PMID

Data

Article Title

Organization

Design of selective Cathepsin inhibitors.

Astrazeneca

Evaluation of synthetic acridones and 4-quinolinones as potent inhibitors of cathepsins L and V.

Universidade Federal De S£O Carlos

Grassystatins A-C from marine cyanobacteria, potent cathepsin E inhibitors that reduce antigen presentation.

University Of Florida

The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin K.

Merck Frosst Centre For Therapeutic Research

Acridone alkaloids as potent inhibitors of cathepsin V.

Universidade Federal De S£O Carlos

1H-imidazo[4,5-c]pyridine-4-carbonitrile as cathepsin S inhibitors: separation of desired cellular activity from undesired tissue accumulation through optimization of basic nitrogen pka.

Merck Research Laboratories

Identification of potent and reversible cruzipain inhibitors for the treatment of Chagas disease.

Merck Research Laboratories

Trifluoromethylphenyl as P2 for ketoamide-based cathepsin S inhibitors.

Merck Research Laboratories

MK-7009, a potent and selective inhibitor of hepatitis C virus NS3/4A protease.

Merck Research Laboratories

Bicyclic carbamates as inhibitors of papain-like cathepsin proteases.

The Genomics Institute Of The Novartis Research Foundation

P2-P3 conformationally constrained ketoamide-based inhibitors of cathepsin K.

Glaxosmithkline

A structural screening approach to ketoamide-based inhibitors of cathepsin K.

Glaxosmithkline

Natural dimers of coumarin, chalcones, and resveratrol and the link between structure and pharmacology.

Nagasaki International University

The marine cyanobacterial metabolite gallinamide A is a potent and selective inhibitor of human cathepsin L.

University Of California

Repurposing a Library of Human Cathepsin L Ligands: Identification of Macrocyclic Lactams as Potent Rhodesain and Trypanosoma brucei Inhibitors.

Eth Zurich

RS-127445: a selective, high affinity, orally bioavailable 5-HT2B receptor antagonist.

Roche Bioscience