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51 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Probing of primed and unprimed sites of calpains: Design, synthesis and evaluation of epoxysuccinyl-peptide derivatives as selective inhibitors.EBI
E£Tv£S Lor£Nd University (Elte)
Grassystatins A-C from marine cyanobacteria, potent cathepsin E inhibitors that reduce antigen presentation.EBI
University Of Florida
Design and synthesis of calpain inhibitory 6-pyridone 2-carboxamide derivatives.EBI
Kyung Hee University
Identification of 3-acetyl-2-aminoquinolin-4-one as a novel, nonpeptidic scaffold for specific calpain inhibitory activity.EBI
Ewha Womans University
Design and synthesis of 4-aryl-4-oxobutanoic acid amides as calpain inhibitors.EBI
Shenyang Pharmaceutical University
Protease inhibitors: current status and future prospects.EBI
University Of Queensland
D-amino acid containing, high-affinity inhibitors of recombinant human calpain I.EBI
Cephalon
Dipeptidyl aspartyl fluoromethylketones as potent caspase-3 inhibitors: SAR of the P2 amino acid.EBI
Maxim Pharmaceuticals
1,2-Benzothiazine 1,1-dioxide alpha-ketoamide analogues as potent calpain I inhibitors.EBI
Cephalon
Hydroxyoxazolidines as alpha-aminoacetaldehye equivalents: novel inhibitors of calpain.EBI
Hoechst Marion Roussel
Synthesis of cinnamoyl ketoamides as hybrid structures of antioxidants and calpain inhibitors.EBI
College Of Pharmacy Kyung Hee University
 
Subsite requirements for peptide aldehyde inhibitors of human calpain IEBI
TBA
 
Nonpeptidic inhibitors of recombinant human calpain IEBI
TBA
 
Oligopresentation of protease inhibitors with β-cyclodextrin as templateEBI
TBA
 
Xanthene derived potent nonpeptidic inhibitors of recombinant human calpain IEBI
TBA
 
Synthesis of cystamidin a (pyrrole-3-propanamide), a reported calpain inhibitorEBI
TBA
 
Characterization of a continuous fluorogenic assay for calpain I. Kinetic evaluation of peptide aldehydes, halomethyl ketones and (acyloxy)methyl ketones as inhibitors of the enzymeEBI
TBA
 
Inhibition of human erythrocyte calpain I by novel quinolinecarboxamidesEBI
TBA
Molecular design to enhance the penetration into the retina via ocular instillation.EBI
Senju Pharmaceutical
Design and synthesis of 4-quinolinone 2-carboxamides as calpain inhibitors.EBI
Kyung Hee University
Exploration of orally available calpain inhibitors 2: peptidyl hemiacetal derivatives.EBI
Senju Pharmaceutical
Novel dual inhibitors of calpain and lipid peroxidation with enhanced cellular activity.EBI
Institut Henri Beaufour
Synthesis and biological evaluation of chromone carboxamides as calpain inhibitors.EBI
Institute Of Science & Technology
Dipeptidyl aspartyl fluoromethylketones as potent caspase inhibitors: peptidomimetic replacement of the P2 alpha-amino acid by a alpha-hydroxy acid.EBI
Maxim Pharmaceuticals
Retro hydrazino-azapeptoids as peptidomimetics of proteasome inhibitors.EBI
Université
Novel dual inhibitors of calpain and lipid peroxidation.EBI
Institut Henri Beaufour
Benzoylalanine-derived ketoamides carrying vinylbenzyl amino residues: discovery of potent water-soluble calpain inhibitors with oral bioavailability.EBI
Abbott
Structure-activity relationship study and drug profile of N-(4-fluorophenylsulfonyl)-L-valyl-L-leucinal (SJA6017) as a potent calpain inhibitor.EBI
Senju Pharmaceutical
Discovery of phenyl alanine derived ketoamides carrying benzoyl residues as novel calpain inhibitors.EBI
Abbott
1,2-Benzothiazine 1,1-dioxide P(2)-P(3) peptide mimetic aldehyde calpain I inhibitors.EBI
Cephalon
Synthesis of a reported calpain inhibitor isolated from Streptomyces griseus.EBI
The University Of Tennessee Health Science Center
Potent peptide alpha-ketohydroxamate inhibitors of recombinant human calpain I.EBI
Cephalon
Discovery of Fluoromethylketone-Based Peptidomimetics as Covalent ATG4B (Autophagin-1) Inhibitors.EBI
Roche Pharma Research And Early Development
Synthesis and biological evaluation of novel piperidine carboxamide derived calpain inhibitors.EBI
Knoll
P2-achiral, P'-extended alpha-ketoamide inhibitors of calpain I.EBI
Cephalon
Discovery of ABT-957: 1-Benzyl-5-oxopyrrolidine-2-carboxamides as selective calpain inhibitors with enhanced metabolic stability.EBI
Abbvie Deutschland
P2-proline-derived inhibitors of calpain I.EBI
Cephalon
Selective inhibition of the chymotrypsin-like activity of the 20S proteasome by 5-methoxy-1-indanone dipeptide benzamides.EBI
Cv Therapeutics
Novel peptidyl phosphorus derivatives as inhibitors of human calpain I.EBI
Cephalon
Novel peptidyl alpha-keto amide inhibitors of calpains and other cysteine proteases.EBI
Georgia Institute Of Technology
Peptide alpha-keto ester, alpha-keto amide, and alpha-keto acid inhibitors of calpains and other cysteine proteases.EBI
Georgia Institute Of Technology
Stereospecific synthesis of peptidyl alpha-keto amides as inhibitors of calpain.EBI
Alkermes
C1 and N5 derivatives of cerpegin: synthesis of a new series based on structure-activity relationships to optimize their inhibitory effect on 20S proteasome.EBI
Yerevan State University
Discovery of potent calpain inhibitors based on the azolo-imidazolidenone scaffold.EBI
Universidad De Alcal£
Mitigating the Metabolic Liability of Carbonyl Reduction: Novel Calpain Inhibitors with P1' Extension.EBI
Abbvie Deutschland
An overview of benzo[b]thiophene-based medicinal chemistry.EBI
Jain University
Discovery of Novel and Highly Selective Inhibitors of Calpain for the Treatment of Alzheimer's Disease: 2-(3-Phenyl-1H-pyrazol-1-yl)-nicotinamides.EBI
Abbvie Deutschland
Covalent Modifiers: A Chemical Perspective on the Reactivity of?,?-Unsaturated Carbonyls with Thiols via Hetero-Michael Addition Reactions.EBI
University Of Pittsburgh