of inosine monophosphate dehydrogenase.

Bristol-Myers Squibb Pharmaceutical Research Institute

Novel amide-based inhibitors of inosine 5'-monophosphate dehydrogenase.

Bristol-Myers Squibb Pri

Rapid synthesis of triazine inhibitors of inosine monophosphate dehydrogenase.

Bristol-Myers Squibb Pharmaceutical Research Institute

Novel diamide-based inhibitors of IMPDH.

Bristol-Myers Squibb Pharmaceutical Research Institute

Structure-activity relationships for inhibition of inosine monophosphate dehydrogenase by nuclear variants of mycophenolic acid.

Syntex Research