36 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Article Title
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Development of a potent 2-oxoamide inhibitor of secreted phospholipase A2 guided by molecular docking calculations and molecular dynamics simulations.
National And Kapodistrian University Of Athens
Identification of inhibitors against interaction between pro-inflammatory sPLA2-IIA protein and integrinavß3.
University Of California
Optimization of 5-hydroxytryptamines as dual function inhibitors targeting phospholipase A2 and leukotriene A4 hydrolase.
Peking University
A new cacospongionolide inhibitor of human secretory phospholipase A2 from the Tyrrhenian sponge Fasciospongia cavernosa and absolute configuration of cacospongionolides.
Istituto Per La Chimica Di Molecole Di Interesse Biologico Cnr
Synthesis and comparison of the antiinflammatory activity of manoalide and cacospongionolide B analogues.
Universit£
Quinoline-4-methyl esters as human nonpancreatic secretory phospholipase A2 inhibitors.
Peking University
Inhibition of secreted phospholipases A2 by 2-oxoamides based ona-amino acids: Synthesis, in vitro evaluation and molecular docking calculations.
University Of Athens
Design of new potent and selective secretory phospholipase A(2) inhibitors. 6-Synthesis, structure-activity relationships and molecular modelling of 1-substituted-4-[4,5-dihydro-1,2,4-(4H)-oxadiazol-5-one-3-yl(methyl)]-functionalized aryl piperazin/one/dione derivatives.
Universit£
Analogs of the marine natural product scalaradial lacking the α,β-unsaturated aldehyde: effects on human synovial fluid phospholipase A2 and macrophage lipid mediator production
TBA
Discovery of multitarget inhibitors by combining molecular docking with common pharmacophore matching.
Peking University
Simplified YM-26734 inhibitors of secreted phospholipase A2 group IIA.
University Of Washington
Highly specific and broadly potent inhibitors of mammalian secreted phospholipases A2.
University Of Washington
New sesquiterpene derivatives from the sponge Dysidea species with a selective inhibitor profile against human phospholipase A2 and other leukocyte functions.
Università
Inhibition of secreted phospholipase A2. 4-glycerol derivatives of 4,5-dihydro-3-(4-tetradecyloxybenzyl)-1,2,4-4H-oxadiazol-5-one with broad activities.
Université
The first potent inhibitor of mammalian group X secreted phospholipase A2: elucidation of sites for enhanced binding.
University Of Washington
Novel 3-dodecanoylindole-2-carboxylic acid inhibitors of cytosolic phospholipase A(2).
University Of MüNster
Synthesis and enzyme inhibitory activities of a series of lipidic diamine and aminoalcohol derivatives on cytosolic and secretory phospholipases A2.
Univ. De Valencia
1-(2-Hydroxybenzoyl)-thiosemicarbazides are promising antimicrobial agents targeting d-alanine-d-alanine ligase in bacterio.
Universit£
Synthesis and PLA2-inhibitory properties of 2(R)-acetamido-alkylphosphomethanols with a variable aggregate anchor.
Tumor Biology Center
Design and synthesis of new secretory phospholipase A2 inhibitor of a phospholipid analog.
Kwansei Gakuin University
Indole inhibitors of human nonpancreatic secretory phospholipase A2. 1. Indole-3-acetamides.
Eli Lilly
Indole inhibitors of human nonpancreatic secretory phospholipase A2. 3. Indole-3-glyoxamides.
Eli Lilly
Indole inhibitors of human nonpancreatic secretory phospholipase A2. 2. Indole-3-acetamides with additional functionality.
Eli Lilly
N-(carboxymethyl)-N-[3,5-bis(decyloxy)-phenyl]glycine (Ro 23-9358): a potent inhibitor of secretory phospholipases A2 with antiinflammatory activity.
Roche Research Center