21 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Article Title
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Bishomoisoprenoid triazole bisphosphonates as inhibitors of geranylgeranyl diphosphate synthase.
University Of Iowa
Potent Triazole Bisphosphonate Inhibitor of Geranylgeranyl Diphosphate Synthase.
University Of Iowa
Geranyl and neryl triazole bisphosphonates as inhibitors of geranylgeranyl diphosphate synthase.
University Of Iowa
Multitarget drug discovery for tuberculosis and other infectious diseases.
University Of Illinois At Urbana-Champaign
Design of potent bisphosphonate inhibitors of the human farnesyl pyrophosphate synthase via targeted interactions with the active site 'capping' phenyls.
Mcgill University
Design and synthesis of active site inhibitors of the human farnesyl pyrophosphate synthase: apoptosis and inhibition of ERK phosphorylation in multiple myeloma cells.
Mcgill University
Synthesis, chiral high performance liquid chromatographic resolution and enantiospecific activity of a potent new geranylgeranyl transferase inhibitor, 2-hydroxy-3-imidazo[1,2-a]pyridin-3-yl-2-phosphonopropionic acid.
University Of Southern California
Mono- and dialkyl isoprenoid bisphosphonates as geranylgeranyl diphosphate synthase inhibitors.
University Of Iowa
Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases.
Institute Of Biological Chemistry
Pivaloyloxymethyl-modified isoprenoid bisphosphonates display enhanced inhibition of cellular geranylgeranylation.
University Of Iowa
Lipophilic bisphosphonates are potent inhibitors of Plasmodium liver-stage growth.
National Institute Of Immunology
Synthesis and biological evaluation of a series of aromatic bisphosphonates.
University Of Iowa
Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates and diphosphates: a potential route to new bone antiresorption and antiparasitic agents.
University Of Illinois At Urbana-Champaign
Discovery of Lipophilic Bisphosphonates That Target Bacterial Cell Wall and Quinone Biosynthesis.
Chinese Academy Of Sciences
Farnesyl Pyrophosphate Synthase as a Target for Drug Development: Discovery of Natural-Product-Derived Inhibitors and Their Activity in Pancreatic Cancer Cells.
Tsinghua University
Unraveling the Prenylation-Cancer Paradox in Multiple Myeloma with Novel Geranylgeranyl Pyrophosphate Synthase (GGPPS) Inhibitors.
Mcgill University
Novel benzimidazole phosphonates as potential inhibitors of protein prenylation.
University Of Iowa
?-Methylation enhances the potency of isoprenoid triazole bisphosphonates as geranylgeranyl diphosphate synthase inhibitors.
University Of Iowa