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21 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
22959556 57 Discovery and preclinical profile of teneligliptin (3-[(2S,4S)-4-[4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl]pyrrolidin-2-ylcarbonyl]thiazolidine): a highly potent, selective, long-lasting and orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes.EBI Mitsubishi Tanabe Pharma Corporation
22824762 39 Fused bicyclic heteroarylpiperazine-substituted L-prolylthiazolidines as highly potent DPP-4 inhibitors lacking the electrophilic nitrile group.EBI Mitsubishi Tanabe Pharma Corporation
21764322 33 Identification of 3-aminomethyl-1,2-dihydro-4-phenyl-1-isoquinolones: a new class of potent, selective, and orally active non-peptide dipeptidyl peptidase IV inhibitors that form a unique interaction with Lys554.EBI Takeda Pharmaceutical Co., Ltd
19217790 68 Medicinal chemistry approaches to the inhibition of dipeptidyl peptidase-4 for the treatment of type 2 diabetes.EBI Matrix Laboratories Limited
18039579 59 Design and synthesis of DPP-IV inhibitors lacking the electrophilic nitrile group.EBI Ono Pharmaceutical Co., Ltd
17113301 83 Lead optimization of [(S)-gamma-(arylamino)prolyl]thiazolidine focused on gamma-substituent: Indoline compounds as potent DPP-IV inhibitors.EBI Mitsubishi Pharma Corporation
15713382 16 Synthesis and evaluation of pyrazolidine derivatives as dipeptidyl peptidase IV (DP-IV) inhibitors.EBI Korea Research Institute of Chemical Technology
15357972 30 Synthesis and DP-IV inhibition of cyano-pyrazoline derivatives as potent anti-diabetic agents.EBI Korea Research Institute of Chemical Technology
21324688 36 1-((3S,4S)-4-amino-1-(4-substituted-1,3,5-triazin-2-yl) pyrrolidin-3-yl)-5,5-difluoropiperidin-2-one inhibitors of DPP-4 for the treatment of type 2 diabetes.EBI Pfizer Inc
19275964 64 (3,3-Difluoro-pyrrolidin-1-yl)-[(2S,4S)-(4-(4-pyrimidin-2-yl-piperazin-1-yl)-pyrrolidin-2-yl]-methanone: a potent, selective, orally active dipeptidyl peptidase IV inhibitor.EBI Pfizer Inc
17317162 60 [(S)-gamma-(4-Aryl-1-piperazinyl)-l-prolyl]thiazolidines as a novel series of highly potent and long-lasting DPP-IV inhibitors.EBI Mitsubishi Pharma Corporation
16722626 94 cis-2,5-dicyanopyrrolidine inhibitors of dipeptidyl peptidase IV: synthesis and in vitro, in vivo, and X-ray crystallographic characterization.EBI Pfizer Inc
15863294 36 1-((S)-gamma-substituted prolyl)-(S)-2-cyanopyrrolidine as a novel series of highly potent DPP-IV inhibitors.EBI Mitsubishi Pharma Corporation
12801240 105 1-[[(3-hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine: a potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitor with antihyperglycemic properties.EBI Novartis Institute for BioMedical Research
12036346 12 1-[2-[(5-Cyanopyridin-2-yl)amino]ethylamino]acetyl-2-(S)-pyrrolidinecarbonitrile: a potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitor with antihyperglycemic properties.EBI TBA
15217282 4 First synthesis and determination of the absolute configuration of sulphostin, a novel inhibitor of dipeptidyl peptidase IV.EBI Microbial Chemistry Research Center
28442252 62 Approaches towards the development of chimeric DPP4/ACE inhibitors for treating metabolic syndrome.EBI Ranbaxy Laboratories Limited
9195869 28 Molecular recognition at the thrombin active site: structure-based design and synthesis of potent and selective thrombin inhibitors and the X-ray crystal structures of two thrombin-inhibitor complexes.BDB Laboratorium für Organische Chemie
19328688 12 Identification of an N-oxide pyridine GW4064 analog as a potent FXR agonist.BDB Roche R & D Center(China) Ltd