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36 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Development of a potent 2-oxoamide inhibitor of secreted phospholipase A2 guided by molecular docking calculations and molecular dynamics simulations.EBI
National And Kapodistrian University Of Athens
Identification of inhibitors against interaction between pro-inflammatory sPLA2-IIA protein and integrinavß3.EBI
University Of California
Optimization of 5-hydroxytryptamines as dual function inhibitors targeting phospholipase A2 and leukotriene A4 hydrolase.EBI
Peking University
A new cacospongionolide inhibitor of human secretory phospholipase A2 from the Tyrrhenian sponge Fasciospongia cavernosa and absolute configuration of cacospongionolides.EBI
Istituto Per La Chimica Di Molecole Di Interesse Biologico Cnr
Synthesis and comparison of the antiinflammatory activity of manoalide and cacospongionolide B analogues.EBI
Universit£
Synthesis and phospholipase A2 inhibitory activity of thielocin B3 derivatives.EBI
Shionogi
Quinoline-4-methyl esters as human nonpancreatic secretory phospholipase A2 inhibitors.EBI
Peking University
Inhibition of secreted phospholipases A2 by 2-oxoamides based ona-amino acids: Synthesis, in vitro evaluation and molecular docking calculations.EBI
University Of Athens
Design of new potent and selective secretory phospholipase A(2) inhibitors. 6-Synthesis, structure-activity relationships and molecular modelling of 1-substituted-4-[4,5-dihydro-1,2,4-(4H)-oxadiazol-5-one-3-yl(methyl)]-functionalized aryl piperazin/one/dione derivatives.EBI
Universit£
 
A simple synthesis of biaryl phospholipase A2 inhibitors: Probing hydrophobic effectsEBI
TBA
 
Analogs of the marine natural product scalaradial lacking the α,β-unsaturated aldehyde: effects on human synovial fluid phospholipase A2 and macrophage lipid mediator productionEBI
TBA
 
Vinylogous hydroxamic acids: 5-lipoxygenase inhibitorsEBI
TBA
Discovery of multitarget inhibitors by combining molecular docking with common pharmacophore matching.EBI
Peking University
Simplified YM-26734 inhibitors of secreted phospholipase A2 group IIA.EBI
University Of Washington
Highly specific and broadly potent inhibitors of mammalian secreted phospholipases A2.EBI
University Of Washington
New sesquiterpene derivatives from the sponge Dysidea species with a selective inhibitor profile against human phospholipase A2 and other leukocyte functions.EBI
Università
Inhibition of secreted phospholipase A2. 4-glycerol derivatives of 4,5-dihydro-3-(4-tetradecyloxybenzyl)-1,2,4-4H-oxadiazol-5-one with broad activities.EBI
Université
The first potent inhibitor of mammalian group X secreted phospholipase A2: elucidation of sites for enhanced binding.EBI
University Of Washington
Synthesis of phospholipase A2 inhibitory biflavonoids.EBI
Kangwon National University
Carbocyclic[g]indole inhibitors of human nonpancreatic s-PLA2.EBI
Eli Lilly
Novel 3-dodecanoylindole-2-carboxylic acid inhibitors of cytosolic phospholipase A(2).EBI
University Of MüNster
Discovery of AZD2716: A Novel Secreted Phospholipase AEBI
Astrazeneca
Synthesis and enzyme inhibitory activities of a series of lipidic diamine and aminoalcohol derivatives on cytosolic and secretory phospholipases A2.EBI
Univ. De Valencia
1-(2-Hydroxybenzoyl)-thiosemicarbazides are promising antimicrobial agents targeting d-alanine-d-alanine ligase in bacterio.EBI
Universit£
Synthesis and PLA2-inhibitory properties of 2(R)-acetamido-alkylphosphomethanols with a variable aggregate anchor.EBI
Tumor Biology Center
Design and synthesis of new secretory phospholipase A2 inhibitor of a phospholipid analog.EBI
Kwansei Gakuin University
Indole inhibitors of human nonpancreatic secretory phospholipase A2. 1. Indole-3-acetamides.EBI
Eli Lilly
Indole inhibitors of human nonpancreatic secretory phospholipase A2. 3. Indole-3-glyoxamides.EBI
Eli Lilly
Indole inhibitors of human nonpancreatic secretory phospholipase A2. 2. Indole-3-acetamides with additional functionality.EBI
Eli Lilly
N-(carboxymethyl)-N-[3,5-bis(decyloxy)-phenyl]glycine (Ro 23-9358): a potent inhibitor of secretory phospholipases A2 with antiinflammatory activity.EBI
Roche Research Center
Discovery of new non-phospholipid inhibitors of the secretory phospholipases A2.EBI
Fisons
Design of Selective sPLAEBI
Astrazeneca
Discovery of a Series of Indole-2 Carboxamides as Selective Secreted Phospholipase AEBI
Astrazeneca