Search by Compound Name
Compounds Sorted by Binding Targets per Compound
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 2930 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55
56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 73 74 75 76 77 79 81 84 86 89 95
96 100 108 109 120 124 130 137 143 154 156 168 186 224 240 259 276 278 284 303
304 310 315 323 339 369 370 371 372 373 374 375 376 377 378 380 381 383 384
385 386 388 389 390 391 392 393 394 395 397 398 401 403 404 406 408 418 427
429 443 447 515
Compounds Sorted Alphabetically
Compound Name (alphabetical)
Binding Targets
Enz. Inhib. Data
ITC Data
Alternate Compound Names
- 3',5'-cyclic phosphodiesterase
- Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B
- Phosphodiesterase 4
- Phosphodiesterase 4A
- Phosphodiesterase 8
- Phosphodiesterase Type 10 (PDE10A)
- Phosphodiesterase Type 11 (PDE11A)
- Phosphodiesterase Type 2 (PDE2A)
- Phosphodiesterase Type 3 (PDE3B)
- Phosphodiesterase Type 4 (PDE4B)
- Phosphodiesterase Type 4 (PDE4D)
- Phosphodiesterase Type 5 (PDE5A)
- Phosphodiesterase Type 7 (PDE7B)
- Phosphodiesterase Type 9 (PDE9A)
- cAMP-specific 3',5'-cyclic phosphodiesterase 4A
- cAMP-specific 3',5'-cyclic phosphodiesterase 4B
- cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform 1
- cAMP-specific 3',5'-cyclic phosphodiesterase 4D
- 3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-methoxybenzamide
- 3-cyclopentyloxy-N-(3,5-dichloropyridin-4-yl)-4-methoxy-benzamide
- CHEMBL42126
- Cpodpmb
- Piclamilast
- RPR-73401
- 5-HT3A Serotonin Receptor
- 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 2A
- Acetylcholinesterase
- Amine oxidase (flavin-containing) A
- Amine oxidase [flavin-containing] B
- Bile salt export pump
- Canalicular multispecific organic anion transporter 1
- Canalicular multispecific organic anion transporter 2
- Cholinesterases
- Cytochrome P450 2B1
- D(1A) dopamine receptor
- D(2) dopamine receptor
- Monoamine Oxidase Type A (MAO-A)
- Monoamine Oxidase Type B (MAO-B)
- Monoamine oxidase
- Multidrug resistance-associated protein 4
- Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
- CHEMBL972
- DEPRENYL
- L-Deprenyl
- N-methyl-N-[(2R)-1-phenylpropan-2-yl]prop-2-yn-1-amine
- SLG
- Selegiline
- US8633208, Deprenyl
- US9469653, Selegiline
- methyl[(2R)-1-phenylpropan-2-yl]prop-2-yn-1-ylamine
- Androgen Receptor
- Androgen receptor/Baculoviral IAP repeat-containing protein 2
- Bile salt export pump
- Canalicular multispecific organic anion transporter 1
- Canalicular multispecific organic anion transporter 2
- Cytochrome P450
- Cytochrome P450 2C8
- Cytochrome P450 2C9
- Cytochrome P450 3A
- Estrogen receptor
- Glucocorticoid
- Glucocorticoid receptor
- Mineralocorticoid receptor
- Multidrug resistance-associated protein 4
- P-glycoprotein (P-gp)
- Progesterone receptor
- Thyroid hormone receptor alpha
- Thyroid hormone receptor beta
- (10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]-14-hydroxy-15-methyl-14-(prop-1-yn-1-yl)tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-1,6-dien-5-one
- Mifeprex
- Mifepristone
- RU-486
- RU486 (tetramethyl-rhodamine conjugated)
- 5-hydroxytryptamine receptor 2A
- ADORA1
- ADORA3
- Adenosine A1 receptor
- Adenosine A2 receptor
- Adenosine Receptors A2a (A2a)
- Adenosine receptor
- Adenosine receptor A1
- Adenosine receptor A1 (A1)
- Adenosine receptor A2a
- Adenosine receptor A2a and A3
- Adenosine receptor A2b
- Adenosine receptor A3
- Adenosine receptors; A2a & A2b
- Endoplasmin
- G protein-coupled receptor 80
- Sodium/nucleoside cotransporter 2
- Transmembrane domain-containing protein TMIGD3
- (2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
- Adenosine analog, 3
- Adenosine, N6-Ethyl-carboxamido
- Adenosine-5-(N-ethylcarboxamide)
- CHEMBL464859
- N-Ethylcarboxamidoadenosine
- NECA
- 5-HT3A Serotonin Receptor
- 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 2A
- D(1A) dopamine receptor
- D(2) dopamine receptor
- Dopamine transporter
- Monoamine transporter
- Monoamine transporters; Norepininephrine & dopamine
- Muscarinic acetylcholine receptor M1
- Norepinephrine Monoamine transporters
- Norepinephrine transporter
- Potassium voltage-gated channel subfamily H member 2
- Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
- Sigma non-opioid intracellular receptor 1
- Sodium channel protein type I I alpha subunit
- Sodium-dependent dopamine transporter
- Sodium-dependent noradrenaline transporter
- Sodium-dependent serotonin transporter
- Cocaine
- Cocaine (-)
- methyl (1R,2R,3S,5S)-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate
- methyl (1R,2R,3S,5S)-8-methyl-3-[(phenylcarbonyl)oxy]-8-azabicyclo[3.2.1]octane-2-carboxylate
- Adrenergic Alpha
- Aldehyde oxidase
- Cytochrome P450 3A
- HRH3
- Histamine H1 receptor
- Histamine H2 receptor
- Histamine H3 receptor
- Histamine H4 receptor
- Multidrug and toxin extrusion protein 1
- Multidrug and toxin extrusion protein 2
- P-glycoprotein (P-gp)
- P-glycoprotein 1
- P-glycoprotein 1 and 3 (MDR1a/MDR1b)
- Potassium-transporting ATPase alpha chain 1/beta chain
- Solute carrier family 22 member 11
- Solute carrier family 22 member 2
- Solute carrier family 22 member 6
- Solute carrier family 22 member 8
- (Cimetidine) N-Methyl-N''''-[2-(5-methyl-1H-imidazol-4-ylmethylsulfanyl)-ethyl]-guanidine,cyanide
- (Cimetidine)N-methyl-N-[2-(5-methyl-1H-4-imidazolylmethylsulfanyl)ethyl]cyanomethyliminomethanediamine
- (cimetidine) N-methyl-N-[2-(5-methyl-1H-4-imidazolylmethylsulfanyl)ethyl]cyanoiminomethanediamine
- 1-cyano-2-methyl-3-(2-((5-methyl-1H-imidazol-4-yl)methylthio)ethyl)guanidine
- 1-cyano-2-methyl-3-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine
- 2-Chloro-5-(1-hydroxy-3-oxo-2,3-dihydro-1H-isoindol-1-yl)-benzenesulfonamide(Cimetidine)
- 2-Methyl-8-phenethyl-imidazo[1,2-a]pyridine-3-carboxylic acid methyl ester(cimetidine)
- 2-methylamino-2-[2-(4-methyl-1H-5-imidazolylmethylsulfanyl)ethylamino]-(E)-1-imino cyanide
- 2-methylamino-2-[2-(5-methyl-1H-4-imidazolylmethylsulfanyl)ethylamino]-(Z)-1-imino cyanide(cimetidine)
- ; N''''''''-cyano-N-methyl-N''''-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)-ethyl)guanidine
- CHEMBL30
- CIMETIDINE
- Cimetidine
- Eureceptor
- N''''''''''''''''-cyano-N-methyl-N''''''''-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]thio}ethyl)guanidine
- N''''''''-cyano-N-methyl-N''''-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]-lambda~4~-sulfanyl}ethyl)guanidine
- N''''''''-cyano-N-methyl-N''''-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]thio}ethyl)guanidine
- N''''''''-cyano-N-methyl-N''''-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]thio}ethyl)guanidine (Cimetidine)
- N''''''''-cyano-N-methyl-N''''-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]thio}ethyl)guanidine(cimetidine)
- N''''''''-cyano-N-methyl-N''''-({[(5-methyl-1H-imidazol-4-yl)methyl]thio}methyl)guanidine(cimetidine)
- N-Cyano-N''''-methyl-N''''''''-(2-(((5-methyl-1H-imidazol-4-yl) methyl)thio)ethyl)guanidine(Cimetidine)
- N-Methyl-N''''-[2-(5-methyl-1H-imidazol-4-ylmethylsulfanyl)-ethyl]-N''''''''-Cyano-guanidine
- N-Methyl-N''''-[2-(5-methyl-1H-imidazol-4-ylmethylsulfanyl)-ethyl]-N''''''''-cyano-guanidine(Cimetidine)
- N-Methyl-N''''-[2-(5-methyl-1H-imidazol-4-ylmethylsulfanyl)-ethyl]-cyanoguanidine(cimetidine)
- N-cyanomethyl-N''''-methyl-N''''''''-[2-(5-methyl-1H-imidazol-4-ylmethylsulfanyl)-ethyl]-guanidine ( Cimetidine)
- N-methyl-N''''-cyano-N''''''''-[2-(5-methyl-1H-imidazol-4-ylmethylsulfanyl)-ethyl]-guanidine
- N-methyl-N-[2-(5-methyl-1H-4-imidazolylmethylsulfanyl)ethyl]-1-cyanoiminomethanediamine
- N-methyl-N-[2-(5-methyl-1H-4-imidazolylmethylsulfanyl)ethyl]cyanoiminomethanediamine (cimetidine)
- N-methyl-N-[2-(5-methyl-1H-4-imidazolylmethylsulfanyl)ethyl]imino(-N-cyano)methanediaminem
- N-tert-Butyl-N''''-[4-(1H-imidazol-4-yl)-phenyl]-formamidine(cimetidine)
- Tagamet
- Tagamet HB
- Tagamet hb 200
- cemitidine
- 72 kDa type IV collagenase
- Aminopeptidase
- Aminopeptidase B
- Aminopeptidase N
- Bacterial leucyl aminopeptidase
- Cystinyl aminopeptidase
- Cytosol aminopeptidase
- Dipeptidyl peptidase 4
- Gelatinase 2 (MMP-2)
- Histone deacetylase (HDAC1 and HDAC2)
- Leucine aminopeptidase
- Leucyl-cystinyl aminopeptidase
- Leukotriene A4 hydrolase
- Oligopeptide transporter small intestine isoform
- Oligopeptide transporter, kidney isoform
- Phospholipase A2, membrane associated
- Solute carrier family 15 member 1
- Zinc aminopeptidase
- (2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanamido]-4-methylpentanoic acid
- Bestatin
- CHEMBL29292
- Ubenimex
- 5-hydroxytryptamine receptor 1B
- 5-hydroxytryptamine receptor 1D
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 2B
- 5-hydroxytryptamine receptor 2C
- 5-hydroxytryptamine receptor 5A
- 5-hydroxytryptamine receptor 6
- 5-hydroxytryptamine receptor 7
- Adrenergic alpha1B
- Alpha-1A adrenergic receptor
- Alpha-2A adrenergic receptor
- Alpha-2B adrenergic receptor
- Alpha-2C adrenergic receptor
- D(1A) dopamine receptor
- D(2) dopamine receptor
- D(3) dopamine receptor
- Gamma-aminobutyric acid receptor subunit alpha-1
- Histamine H1 receptor
- US9481688, 1
- US9481688, 3
- 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 2A
- ADRB2
- Adrenergic receptor beta
- Alpha-1A adrenergic receptor
- Beta-1 adrenergic receptor
- Beta-2 adrenergic receptor
- Beta-3 adrenergic receptor
- Bile salt export pump
- Canalicular multispecific organic anion transporter 1
- Canalicular multispecific organic anion transporter 2
- Cytochrome P450 2J2
- D(2) dopamine receptor
- HTR2C
- Multidrug resistance-associated protein 4
- Serotonin (5-HT) receptor
- Serotonin 1B/1D receptor
- Squalene synthetase
- ALPRENOLOL,(+)
- ALPRENOLOL,(-)
- Alfeprol
- Alpheprol
- Alprenolol
- CHEMBL266195
- {2-hydroxy-3-[2-(prop-2-en-1-yl)phenoxy]propyl}(propan-2-yl)amine
- CDK2/CycE
- CDK2/Cyclin E/G1/S-specific cyclin E2
- CDK7/Cyclin H/MNAT1
- CaM Kinase II
- CaM kinase II
- Cyclic AMP-dependent protein kinase (PKA)
- Cyclin B/Cyclin-Dependent Kinase 1 (CDK1)/G2/mitotic-specific cyclin B2/G2/mitotic-specific cyclin B3
- Cyclin-Dependent Kinase 1 (CDK1)
- Cyclin-Dependent Kinase 2 (CDK2)
- Cyclin-Dependent Kinase 4 (CDK4)
- Cyclin-Dependent Kinase 5 (CDK5)
- Cyclin-Dependent Kinase 9 (CDK9)
- Epidermal growth factor receptor
- Protein kinase C (PKC)
- Protein kinase C alpha type
- cAMP-Dependent Protein Kinase (PKA)
- cAMP-dependent protein kinase (PKA)
- cAMP-dependent protein kinase catalytic subunit gamma
31 IC50
- 3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,22}]tricosa-1(16),2(10),4(9),5,7,11(15),17(22),18,20-nonaene-12,14-dione
- 6,7,12,13-Tetrahydro-5,7-dioxo-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole
- CHEMBL268368
- arcyriaflavin A
- 72 kDa type IV collagenase
- A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS-4)
- A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5)
- ADAM17
- ADAMTS1
- Collagenase 3
- Disintegrin and metalloproteinase domain-containing protein 10 (ADAM10)
- Disintegrin and metalloproteinase domain-containing protein 17
- Interstitial collagenase
- Matrix metalloproteinase 10
- Matrix metalloproteinase 15
- Matrix metalloproteinase 16
- Matrix metalloproteinase-12 (MMP12)
- Matrix metalloproteinase-14 (MMP14)
- Matrix metalloproteinase-7 (MMP7)
- Matrix metalloproteinase-9
- Neutrophil collagenase
- Stromelysin-1
- (3R,4R)-3-N-hydroxy-4-N-(4-{[2-(trifluoromethyl)-1H-1,3-benzodiazol-1-yl]methyl}benzene)oxane-3,4-diamido
- CHEMBL253275
- benzimidazole analog., 32
- α-Carbonic anhydrase (αCA)
- β-Carbonic anhydrase (βCA)
- Alpha carbonic anhydrase
- Alpha-carbonic anhydrase
- Astrosclerin-3
- Beta-carbonic anhydrase
- Carbonic Anhydrase VA
- Carbonic Anhydrase XIII
- Carbonic Anhydrase XV
- Carbonic anhydrase
- Carbonic anhydrase 1
- Carbonic anhydrase 2
- Carbonic anhydrase 4
- Carbonic anhydrase 6 (CA-VI)
- Carbonic anhydrase 7
- Carbonic anhydrase 9
- Carbonic anhydrase, alpha family
- Gamma-carbonic anhydrase
52 Ki
- BROMIDE
- Br-
- CHEMBL11685
- CHEMBL1644030
- CHEMBL1644694
- bromide
- bromide ion
- α-Carbonic anhydrase (αCA)
- β-Carbonic anhydrase (βCA)
- Alpha carbonic anhydrase
- Alpha-carbonic anhydrase
- Astrosclerin-3
- Beta-carbonic anhydrase
- Carbonic Anhydrase VA
- Carbonic Anhydrase XIII
- Carbonic Anhydrase XV
- Carbonic anhydrase
- Carbonic anhydrase 1
- Carbonic anhydrase 2
- Carbonic anhydrase 4
- Carbonic anhydrase 6 (CA-VI)
- Carbonic anhydrase 7
- Carbonic anhydrase 9
- Carbonic anhydrase, alpha family
- Gamma-carbonic anhydrase
52 Ki
- CHEMBL1644695
- CHEMBL185537
- I-
- IODIDE
- POTASSIUM IODIDE
- iodide
- iodide ion
- α-Carbonic anhydrase (αCA)
- β-Carbonic anhydrase (βCA)
- Alpha carbonic anhydrase
- Alpha-carbonic anhydrase
- Astrosclerin-3
- Beta-carbonic anhydrase
- Carbonic Anhydrase XIV
- Carbonic Anhydrase XV
- Carbonic anhydrase
- Carbonic anhydrase 1
- Carbonic anhydrase 12
- Carbonic anhydrase 2
- Carbonic anhydrase 4
- Carbonic anhydrase 6 (CA-VI)
- Carbonic anhydrase 7
- Carbonic anhydrase 9
- Gamma-carbonic anhydrase
- beta-Carbonic Anhydrase
56 Ki
- CHEMBL364571
- PhAsO3H2
- benzenarsonic acid
- benzenearsonic acid
- phenylarsonic acid
- 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 2B
- 5-hydroxytryptamine receptor 2C
- 5-hydroxytryptamine receptor 6
- 5-hydroxytryptamine receptor 7
- Adrenergic receptor alpha
- Cytochrome P450 1A
- Cytochrome P450 2C19
- Cytochrome P450 2C9
- Cytochrome P450 2D6 (2D6)
- Cytochrome P450 3A
- D(1A) dopamine receptor
- D(2) dopamine receptor
- D(3) dopamine receptor
- D(4) dopamine receptor
- HTR6
- Serotonin (5-HT) receptor
- 5-chloro-N-[4-methoxy-3-(piperazin-1-yl)phenyl]-3-methyl-1-benzothiophene-2-sulfonamide hydrochloride
- CHEMBL431298
- SB 271046
- SB-271046
- 5-hydroxytryptamine receptor 1A
- Apoptosis regulator Bcl-2
- BCL-W
- Bcl-2-related protein A1
- Bile salt export pump
- D(2) dopamine receptor
- D(3) dopamine receptor
- DNA dC->dU-editing enzyme APOBEC-3G
- Dopamine receptor
- Induced myeloid leukemia cell differentiation protein Mcl-1
- Isoform Bcl-X(L)
- MPI protein
- Opioid receptor
- POsterior Segregation family member (pos-1)
- RecName: Full=Zinc finger protein mex-5
- Runt-Related Transcription Factor 1 Isoform AML1C
- Serotonin (5-HT) receptor
- eukaryotic translation initiation factor 4 gamma, 1 isoform 4
- (6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol;hydrate;hydrochloride
- APOMORPHINE HYDROCHLORIDE
- APOMORPHINE HYDROCHLORIDE HEMIHYDRATE
- MLS000069811
- SMR000059235
- cid_6852399
- Myosin light chain kinase, smooth muscle
- NAD-dependent deacetylase sirtuin 2
- PKC alpha and beta-2
- Polo-Like Kinase 3
- Polo-Like Kinase 4
- Protein Kinase C
- Protein kinase C (PKC)
- Protein kinase C alpha type
- Protein kinase C delta type
- Protein kinase C, gamma
- Serine/threonine-protein kinase D1
- Serine/threonine-protein kinase PLK1
- Serine/threonine-protein kinase PLK2
- Serine/threonine-protein kinase PLK4
- Tyrosine-Specific Protein Kinase
- Tyrosine-protein kinase BLK
- cAMP-Dependent Protein Kinase (PKA)
- cGMP-Dependent Protein Kinase
- 3-{23-methyl-14-oxo-3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,22}]tricosa-1(16),2(10),4(9),5,7,11(15),17,19,21-nonaen-3-yl}propanenitrile
- CHEMBL302449
- Go 6976
- Indolocarbazole deriv.
- 3',5'-cyclic phosphodiesterase
- Bile salt export pump
- Botulinum neurotoxin type A
- Canalicular multispecific organic anion transporter 1
- Canalicular multispecific organic anion transporter 2
- Carbonic anhydrase 15
- Heat shock protein HSP 90-alpha
- Histone deacetylase 1
- Histone deacetylase 2
- Histone deacetylase 4
- Histone deacetylase 5
- Histone deacetylase 7
- Histone deacetylase 8
- Histone deacetylase 9
- Kappa-type opioid receptor
- LAP4
- MEP2
- Multidrug resistance-associated protein 4
- CLIOQUINOL
- Clioquinol (CQ)
- TG2-36-2
- cid_2788
- Caspase-3
- DNA dC->dU-editing enzyme APOBEC-3G
- Glucose 6-phosphate dehydrogenase (G6PD)
- Lysine-specific demethylase 5B
- M18 aspartyl aminopeptidase
- MPI protein
- Mannose-6-phosphate isomerase
- Probable global transcription activator SNF2L2
- Procathepsin L
- eukaryotic translation initiation factor 4 gamma, 1 isoform 4
- glucose-6-phosphate dehydrogenase
- glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase
- hexokinase
- neutrophil cytosolic factor 1
- phosphatase, orphan 1
- phosphomannomutase 2
- probable DNA dC->dU-editing enzyme APOBEC-3A
- streptokinase A precursor
- 2-(4-methylphenyl)-1,2-benzisothiazol-3(2H)-one
- 2-(4-methylphenyl)-1,2-benzothiazol-3-one
- 2-(p-tolyl)-1,2-benzothiazol-3-one
- MLS000583746
- SMR000200989
- cid_935415
- DNA dC->dU-editing enzyme APOBEC-3G
- G protein signalling regulator 19
- Glucose 6-phosphate dehydrogenase (G6PD)
- MPI protein
- MSRA protein
- Mannose-6-phosphate isomerase
- RGS7
- Regulator of G-protein signaling 8
- eukaryotic translation initiation factor 4 gamma, 1 isoform 4
- glucose-6-phosphate dehydrogenase
- glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase
- hexokinase
- large T antigen
- neutrophil cytosolic factor 1
- phosphatase, orphan 1
- phosphomannomutase 2
- regulator of G-protein signaling 4
- regulator of G-protein signalling 16
- 3-(3-keto-1,2-benzothiazol-2-yl)-N,N-dimethyl-benzenesulfonamide
- MLS000773738
- N,N-dimethyl-3-(3-oxidanylidene-1,2-benzothiazol-2-yl)benzenesulfonamide
- N,N-dimethyl-3-(3-oxo-1,2-benzothiazol-2-yl)benzenesulfonamide
- SMR000364449
- cid_5040456
- Aurora kinase B
- Axin-1/Glycogen synthase kinase-3 beta
- CDK2/CycE
- Cytoplasmic tyrosine-protein kinase BMX
- Inhibitor of nuclear factor kappa-B kinase subunit epsilon
- Interleukin-1 receptor-associated kinase 1
- Interleukin-1 receptor-associated kinase 4
- Non-receptor tyrosine-protein kinase TYK2
- Nuclear receptor subfamily 2 group C member 2
- Serine/threonine-protein kinase TBK1
- Tyrosine-protein kinase BTK
- Tyrosine-protein kinase ITK/TSK
- Tyrosine-protein kinase JAK2
- Tyrosine-protein kinase JAK3
- Tyrosine-protein kinase Lck
- Tyrosine-protein kinase Lyn
- Tyrosine-protein kinase TEC
- Tyrosine-protein kinase TXK
19 IC50
- 5-Phenyl-N-(pyridin-2-ylmethyl)-2-(pyrimidin-5-yl)quinazolin-4-amine
- US10214511, Example 1
- Acetylcholinesterase
- Acid phosphatase (acpA)
- Adrenaline alpha1
- Adrenaline alpha2
- Bile salt export pump
- Canalicular multispecific organic anion transporter 1
- Canalicular multispecific organic anion transporter 2
- D(2) dopamine receptor
- DNA (cytosine-5)-methyltransferase 1 (DNMT1)
- Genome polyprotein
- Multidrug resistance-associated protein 4
- Muscarinic acetylcholine receptor M2
- Potassium voltage-gated channel subfamily H member 2
- Solute carrier family 22 member 1
- Solute carrier family 22 member 2
- Solute carrier family 22 member 3
- Solute carrier family 22 member 4
- Voltage-gated L-type calcium channel
- 4-amino-N-[2-(diethylamino)ethyl]benzamide;hydrochloride
- 4-azanyl-N-[2-(diethylamino)ethyl]benzamide;hydrochloride
- MLS000069436
- PROCAINAMIDE
- PROCAINAMIDE HYDROCHLORIDE
- SMR000059079
- cid_66068
- 3C-like protease
- Apurinic-apyrimidinic endonuclease 1 (APE-1)
- Axin-1/Glycogen synthase kinase-3 beta
- BZLF2
- DNA recombination protein RecA
- G-protein coupled receptor 55
- Lipoamide Dehydrogenase (Lpd)
- POsterior Segregation family member (pos-1)
- Pyruvate dehydrogenase (PDH)
- RecName: Full=Zinc finger protein mex-5
- Serine/threonine-protein kinase PLK1
- Sphingosine 1-phosphate receptor 2
- TCF4/beta-catenin
- Valosin-containing protein
- mothers against decapentaplegic homolog 3
- nuclear receptor corepressor 2 isoform 2
- photoreceptor-specific nuclear receptor
- tyrosyl-DNA phosphodiesterase 2
- 3-(4-Chloro-phenyl)-1,6-dimethyl-1H-pyrimido[5,4-e][1,2,4]triazine-5,7-dione
- 3-(4-chlorophenyl)-1,6-dimethyl-pyrimido[5,4-e][1,2,4]triazine-5,7-dione
- 3-(4-chlorophenyl)-1,6-dimethyl-pyrimido[5,4-e][1,2,4]triazine-5,7-quinone
- 3-(4-chlorophenyl)-1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7-dione
- MLS000523518
- SMR000122591
- US9073941, 603
- cid_460749
- 5-HT5B
- 5-hydroxytryptamine receptor 1B
- 5-hydroxytryptamine receptor 1D
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 2B
- 5-hydroxytryptamine receptor 2C
- 5-hydroxytryptamine receptor 3A
- 5-hydroxytryptamine receptor 4 (5-HT4)
- 5-hydroxytryptamine receptor 5A
- 5-hydroxytryptamine receptor 7
- HTR3A
- HTR4
- HTR5A
- Neuronal acetylcholine receptor
- Serotonin (5-HT) receptor
- Serotonin 3 receptor (5HT3)
- Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor
- Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
- (zacopride)4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide
- 4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide
- 4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide (Zacopride)
- 4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide(zacopride)
- CHEMBL18041
- HTR5A4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide
- ZACOPRIDE
- ZACOPRIDE,R
- ZACOPRIDE,RS
- ZACOPRIDE,S
- 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 1A (5HT1A)
- Adrenergic alpha1B
- Adrenergic receptor alpha-1
- Adrenergic receptor alpha-2
- Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor
- Alpha-1A adrenergic receptor
- Alpha-1D adrenergic receptor
- Bile salt export pump
- Cerebral cortex alpha adrenergic receptor
- D(2) dopamine receptor
- D(3) dopamine receptor
- D(4) dopamine receptor
- DRD1
- Serotonin 1B/1D receptor
- Serotonin 2 (5-HT2) receptor
- Serotonin 2a (5-HT2a) receptor
- adrenergic Alpha2
- 1,1-Dioxo-2-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-1,2-dihydro-1lambda*6*-benzo[d]isothiazol-3-one
- 1,1-Dioxo-2-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-1,2-dihydro-1lambda*6*-benzo[d]isothiazol-3-one (Ipsapirone)
- 1,1-Dioxo-2-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-1,2-dihydro-1lambda*6*-benzo[d]isothiazol-3-one(Ipsapirone)
- CHEMBL8412
- IPSAPIRONE
- α-Carbonic anhydrase (αCA)
- β-Carbonic anhydrase (βCA)
- Alpha-carbonic anhydrase
- Astrosclerin-3
- Beta-carbonic anhydrase
- Carbonic Anhydrase XIII
- Carbonic anhydrase
- Carbonic anhydrase 1
- Carbonic anhydrase 12
- Carbonic anhydrase 2
- Carbonic anhydrase 2, isoform A
- Carbonic anhydrase 4
- Carbonic anhydrase 7
- Carbonic anhydrase 9
- Cytochrome P450 2E1
- Gamma-carbonic anhydrase
- Histone-lysine N-methyltransferase EHMT1
- Protein G9a (G9a)
- CHEMBL107217
- Ditiocarb sodium
- Sodium salt of Diethyl-dithiocarbamic acid(DDC)
- US9180183, DDTC
- sodium N,N-diethyl-dithiocarbamate
- sodium diethyldithiocarbamate
- Arachidonate 5-lipoxygenase
- Carbonic anhydrase
- Carbonic anhydrase 2
- Carbonic anhydrases; II & IX
- Cereblon/Histone deacetylase 6
- Histone deacetylase 1
- Histone deacetylase 2
- Histone deacetylase 3
- Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)
- Histone deacetylase 4
- Histone deacetylase 5
- Histone deacetylase 7
- Histone deacetylase 8
- Histone deacetylase 9
- Indoleamine 2,3-dioxygenase
- Mandelate racemase (MR)
- PA/PB1
- Stromelysin-1
- BENZHYDROXAMIC ACID
- BENZOHYDROXAMATE
- CHEMBL16300
- N-Hydroxy-benzamide
- N-hydroxybenzamide
- benzoyl hydroxamic acid
- 1,3-beta-glucan synthase component GLS2
- Angiotensin II receptor (AT-1) type-1
- Bile acid transporter
- Bile salt export pump
- Bile salt export pump (BSEP)
- CDGSH iron-sulfur domain-containing protein 1
- CDGSH iron-sulfur domain-containing protein 2
- Canalicular multispecific organic anion transporter 2
- Free fatty acid receptor 1
- Multidrug resistance-associated protein 4
- Nuclear receptor coactivator 2 (aa 740-753)
- Nuclear receptor subfamily 4 group A member 2/Retinoic acid receptor RXR-alpha
- PPAR alpha/gamma
- Peroxisome proliferator-activated receptor
- Peroxisome proliferator-activated receptor alpha
- Peroxisome proliferator-activated receptor alpha (PPAR alpha)
- Peroxisome proliferator-activated receptor delta
- Peroxisome proliferator-activated receptor gamma
- Avandamet
- Avandaryl
- Avandia
- BRL-49653
- CHEBI:50122
- ROSIGLITAZONE
- Rosiglitazone
- US10744117, Compound Rosiglitazone
- US9562012, rosiglitazone
- ADRA1B
- Adrenergic Alpha
- Adrenergic alpha1B
- Adrenergic receptor
- Adrenergic receptor alpha-2
- Alpha adrenergic receptor 1A and 1B
- Alpha-1A adrenergic receptor
- Alpha-1D adrenergic receptor
- Alpha-2A adrenergic receptor
- Alpha-2B adrenergic receptor
- Alpha-2C adrenergic receptor
- Bile salt export pump
- Canalicular multispecific organic anion transporter 1
- Canalicular multispecific organic anion transporter 2
- Cerebral cortex alpha adrenergic receptor
- Multidrug resistance-associated protein 4
- Potassium voltage-gated channel subfamily H member 2
- adrenergic Alpha1
- 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)piperazine
- 6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)piperazin-1-yl]quinazolin-4-amine
- CHEMBL611
- TERAZOSIN
- Terazosine
- Aurora kinase A/Targeting protein for Xklp2
- Aurora kinase B
- Axin-1/Glycogen synthase kinase-3 beta
- Casein kinase I isoform alpha
- Epidermal growth factor receptor
- Insulin-like growth factor I receptor
- Mitogen-activated protein kinase 1
- Platelet-derived growth factor receptor alpha
- Protein kinase C alpha type
- RAC-alpha serine/threonine-protein kinase
- Serine/threonine-protein kinase Aurora-C
- Serine/threonine-protein kinase Nek1
- Serine/threonine-protein kinase PLK1
- Vascular endothelial growth factor receptor 1
- Vascular endothelial growth factor receptor 2
- Vascular endothelial growth factor receptor 3
- cAMP-dependent protein kinase (PKA)
- p21-Activated kinase 2 (PAK2)
- CHEMBL3361128
- 1,3-beta-glucan synthase component GLS2
- 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase
- 5-hydroxytryptamine receptor 1A
- Adrenergic receptor
- Alpha-2A adrenergic receptor
- D(2) dopamine receptor
- Muscarinic acetylcholine receptor M1
- Muscarinic acetylcholine receptor M1 and M3
- Muscarinic acetylcholine receptor M2 and M4
- Muscarinic acetylcholine receptor M2 and M5
- Muscarinic acetylcholine receptor M5
- NMDA receptor subunit 2C (GluN2C)
- P-glycoprotein 1
- Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor
- Sigma intracellular receptor 2
- Sigma non-opioid intracellular receptor 1
- Sigma-1 receptor
- Sigma-2 receptor
- 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-piperazine
- 1-cyclohexyl-4-(3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl)piperazine
- 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)propyl]piperazine
- 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine
- CHEMBL53325
- PB-28
- 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 2A
- Alpha-1A adrenergic receptor
- Beta-2 adrenergic receptor
- CCKBR
- Cholecystokinin receptor
- D(1A) dopamine receptor
- D(2) dopamine receptor
- GRIA3
- Gamma-aminobutyric acid receptor subunit alpha-1
- Histamine H1 receptor
- Kappa-type opioid receptor
- Mu-type opioid receptor
- Muscarinic acetylcholine receptor M1
- Muscarinic acetylcholine receptor M2
- Muscarinic acetylcholine receptor M3
- Sigma non-opioid intracellular receptor 1
- adrenergic Alpha2
- 1-[(R)-2-Oxo-1-(2-oxo-2-o-tolyl-ethyl)-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-3-m-tolyl-urea
- CHEMBL115121
- YM022
- YM022 Racemate
- Cytochrome P450 1A
- Cytochrome P450 2A6
- Cytochrome P450 2B6
- Cytochrome P450 2C19
- Cytochrome P450 2C8
- Cytochrome P450 2C9
- Cytochrome P450 2D6 (2D6)
- Cytochrome P450 2E1
- Cytochrome P450 3A
- MAP kinase p38
- Mast/stem cell growth factor receptor Kit
- Mitogen-activated protein kinase 10
- Mitogen-activated protein kinase 8
- Mitogen-activated protein kinase 9
- Non-receptor tyrosine-protein kinase TYK2
- Platelet-derived growth factor subunit B (PDGFB)
- Potassium voltage-gated channel subfamily H member 2
- c-Jun N-terminal kinase 3
- CHEMBL2144409
- Cholinergic, Nicotinic Alpha3Beta2
- DNA dC->dU-editing enzyme APOBEC-3G
- Neuronal acetylcholine receptor
- Neuronal acetylcholine receptor Alpha-3/Beta-2
- Neuronal acetylcholine receptor Alpha-3/Beta-4
- Neuronal acetylcholine receptor Alpha-4/Beta-2
- Neuronal acetylcholine receptor protein alpha-2/beta-2 subunit
- Neuronal acetylcholine receptor protein alpha-3/beta-2 subunit
- Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit
- Neuronal acetylcholine receptor protein alpha-4/beta-4 subunit
- Neuronal acetylcholine receptor protein alpha-7 subunit
- Neuronal acetylcholine receptor subunit alpha-2
- Neuronal acetylcholine receptor subunit alpha-3
- Neuronal acetylcholine receptor subunit alpha-4
- Neuronal acetylcholine receptor; alpha2/beta2
- Nicotinic Alpha-Bungarotoxin
- n-AChR
- probable DNA dC->dU-editing enzyme APOBEC-3A
- 1,1-Dimethyl-4-phenyl-piperazin-1-ium
- CHEMBL134752
- CHEMBL47814
- DMPP
- cid_5911
- 5-hydroxytryptamine receptor 1A (5HT1A)
- 5-hydroxytryptamine receptor 1D
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 2C
- 5-hydroxytryptamine receptor 3A
- 5-hydroxytryptamine receptor 5A
- 5-hydroxytryptamine receptor 6
- 5-hydroxytryptamine receptor 7
- Adrenergic alpha1B
- Alpha-1A adrenergic receptor
- Alpha-2A adrenergic receptor
- Alpha-2B adrenergic receptor
- Alpha-2C adrenergic receptor
- Beta-1 adrenergic receptor
- Beta-2 adrenergic receptor
- Muscarinic acetylcholine receptor M4
- Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit
- Serotonin 1B/1D receptor
18 Ki
- 3-(1-Methyl-4,5-dihydro-1H-imidazol-2-ylmethyl)-pyridine
- CHEMBL313631
- Cell division protein FtsI (Peptidoglycan synthetase)
- Cytochrome P450 1A
- Cytochrome P450 2C19
- Cytochrome P450 2C9
- Cytochrome P450 2D6 (2D6)
- Cytochrome P450 2J2
- Cytochrome P450 3A
- D-amino-acid oxidase
- Penicillin binding protein 2'
- Penicillin-binding protein
- Penicillin-binding protein 1A
- Penicillin-binding protein 2B
- Penicillin-binding protein 2x
- Penicillin-binding protein 3
- Peptidoglycan D,D-transpeptidase MrdA
- Solute carrier family 22 member 6
- Solute carrier family 22 member 8
- Voltage-gated L-type calcium channel
38 IC50
- CEFTRIAXONE
- CHEBI:29007
- Ceftriaxone
- 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 5A
- 5-hydroxytryptamine receptor 6
- 5-hydroxytryptamine receptor 7
- Adenosine receptor A3
- Adrenergic receptor alpha-1
- D(1A) dopamine receptor
- D(1B) dopamine receptor
- D(2) dopamine receptor
- D(3) dopamine receptor
- D(4) dopamine receptor
- Histamine H1 receptor
- Histamine H2 Receptor
- Mu-type opioid receptor
- Sigma non-opioid intracellular receptor 1
- Sodium-dependent dopamine transporter
- Voltage-gated L-type calcium channel
18 IC50
- 4-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperazine-1-carboxylic acid 2-(4-cyano-phenyl)-ethyl ester
- CHEMBL326263
- Bile salt export pump
- Canalicular multispecific organic anion transporter 1
- Canalicular multispecific organic anion transporter 2
- Cytochrome P450 2J2
- Multidrug resistance-associated protein 4
- Potassium channel protein TASK-1
- Potassium voltage-gated channel subfamily H member 2
- Sodium channel alpha subunit
- Sodium channel protein type 10 subunit alpha
- Sodium channel protein type 2 alpha subunit
- Sodium channel protein type 5 subunit alpha
- Sodium channel protein type 7 subunit alpha
- Sodium channel protein type 9 subunit alpha
- Sodium channel protein type I I alpha subunit
- Twik-RElated Potassium (K+) channel 1 (TREK1)
- Voltage-gated L-type calcium channel
- Voltage-gated sodium channel alpha subunit Nav1.1
- Voltage-gated sodium channel subunit alpha Nav1.8
- 1-(2,6-dimethylphenoxy)-2-propanolamine
- 1-(2,6-dimethylphenoxy)propan-2-amine
- 2-(2,6-Dimethyl-phenoxy)-1-methyl-ethylamine
- 2-(2,6-Dimethyl-phenoxy)-1-methyl-ethylamine(mexiletine)
- CHEMBL558
- MEXILETINE
- Mexitil
- 5-hydroxytryptamine receptor 1B
- 5-hydroxytryptamine receptor 1D
- 5-hydroxytryptamine receptor 2B
- 5-hydroxytryptamine receptor 2C
- 5-hydroxytryptamine receptor 3A
- 5-hydroxytryptamine receptor 6
- 5-hydroxytryptamine receptor 7
- Alpha-2A adrenergic receptor
- Alpha-2B adrenergic receptor
- Alpha-2C adrenergic receptor
- D(1A) dopamine receptor
- D(3) dopamine receptor
- Histamine H2 receptor
- Muscarinic acetylcholine receptor M5
- Serotonin (5-HT) receptor
- Sigma non-opioid intracellular receptor 1
- Sodium-dependent dopamine transporter
- Translocator protein
18 Ki
- CHEMBL3633757
- Aldose reductase
- Aldose reductase (AR)
- Beta amyloid A4 protein
- Estradiol 17-beta-dehydrogenase 2
- Human immunodeficiency virus type 1 integrase
- Hyaluronidase
- Induced myeloid leukemia cell differentiation protein Mcl-1
- Integrase
- Interstitial collagenase
- Lipoxygenase
- Matrix metalloproteinase-2 (MMP-2)
- Proto-oncogene tyrosine-protein kinase Src
- Reverse transcriptase
- Transcription factor AP-1
- Transthyretin
- Tyrosinase
- Tyrosine-protein kinase Fyn
- Tyrosine-protein kinase Lck
- (2R)-3-(3,4-dihydroxyphenyl)-2-[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyloxy]propanoic acid
- (R)-rosmarinic acid
- CHEMBL324842
- Rosmarinic acid, 2
- US10688093, Compound rosmarinic acid
- cid_5281792
- Calmodulin/Proto-oncogene tyrosine-protein kinase Src
- Casein kinase I delta
- Casein kinase I isoform delta
- Cereblon/BCR/ABL
- Ephrin type-B receptor 2
- Epidermal growth factor receptor
- LAP4
- Proto-oncogene tyrosine-protein kinase Src
- RPL19A
- Serine/threonine-protein kinase RIPK2
- Tyrosine-protein kinase ABL1
- Tyrosine-protein kinase CSK
- Tyrosine-protein kinase Fyn
- Tyrosine-protein kinase HCK
- Tyrosine-protein kinase JAK2
- Tyrosine-protein kinase LCK
- Tyrosine-protein kinase Lck
- Tyrosine-protein kinase ZAP-70
- 1-(tert-butyl)-3-(4-chlorophenyl)-4-aminopyrazolo[3,4-d]pyrimidine
- 1-tert-Butyl-3-(4-chloro-phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine
- 1-tert-butyl-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
- 4-Amino-5-(4-chlorophenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine
- 4-amino-5-(4-chlorophenyl)-7-(tert-butyl)pyrazolo[3,4-d]pyrimidine
- AG-1879
- CHEMBL406845
- PP2
- US10544104, Compound 146
- US10688093, Compound PP2 (Pfizer)
- US9765037, Compound 146
- cid_4878
- Cyclin-dependent kinase 1
- Cyclooxygenase-1 (COX-1)
- Cytochrome P450 1A
- Cytochrome P450 2C9
- Cytochrome P450 2D6 (2D6)
- Cytochrome P450 3A
- Epidermal growth factor receptor
- Epidermal growth factor receptor and ErbB2 (HER1 and HER2)
- Hepatocyte growth factor receptor
- Insulin-like growth factor I receptor
- MAP kinase p38
- Mast/stem cell growth factor receptor Kit
- Mitogen-activated protein kinase 8
- Mitogen-activated protein kinase 9
- Proto-oncogene tyrosine-protein kinase Src
- RAF proto-oncogene serine/threonine-protein kinase
- Tyrosine-protein kinase ABL1
- Vascular endothelial growth factor receptor 2
19 IC50
- 4-[5-(2-Cyclohexylamino-pyridin-4-yl)-4-(4-fluoro-phenyl)-oxazol-2-yl]-piperidin-4-ol
- CHEMBL121405
- Cyclin-dependent kinase 1
- Cyclooxygenase-1 (COX-1)
- Cytochrome P450 1A
- Cytochrome P450 2C9
- Cytochrome P450 2D6 (2D6)
- Cytochrome P450 3A
- Epidermal growth factor receptor
- Epidermal growth factor receptor and ErbB2 (HER1 and HER2)
- Hepatocyte growth factor receptor
- Insulin-like growth factor I receptor
- MAP kinase p38
- Mast/stem cell growth factor receptor Kit
- Mitogen-activated protein kinase 8
- Mitogen-activated protein kinase 9
- Proto-oncogene tyrosine-protein kinase Src
- RAF proto-oncogene serine/threonine-protein kinase
- Tyrosine-protein kinase ABL1
- Vascular endothelial growth factor receptor 2
19 IC50
- CHEMBL120185
- Cyclopentyl-{4-[2-(4-fluoro-phenyl)-5-(4-methyl-piperazin-1-yl)-imidazo[4,5-b]pyridin-1-yl]-pyrimidin-2-yl}-amine
- Cyclin-dependent kinase 1
- Cyclooxygenase-1 (COX-1)
- Cytochrome P450 1A
- Cytochrome P450 2C9
- Cytochrome P450 2D6 (2D6)
- Cytochrome P450 3A
- Epidermal growth factor receptor
- Epidermal growth factor receptor and ErbB2 (HER1 and HER2)
- Hepatocyte growth factor receptor
- Insulin-like growth factor I receptor
- MAP kinase p38
- Mast/stem cell growth factor receptor Kit
- Mitogen-activated protein kinase 8
- Mitogen-activated protein kinase 9
- Proto-oncogene tyrosine-protein kinase Src
- RAF proto-oncogene serine/threonine-protein kinase
- Tyrosine-protein kinase ABL1
- Vascular endothelial growth factor receptor 2
19 IC50
- 4-[1-(2-Cyclopentylamino-pyrimidin-4-yl)-2-(3-trifluoromethyl-phenyl)-5H-imidazol-4-yl]-1-methyl-piperidin-4-ol
- CHEMBL118258
- Bcl-2-like protein 11
- Coagulation factor VII/tissue factor
- Cyclooxygenase
- Cytochrome P450 19A1
- DNA topoisomerase I (Topo I)
- Fatty acid-binding protein 4 (FABP4)
- Fatty acid-binding protein 5 (FABP5)
- Fatty-acid amide hydrolase 1
- Lipoxygenase-1
- Liver fatty acid binding protein (human L-FABP T94T)
- Liver fatty acid binding protein (rat L-FABP)
- Peroxisome proliferator-activated receptor
- Prostaglandin G/H synthase (Cyclooxygenase-2)
- Protein-tyrosine phosphatase 1B
- Sterol O-acyltransferase 1
- Sterol O-acyltransferase, Soat
- Trypsin
- Vanilloid receptor
- (Z)-9-octadecenoic acid
- (Z)-Octadec-9-enoic acid
- CHEMBL8659
- OLEATE
- Octadec-9-enoic acid
- oleaic acid
- oleicacid
- 3-oxoacyl-acyl-carrier protein reductase
- 6-phosphogluconate dehydrogenase (6PGD)
- Apoptosis regulator Bcl-2/Bcl-2 homologous antagonist/killer
- Cannabinoid receptor 1
- Cannabinoid receptor 2
- Death-associated protein kinase 1
- ELAV-like protein 3
- Enoyl-ACP Reductase (FabI)
- Enoyl-acyl-carrier protein reductase
- Fatty acid synthase
- Genome polyprotein
- Glucose-6-phosphate 1-dehydrogenase
- Hepatocyte growth factor receptor
- Human immunodeficiency virus type 1 reverse transcriptase
- Mitogen-activated protein kinase 14
- Proteasome subunit beta type-1/beta type-5
- Solute carrier organic anion transporter family member 1B1 (OATP1B1)
- Solute carrier organic anion transporter family member 1B3 (OATP1B3)
- (-)-Epicatechin-3-gallate
- (-)-epicatechin 3-O-gallate
- (-)-epicatechin gallate
- (-)-epicatechingallate
- (-)epicatechingallate
- (2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate
- (2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxychroman-3-yl 3,4,5-trihydroxybenzoate
- 3,4,5-Trihydroxy-benzoic acid (2R,3R)-2-(3,4-dihydroxy-phenyl)-5,7-dihydroxy-chroman-3-yl ester
- 3,4,5-Trihydroxy-benzoic acid 2-(3,4-dihydroxy-phenyl)-5,7-dihydroxy-chroman-3-yl ester
- CHEMBL36327
- Epicatechin gallate
- Epicatechin-3-O-gallate
- α-galactosidase
- Alpha-L-fucosidase I
- Alpha-galactosidase A
- Alpha-galactosidase C
- Alpha-glucosidase A (α-Gal A)
- Beta-galactosidase
- Beta-glucosidase
- Beta-glucosidase A
- Ceramide glucosyltransferase
- Glycogen debranching enzyme
- Lactase-glycosylceramidase
- Lactase-phlorizin hydrolase
- Lysosomal alpha-glucosidase
- Maltase-glucoamylase
- Sucrase-isomaltase
- beta-Galactosidase (β-Gal)
- beta-Galactosidase (β-Gal)(I51T)
- beta-Galactosidase (β-Gal)(R201C)
- (2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol
- (2R,3S,4R,5S)-2-Hydroxymethyl-piperidine-3,4,5-triol
- 1-deoxygalactonojirimycin
- CHEMBL110458
- D-galacto-1-Deoxynojirimycin
- DGJ
- ALK tyrosine kinase receptor
- Aurora kinase A/Targeting protein for Xklp2
- Aurora kinase B
- Epidermal growth factor receptor
- Epithelial discoidin domain-containing receptor 1
- Hepatocyte growth factor receptor
- Mast/stem cell growth factor receptor Kit
- Platelet-derived growth factor receptor
- Proto-oncogene tyrosine-protein kinase Src
- Proto-oncogene tyrosine-protein kinase receptor Ret
- RAC-alpha serine/threonine-protein kinase
- Tyrosine-protein kinase ABL1
- Tyrosine-protein kinase Mer
- Tyrosine-protein kinase receptor FLT3
- Tyrosine-protein kinase receptor TYRO3
- Tyrosine-protein kinase receptor UFO
- Vascular endothelial growth factor receptor 2
- mTOR/FKBP12A/FKBP12B
28 IC50
- CHEMBL3809489
- 10 kDa chaperonin
- 3C-like proteinase (3CL-PRO)
- 60 kDa chaperonin
- Bile salt export pump
- Canalicular multispecific organic anion transporter 1
- Canalicular multispecific organic anion transporter 2
- Glutathione S-transferase (GST)
- Glutathione S-transferase E2
- Glutathione transferase (GST)
- Glutathione transferase omega 1
- HSP60/HSP10
- Multidrug resistance-associated protein 4
- Prostaglandin D Synthase
- Thiosulfate sulfurtransferase
- UDP-glucose 4-epimerase
- large T antigen
- perilipin-1
- perilipin-5
- (2,3-Dichloro-4-(2-methylene-1-oxobutyl)phenoxy)acetic acid
- CHEMBL456
- ETHACRYNIC ACID
- Edecrin
- Etacrinic acid
- Ethacrynate
- Hydromedin
- Methylenebutyrylphenoxyacetic acid
- [2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetic acid
- jm5b01461, Compound 72
- Alpha-chymotrypsin
- Carboxylesterase
- Cathepsin A (CTSA)
- Elastase 2A
- Leukocyte elastase
- Pancreatic elastase
- Rhomboid protease (AaROM)
- Rhomboid protease (AfROM)
- Rhomboid protease (BsYqgP)
- Rhomboid protease (EcGlpG)
- Rhomboid protease (HiGlpG)
- Rhomboid protease (MmRHBDL1)
- Rhomboid protease (MmRHBDL3)
- Rhomboid protease (PhROM)
- Rhomboid protease (PsAarA)
- Rhomboid protease (TmROM)
- Rhomboid protease (VcROM)
- TPA: Essential protein of the mitochondrial intermembrane space
19 IC50
- 3,4‐Dichloroisocoumarin (2)
- 3,4-Dichloro-isochromen-1-one
- 3,4-dichloro-1H-isochromen-1-one
- 3,4-dichloroisocoumarin
- CHEMBL24983
- cid_1609
- 1,3-beta-glucan synthase component GLS2
- Acetylcholinesterase
- Butyrylcholinesterase (BChE)
- Butyrylcholinesterase (BuChE)
- Cell division protein FtsZ
- Cholesterol esterase
- Cholinesterase
- Cholinesterases
- Cholinesterases; ACHE & BCHE
- Cytochrome P450 1B1
- Neuraminidase
- Potassium voltage-gated channel subfamily H member 2
- Prolyl endopeptidase
- Retinoic acid receptor RXR-alpha/gamma
- Reverse transcriptase
- SUMO/sentrin specific peptidase family member 8
- Sortase A (SrtA)
- Telomerase reverse transcriptase
- 3,4-dimethoxy-6,7-dihydro-[1,3]dioxolo[4,5-g]pyrido[2,1-a]isoquinolin-5-ylium
- 9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinolin-7-ylium
- 9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinolin-7-ylium chloride
- 9,10-dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinolin-7-ylium; chloride
- BERBERINE
- Berberinechloride
- CHEMBL12089
- berberine dimer
- cid_12456
- 5-hydroxytryptamine receptor 1D
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 2C
- 5-hydroxytryptamine receptor 4 (5-HT4)
- Adrenergic receptor alpha
- Alpha-1A adrenergic receptor
- Alpha-2A adrenergic receptor
- Alpha-2B adrenergic receptor
- Beta-1 adrenergic receptor
- Beta-2 adrenergic receptor
- D(1A) dopamine receptor
- D(2) dopamine receptor
- Muscarinic acetylcholine receptor M1
- Muscarinic acetylcholine receptor M2
- Muscarinic acetylcholine receptor M3
- Muscarinic acetylcholine receptor M4
- Serotonin 1a (5-HT1a) receptor
- Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor
18 Ki
- CHEMBL294649
- 12-Lipoxygenase (12-LOX)
- 3',5'-cyclic phosphodiesterase
- 7,8-dihydro-8-oxoguanine triphosphatase
- Arachidonate 15-lipoxygenase
- Cytochrome P450 19A1
- Fatty acid synthase
- Isocitrate dehydrogenase [NADP] cytoplasmic
- MAP/microtubule affinity-regulating kinase 4
- Neutral sphingomyelinase
- Nuclear factor NF-kappa-B
- Nuclear factor NF-kappa-B (NF-kB)
- Probable maltase-glucoamylase 2
- Protein-tyrosine phosphatase 1B
- Sialidase
- Sphingomyelin phosphodiesterase
- Stimulator of interferon genes protein
- beta-Hydroxyacyl-acyl carrier protein dehydratase (FtFabZ)
- beta-Hydroxyacyl-acyl carrier protein dehydratase (YpFabZ)
- 1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2-enyl)-xanthen-9-one
- 1,3,6-trihydroxy-7-methoxy-2,8-bis(3-methylbut-2-enyl)-9H-xanthen-9-one
- 1,3,6-trihydroxy-7-methoxy-2,8-diprenylxanthone
- CHEMBL323197
- Mangostin
- alpha-mangostin
- Aurora kinase B
- Cyclin-dependent kinase 1
- Fibroblast growth factor receptor 1
- MAP/microtubule affinity-regulating kinase 2
- Mast/stem cell growth factor receptor Kit
- Mitogen-activated protein kinase 1
- Protein kinase C delta type
- Protein kinase C, gamma
- Proto-oncogene tyrosine-protein kinase Src
- RAC-alpha serine/threonine-protein kinase
- Serine/threonine-protein kinase CHK2
- Serine/threonine-protein kinase Chk1/2
- Serine/threonine-protein kinase Sgk1
- Serine/threonine-protein kinase c-TAK1
- Tyrosine-protein kinase receptor FLT3
- Vascular endothelial growth factor receptor 1
- Vascular endothelial growth factor receptor 2
- cAMP-dependent protein kinase (PKA)
- 2-[3-(3-methoxy-4-nitrophenyl)-11-oxo-10,11-dihydro-5Hdibenzo[b,e][1,4]diazepin-8-yl]-N-[4-(4-morpholinyl)phenyl]acetamide
- CHEMBL395080
- Dipeptidyl peptidase 2 (DPP II)
- Dipeptidyl peptidase 4
- Dipeptidyl peptidase 8/9
- Dipeptidyl peptidase 9
- Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4)
- Dipeptidyl peptidase IV
- Dipeptidyl peptidase VIII
- Dipeptidyl peptidase-IV (DDP-4)
- Fibroblast activation protein (FAP)
- Fibroblast activation protein alpha
- Lysosomal phospholipase A1
- Muscarinic acetylcholine receptor M1
- POU domain, class 2, transcription factor 1
- POU domain, class 2, transcription factor 2
- Potassium voltage-gated channel subfamily H member 2
- Prolyl endopeptidase
- Solute carrier family 22 member 8
- Solute carrier organic anion transporter family member 1B1 (OATP1B1)
- (R)-8-(3-aminopiperidin-1-yl)-7-(but-2-ynyl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione
- 8-[(3R)-3-Aminopiperidin-1-yl]-7-but-2-yn-1-yl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-3,7-dihydro-1H-purine-2,6-dione
- CHEMBL237500
- LINAGLIPTIN
- US10202383, Example 2(142)
- US10358449, Linagliptin
- US9255098, Linagliptin
- US9321791, 2(142)
- US9556175, 2(142)
- ALK tyrosine kinase receptor
- Ephrin type-A receptor 2
- Ephrin type-B receptor 2
- Epidermal growth factor receptor
- Fibroblast growth factor receptor 1
- Hepatocyte growth factor receptor
- Insulin-like growth factor I receptor
- Macrophage-stimulating protein receptor
- Mast/stem cell growth factor receptor Kit
- Platelet-derived growth factor receptor alpha
- Platelet-derived growth factor receptor beta
- Proto-oncogene tyrosine-protein kinase Src
- Proto-oncogene tyrosine-protein kinase receptor Ret
- Receptor protein-tyrosine kinase erbB-4
- Tyrosine-protein kinase ABL1
- Tyrosine-protein kinase receptor UFO
- Vascular endothelial growth factor receptor 1
- Vascular endothelial growth factor receptor 2
20 IC50
- CHEMBL4074262
- 5'-AMP-activated protein kinase subunit beta-1
- 5'-AMP-activated protein kinase subunit gamma-1
- 5'-AMP-activated protein kinase Complex 1
- 5'-AMP-activated protein kinase catalytic subunit alpha-2/beta-1/gamma-2
- 5'-AMP-activated protein kinase subunit gamma-2
- AMP-activated protein kinase alpha-1/beta-2/gamma-3
- AMP-activated protein kinase alpha-2/beta-2/gamma-2
- AMPK alpha1/beta1/gamma2
- AMPK alpha1/beta1/gamma3
- AMPK alpha1/beta2/gamma1
- AMPK alpha2/beta1/gamma1
- AMPK alpha2/beta2/gamma3
- Cytochrome P450 2D6
- Cytochrome P450 3A
- MAP kinase-activated protein kinase 5
- Nuclear receptor subfamily 1 group I member 2
- Prkaa1/Prkab2/Prkag1
- Transcription factor Dp-2
- CHEMBL4082745
- Cyclin-dependent kinase 2
- Cytochrome P450 2C9
- Ephrin type-B receptor 4
- Epidermal growth factor receptor
- Fibroblast growth factor receptor 1
- Focal adhesion kinase 1
- Insulin-like growth factor I receptor
- Macrophage colony-stimulating factor 1 receptor (CSF1R)
- Mitogen-activated protein kinase 14
- Mitogen-activated protein kinase 8
- PAK 1/CDC42
- Platelet-derived growth factor receptor beta
- Proto-oncogene tyrosine-protein kinase Src
- Serine/threonine-protein kinase Chk1/2
- Serine/threonine-protein kinase PLK1
- Tyrosine-protein kinase CSK
- Tyrosine-protein kinase JAK2
- Vascular endothelial growth factor receptor 2
18 IC50
- CHEMBL475817
- N-(6-amino-5-chloropyridin-3-yl)-2-chloro-5-(3-(trifluoromethyl)benzamido)benzamide
- Cytochrome P450 1A
- Cytochrome P450 2B6
- Cytochrome P450 2C19
- Cytochrome P450 2C8
- Cytochrome P450 2C9
- Cytochrome P450 2D6
- Cytochrome P450 3A
- Inward rectifier potassium channel 2
- Kv channel-interacting protein 2/Potassium voltage-gated channel subfamily D member 3
- L-type calcium channel alpha-1c/beta-2/alpha2delta-1
- Melanin-concentrating hormone receptor 2/HERG
- Metabotropic glutamate receptor
- Metabotropic glutamate receptor 5
- Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
- Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
- Sodium channel protein type 5 subunit alpha
- Voltage-dependent T-type calcium channel subunit alpha-1H
- Voltage-gated potassium channel
- CHEMBL2386850
- Axin-1/Glycogen synthase kinase-3 beta
- Cyclin-dependent kinase 2
- Hepatocyte growth factor receptor
- Interleukin-1 receptor-associated kinase 4
- Mitogen-activated protein kinase 1
- Mitogen-activated protein kinase 10
- Mitogen-activated protein kinase 14
- Mitogen-activated protein kinase kinase kinase 7
- Mitogen-activated protein kinase kinase kinase 8
- Protein kinase C theta type
- Proto-oncogene tyrosine-protein kinase Src
- Serine/threonine-protein kinase PLK1
- Tyrosine-protein kinase ITK/TSK
- Tyrosine-protein kinase JAK2
- Tyrosine-protein kinase JAK3
- Tyrosine-protein kinase SYK
- Tyrosine-protein kinase receptor FLT3
- Vascular endothelial growth factor receptor 2
18 Ki
- CHEMBL494221
- trans-4-(3-(3-(trifluoromethyl)phenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-ylamino)cyclohexanol
- 5'-AMP-activated protein kinase subunit beta-1
- ALK1
- ALK2
- ALK3
- ALK4
- ALK5
- AMP-activated protein kinase (AMPK)
- Activin receptor type-1
- Activin receptor type-1B
- Activin receptor-like kinase 3 (ALK-3)
- Bone morphogenetic protein
- Bone morphogenetic protein 4
- Bone morphogenetic protein receptor type-1B (BMPR1B) aa 168-495
- Bone morphogenetic protein receptor type-2
- Serine/threonine-protein kinase receptor R3
- TGF-beta receptor type II
- TGF-beta receptor type-1
- Vascular endothelial growth factor receptor 2
- 4-(6-(4-(piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline
- 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline
- CHEMBL513147
- LDN-193189
- Cyclin-dependent kinase 2
- Cytochrome P450 1A
- Cytochrome P450 2C19
- Cytochrome P450 2C9
- Cytochrome P450 2D6 (2D6)
- Cytochrome P450 3A
- Dual specificity mitogen-activated protein kinase kinase 1
- Epidermal growth factor receptor
- Heat shock protein beta-1
- Macrophage colony-stimulating factor 1 receptor (CSF1R)
- Mitogen-activated protein kinase 10
- Mitogen-activated protein kinase 11
- Mitogen-activated protein kinase 14
- Receptor protein-tyrosine kinase erbB-4
- Serine/threonine-protein kinase PLK1
- Serine/threonine-protein kinase Sgk1
- Tyrosine-protein kinase Lck
- Vascular endothelial growth factor receptor 2
- 6-Methyl-biphenyl-3,4'-dicarboxylic acid 3-cyclopropylamide 4'-cyclopropylmethyl-amide
- CHEMBL478649
- N3-cyclopropyl-N4'-(cyclopropylmethyl)-6-methylbiphenyl-3,4'-dicarboxamide
- N~3~-cyclopropyl-N~4~'-(cyclopropylmethyl)-6-methylbiphenyl-3,4'-dicarboxamide
- 5-HT3A Serotonin Receptor
- 5-HT5B
- 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 1B
- 5-hydroxytryptamine receptor 1D
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 6
- 5-hydroxytryptamine receptor 7
- Alpha-1A adrenergic receptor
- D(1A) dopamine receptor
- D(2) dopamine receptor
- D(3) dopamine receptor
- HTR1D
- HTR6
- Serotonin (5-HT) receptor
- Serotonin 1B/1D receptor
- Serotonin receptor 2a and 2b (5HT2A and 5HT2B)
- Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
32 Ki
- 50285557
- 7-Methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline-9-carboxylic acid ((2R,5S,10bS)-5-benzyl-10b-hydroxy-2-methyl-3,6-dioxo-octahydro-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl)-amide
- DHE
- Axin-1/Glycogen synthase kinase-3 beta
- Cyclin-Dependent Kinase 5 (CDK5)
- Cyclin-Dependent Kinase 7 (CDK7)
- Cyclin-Dependent Kinase 9 (CDK9)
- Dual specificity protein kinase CLK1
- Dual specificity protein kinase CLK2
- Dual specificity protein kinase CLK3
- Dual specificity protein kinase CLK4
- Dual specificity tyrosine-phosphorylation-regulated kinase 4
- Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
- Dual-specificity tyrosine-phosphorylation regulated kinase 1A
- Dual-specificity tyrosine-phosphorylation regulated kinase 2
- Dual-specificity tyrosine-phosphorylation regulated kinase 3
- Dual-specificity tyrosine-regulated kinases 1B
- ERK-2
- Glycogen synthase kinase-3
- Leukotriene B4 receptor
- Serine/threonine-protein kinase pim-1
- CHEMBL485053
- leucettamine B
- Aldose reductase (AR)
- Beta-secretase 1
- Carbonic Anhydrase III
- Carbonic Anhydrase VA
- Carbonic Anhydrase VB
- Carbonic Anhydrase XIII
- Carbonic Anhydrase XIV
- Carbonic anhydrase 1
- Carbonic anhydrase 12
- Carbonic anhydrase 15
- Carbonic anhydrase 2
- Carbonic anhydrase 4
- Carbonic anhydrase 6 (CA-VI)
- Carbonic anhydrase 7
- Carbonic anhydrase 9
- Cytochrome P450 19A1
- Exportin-1
- Sorbitol dehydrogenase
- 7-(methyloxy)-2H-chromen-2-one
- 7-Methoxycoumarin
- 7-methoxy-2H-1-benzopyran-2-one
- Ayapanin
- CHEMBL49732
- Herniarin
- Herniarine
- Methylumbelliferone
- 72 kDa type IV collagenase
- A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS-4)
- A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5)
- Collagenase 3
- Disintegrin and metalloproteinase domain-containing protein 17
- Interstitial collagenase
- Matrix metalloproteinase 15
- Matrix metalloproteinase 16
- Matrix metalloproteinase 26
- Matrix metalloproteinase-12 (MMP12)
- Matrix metalloproteinase-14 (MMP14)
- Matrix metalloproteinase-24
- Matrix metalloproteinase-25
- Matrix metalloproteinase-7 (MMP7)
- Matrix metalloproteinase-9
- Neutrophil collagenase
- Solute carrier family 22 member 8
- Stromelysin-1
- CHEMBL603656
- trans-4-((5-(2-(4-fluorobenzylcarbamoyl)-6-methylpyridin-4-yl)-2H-tetrazol-2-yl)methyl)cyclohexanecarboxylic acid
- Casein kinase I isoform epsilon
- Chaperone activity of bc1 complex-like, mitochondrial
- Cytochrome P450 1A
- Cytochrome P450 2C19
- Cytochrome P450 2C9
- Cytochrome P450 2D6 (2D6)
- Cytochrome P450 3A
- Epithelial discoidin domain-containing receptor 1
- Mitogen-activated protein kinase 10
- Mitogen-activated protein kinase 11
- Mitogen-activated protein kinase 14
- Mitogen-activated protein kinase 8
- Mitogen-activated protein kinase 9
- Ribosomal protein S6 kinase alpha 4
- Ribosomal protein S6 kinase alpha-3
- Serine/threonine protein kinase NLK
- Serine/threonine-protein kinase 36
- Serine/threonine-protein kinase GAK
- 6-(2,4-difluorophenoxy)-2-{[3-hydroxy-1-(2-hydroxyethyl)propyl]amino}-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one
- CHEMBL1090089
- pamapimod
- 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 3A
- Beta-1 adrenergic receptor
- Beta-2 adrenergic receptor
- Cytochrome P450 1A
- Cytochrome P450 2C19
- Cytochrome P450 2D6 (2D6)
- Cytochrome P450 3A
- D(1A) dopamine receptor
- D(2) dopamine receptor
- D(3) dopamine receptor
- Histamine H1 receptor
- Histamine H2 Receptor
- Histamine H3 receptor
- Histamine H4 receptor
- Muscarinic acetylcholine receptor M1
- Muscarinic acetylcholine receptor M3
- 2-(2-(4-tert-Butylphenylthio)ethyl)-1H-imidazole
- 4-(2-(4-tert-butylphenylthio)ethyl)-1H-imidazole
- CHEMBL1098230
- Angiopoietin-1 receptor
- Aurora kinase A/Targeting protein for Xklp2
- Axin-1/Glycogen synthase kinase-3 beta
- Epidermal growth factor receptor
- Fibroblast growth factor receptor 1
- Focal adhesion kinase 1
- Insulin receptor
- Insulin-like growth factor I receptor
- Mast/stem cell growth factor receptor Kit
- Mitogen-activated protein kinase 3
- Platelet-derived growth factor receptor alpha
- Platelet-derived growth factor receptor beta
- Protein kinase C theta type
- Proto-oncogene tyrosine-protein kinase Src
- Receptor tyrosine-protein kinase erbB-2
- Serine/threonine-protein kinase B-raf
- Vascular endothelial growth factor receptor 1
- Vascular endothelial growth factor receptor 2
- 1-(2-fluoro-4-(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yloxy)phenyl)-3-(3-(trifluoromethyl)phenyl)urea
- 1-{2-Fluoro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)-oxy]phenyl}-3-[3-(trifluoromethyl)phenyl]urea
- CHEMBL1254007
- CaM kinase IV
- Casein kinase I isoform delta
- Cyclin-dependent kinase 2
- Epidermal growth factor receptor
- Hepatocyte growth factor receptor
- Inhibitor of nuclear factor kappa-B kinase subunit beta
- Interleukin-1 receptor-associated kinase 4
- Mitogen-activated protein kinase 1
- Protein kinase C alpha type
- RAC-alpha serine/threonine-protein kinase
- Rho-associated protein kinase 2
- Ribosomal protein S6 kinase alpha-3
- Serine/threonine-protein kinase Chk1/2
- Serine/threonine-protein kinase PLK3
- Testis-specific serine/threonine-protein kinase 2
- Tyrosine-protein kinase JAK2
- Tyrosine-protein kinase Lck
- Vascular endothelial growth factor receptor 2
18 IC50
- 3-((R)-1-((2S,6R)-2,6-dimethylmorpholino)ethyl)-N-(6-methyl-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl)isothiazol-5-amine
- CHEMBL1270399
- Casein kinase I isoform epsilon
- Chaperone activity of bc1 complex-like, mitochondrial
- Cytochrome P450 1A
- Cytochrome P450 2C19
- Cytochrome P450 2C9
- Cytochrome P450 2D6 (2D6)
- Cytochrome P450 3A
- Epithelial discoidin domain-containing receptor 1
- Mitogen-activated protein kinase 10
- Mitogen-activated protein kinase 11
- Mitogen-activated protein kinase 14
- Mitogen-activated protein kinase 8
- Mitogen-activated protein kinase 9
- Ribosomal protein S6 kinase alpha 4
- Ribosomal protein S6 kinase alpha-3
- Serine/threonine protein kinase NLK
- Serine/threonine-protein kinase 36
- Serine/threonine-protein kinase GAK
- 6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-pyran-4-ylamino)pyrido[2,3-d]pyrimidin-7(8H)-one
- CHEMBL1230122
- Ephrin type-A receptor 2
- Ephrin type-B receptor 2
- Epidermal growth factor receptor
- Fibroblast growth factor receptor 1
- Fibroblast growth factor receptor 2
- Fibroblast growth factor receptor 3
- Fibroblast growth factor receptor 4
- Hepatocyte growth factor receptor
- Insulin-like growth factor I receptor
- Macrophage-stimulating protein receptor
- Mast/stem cell growth factor receptor Kit
- Platelet-derived growth factor receptor alpha
- Platelet-derived growth factor receptor beta
- Proto-oncogene tyrosine-protein kinase Src
- Proto-oncogene tyrosine-protein kinase receptor Ret
- Tyrosine-protein kinase ABL1
- Vascular endothelial growth factor receptor 1
- Vascular endothelial growth factor receptor 2
18 IC50
- CHEMBL1784725
- Ethyl 8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-carboxylate
- Cytochrome P450 1A
- Cytochrome P450 2A6
- Cytochrome P450 2C19
- Cytochrome P450 2C8
- Cytochrome P450 2C9
- Cytochrome P450 2D6 (2D6)
- Cytochrome P450 3A
- Dipeptidyl peptidase 2 (DPP II)
- Dipeptidyl peptidase 4
- Dipeptidyl peptidase 9
- Dipeptidyl peptidase VIII
- Fibroblast activation protein alpha
- Membrane-bound aminopeptidase P (APP2)
- Muscarinic acetylcholine receptor M1
- Muscarinic acetylcholine receptor M2
- Muscarinic acetylcholine receptor M4
- Potassium voltage-gated channel subfamily H member 2
- Prolyl endopeptidase
18 IC50
- CHEMBL1819090
- Apoptosis Signal-regulating Kinase 1 (ASK1)
- Aurora kinase A/Targeting protein for Xklp2
- Axin-1/Glycogen synthase kinase-3 beta
- Cyclin-dependent kinase 2
- Epidermal growth factor receptor
- Inhibitor of nuclear factor kappa-B kinase subunit beta
- Insulin receptor
- Mitogen-activated protein kinase 8
- PAK 1/CDC42
- RAC-alpha serine/threonine-protein kinase
- Rho-associated protein kinase 1
- Serine/threonine-protein kinase AKT2
- TGF-beta receptor type-1
- Tyrosine-protein kinase ITK/TSK
- Tyrosine-protein kinase Lck
- Tyrosine-protein kinase SYK
- Vascular endothelial growth factor receptor 2
- [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial
21 IC50
- CHEMBL1957085
- 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 2B
- 5-hydroxytryptamine receptor 2C
- 5-hydroxytryptamine receptor 5A
- Adrenergic receptor alpha
- Alpha adrenergic receptor (1a and 1d)
- Alpha-1A adrenergic receptor
- Alpha-2A adrenergic receptor
- Alpha-2B adrenergic receptor
- D(3) dopamine receptor
- Histamine H1 receptor
- Histamine H2 receptor
- Histamine H3 receptor
- Muscarinic acetylcholine receptor M2 and M4
- Muscarinic acetylcholine receptor M5
- Sigma intracellular receptor 2
- Sigma-1 receptor
18 Ki
- CHEMBL4165863
- B-RAF V600E
- EGFR (G719S)
- EGFR (L861Q)
- Epidermal growth factor receptor
- Epidermal growth factor receptor (EGFR)(G719C)
- Epidermal growth factor receptor (EGFR)(del 747-749)(A750P)
- Epidermal growth factor receptor (EGFR)(del 747-752)(P753S)
- Epidermal growth factor receptor (EGFR)(del 752-759)
- Epidermal growth factor receptor (T790M)
- Epidermal growth factor receptor(L858R)
- Epidermal growth factor receptor(L858R, T790M)
- Misshapen-like kinase 1 (MINK1)
- Proto-oncogene tyrosine-protein kinase Src
- Serine/threonine-protein kinase B-raf
- Serine/threonine-protein kinase RIPK2
- Tyrosine kinase non-receptor protein 2
- Tyrosine-protein kinase BRK
- Vascular endothelial growth factor receptor 2
31 IC50
- CHEMBL2011291
- US9416123, 6
- Cereblon/Histone deacetylase 1
- Cereblon/Histone deacetylase 2
- Cereblon/Histone deacetylase 4
- Cereblon/Histone deacetylase 6
- Histone deacetylase
- Histone deacetylase 1
- Histone deacetylase 1/2
- Histone deacetylase 1/2/3
- Histone deacetylase 10
- Histone deacetylase 11
- Histone deacetylase 2
- Histone deacetylase 3
- Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)
- Histone deacetylase 4
- Histone deacetylase 5
- Histone deacetylase 7
- Histone deacetylase 8
- Histone deacetylase 9
- CHEMBL2018302
- Tubastatin A
- US10227295, Compound Tubastatin A
- US10456394, Tubastatin A
- US8748451, 6
- US9249087, Tubacin
- US9751832, Tubastatin A
- US9956192, Compound Tubastatin-A
- Cyclin-dependent kinase 7
- Death-associated protein kinase 1
- Death-associated protein kinase 2
- Death-associated protein kinase 3
- Dual specificity mitogen-activated protein kinase kinase 4
- Extracellular signal-regulated kinase 5 (ERK5)
- Inhibitor of nuclear factor kappa-B kinase subunit beta
- Interleukin-1 receptor-associated kinase 1
- Mitogen-activated protein kinase 12
- Mitogen-activated protein kinase 13 (MAPK13)
- Mitogen-activated protein kinase 15
- Mitogen-activated protein kinase 8
- Mitogen-activated protein kinase 9
- Myosin light chain kinase family member 4
- Ribosomal protein S6 kinase (P70S6K)
- Serine/threonine-protein kinase 17A
- Serine/threonine-protein kinase DCLK3
- Serine/threonine-protein kinase RIO2
- CHEMBL2152382
- DNA (cytosine-5)-methyltransferase 1 (DNMT1)
- DNA (cytosine-5)-methyltransferase 3B
- DNMT3A2/3L complex
- Histone-arginine methyltransferase CARM1
- Histone-lysine N-methyltransferase EZH2
- Histone-lysine N-methyltransferase MLL2
- Histone-lysine N-methyltransferase MLL3
- Histone-lysine N-methyltransferase MLL4
- Histone-lysine N-methyltransferase SETMAR
- Histone-lysine N-methyltransferase SUV39H1
- Histone-lysine N-methyltransferase SUV39H2 (Suv39H2)
- Histone-lysine N-methyltransferase, H3 lysine-79 specific
- Myeloid/lymphoid or mixed-lineage leukemia (MLL)
- Protein G9a (G9a)
- Protein arginine N-methyltransferase 5
- Protein arginine methyltransferase 3 (PRMT3)
- Protein-arginine N-methyltransferase 1
- SET domain-containing protein 7/9 (Set7/9)
19 IC50
- CHEMBL2204995
- Cyclin-dependent kinase 1
- Cyclooxygenase-1 (COX-1)
- Cytochrome P450 1A
- Cytochrome P450 2C9
- Cytochrome P450 2D6 (2D6)
- Cytochrome P450 3A
- Epidermal growth factor receptor
- Epidermal growth factor receptor and ErbB2 (HER1 and HER2)
- Hepatocyte growth factor receptor
- Insulin-like growth factor I receptor
- MAP kinase p38
- Mast/stem cell growth factor receptor Kit
- Mitogen-activated protein kinase 8
- Mitogen-activated protein kinase 9
- Proto-oncogene tyrosine-protein kinase Src
- RAF proto-oncogene serine/threonine-protein kinase
- Tyrosine-protein kinase ABL1
- Vascular endothelial growth factor receptor 2
19 IC50
- CHEMBL2111784
- 10 kDa chaperonin
- 60 kDa chaperonin
- ATPase (Na+, K+)
- Bile salt export pump
- Cytochrome P450 1A
- Cytochrome P450 2C19
- Cytochrome P450 2C8
- Cytochrome P450 2C9
- Cytochrome P450 2D6 (2D6)
- Cytochrome P450 3A
- HSP60/HSP10
- Multidrug resistance protein 1/Multidrug resistance associated protein 1
- Multidrug resistance-associated protein 2 (MRP2)
- P-glycoprotein 1
- Sarcoplasmic/endoplasmic reticulum calcium ATP-ase
- Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
- Sarcoplasmic/endoplasmic reticulum calcium ATPase 2
- Thiosulfate sulfurtransferase
- ABAMECTIN
- Axin-1/Glycogen synthase kinase-3 beta
- Cyclin-dependent kinase 2
- Epidermal growth factor receptor
- Inhibitor of nuclear factor kappa-B kinase subunit alpha
- Inhibitor of nuclear factor kappa-B kinase subunit beta
- Macrophage colony-stimulating factor 1 receptor (CSF1R)
- Mitogen-activated protein kinase 1
- Mitogen-activated protein kinase 10
- Mitogen-activated protein kinase 14
- Mitogen-activated protein kinase 8
- Mitogen-activated protein kinase 9
- Mitogen-activated protein kinase kinase kinase 11
- Receptor tyrosine-protein kinase erbB-2
- Rho-associated protein kinase 1
- Serine/threonine-protein kinase B-raf
- Serine/threonine-protein kinase PLK1
- Serine/threonine-protein kinase Sgk1
- Tyrosine-protein kinase Lck
19 IC50
- CHEMBL1087421
- Axin-1/Glycogen synthase kinase-3 beta
- Cyclin-dependent kinase 2
- Epidermal growth factor receptor
- Inhibitor of nuclear factor kappa-B kinase subunit alpha
- Inhibitor of nuclear factor kappa-B kinase subunit beta
- Macrophage colony-stimulating factor 1 receptor (CSF1R)
- Mitogen-activated protein kinase 1
- Mitogen-activated protein kinase 10
- Mitogen-activated protein kinase 14
- Mitogen-activated protein kinase 8
- Mitogen-activated protein kinase 9
- Mitogen-activated protein kinase kinase kinase 11
- Receptor tyrosine-protein kinase erbB-2
- Rho-associated protein kinase 1
- Serine/threonine-protein kinase B-raf
- Serine/threonine-protein kinase PLK1
- Serine/threonine-protein kinase Sgk1
- Tyrosine-protein kinase Lck
19 IC50
- CHEMBL1088633
- Dual specificity protein phosphatase (VHR)
- Dual specificity protein phosphatase CDC14A
- Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP
- Hematopoietic protein-tyrosine phosphatase (HEPTP)
- Low molecular weight phosphotyrosine protein phosphatase
- Oligopeptide transporter small intestine isoform
- Oligopeptide transporter, kidney isoform
- Protein phosphatase 5 (PP5)
- Protein-tyrosine phosphatase 1B
- Protein-tyrosine phosphatase 1C
- Protein-tyrosine phosphatase MEG2 (PTP-Meg2)
- Protein-tyrosine phosphatase alpha
- Receptor-type tyrosine-protein phosphatase F (LAR)
- Receptor-type tyrosine-protein phosphatase beta (PTPβ)
- Receptor-type tyrosine-protein phosphatase epsilon (PTPε)
- Receptor-type tyrosine-protein phosphatase gamma
- Receptor-type tyrosine-protein phosphatase mu (PTPμ)
- Tyrosine-protein phosphatase non-receptor type 11
- CEFSULODIN
- Cytochrome P450 3A
- Ephrin type-A receptor 2
- Ephrin type-B receptor 4
- Epidermal growth factor receptor
- Fibroblast growth factor receptor 1
- Insulin receptor
- Insulin-like growth factor I receptor
- Mast/stem cell growth factor receptor Kit
- Mitogen-activated protein kinase kinase kinase kinase 3
- Platelet-derived growth factor receptor alpha
- Platelet-derived growth factor receptor beta
- Potassium voltage-gated channel subfamily H member 2
- Proto-oncogene tyrosine-protein kinase Src
- Ribosomal protein S6 kinase alpha-3
- Tyrosine-protein kinase receptor FLT3
- Vascular endothelial growth factor receptor 1
- Vascular endothelial growth factor receptor 2
- Vascular endothelial growth factor receptor 3
20 IC50
- CHEMBL2086760
- CaM kinase IV
- Casein kinase I isoform delta
- Cytochrome P450 2C9
- Cytochrome P450 2D6 (2D6)
- Hepatocyte growth factor receptor
- Inhibitor of nuclear factor kappa-B kinase subunit beta
- Insulin-like growth factor I receptor
- Interleukin-1 receptor-associated kinase 4
- Mitogen-activated protein kinase 1
- RAC-alpha serine/threonine-protein kinase
- Rho-associated protein kinase 2
- Ribosomal protein S6 kinase alpha-3
- Serine/threonine-protein kinase Chk1/2
- Serine/threonine-protein kinase MST2
- Serine/threonine-protein kinase Nek2
- Serine/threonine-protein kinase PLK3
- Testis-specific serine/threonine-protein kinase 2
- Tyrosine-protein kinase JAK2
- CHEMBL2381116
- Cereblon/Histone deacetylase 1
- Cereblon/Histone deacetylase 2
- Cereblon/Histone deacetylase 4
- Cereblon/Histone deacetylase 6
- Histone deacetylase 1
- Histone deacetylase 10
- Histone deacetylase 11
- Histone deacetylase 2
- Histone deacetylase 3
- Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)
- Histone deacetylase 4
- Histone deacetylase 5
- Histone deacetylase 7
- Histone deacetylase 8
- Histone deacetylase 9
- Leukotriene A4 hydrolase
- NAD-dependent deacetylase sirtuin 1
- Proteasome subunit beta type-1/beta type-5
65 IC50
- RICOLINOSTAT
- US10858323, Compound 2
- US8609678, 2-(diphenylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide [26]
- ATPase family AAA domain-containing protein 2
- Bromodomain adjacent to zinc finger domain protein 2A
- Bromodomain and PHD finger-containing protein 3
- Bromodomain and extra-terminal motif (BET)
- Bromodomain-containing protein 1
- Bromodomain-containing protein 4
- Bromodomain-containing protein 7
- Bromodomain-containing protein 9
- CREB-binding protein
- Cat eye syndrome critical region protein 2
- Histone acetyltransferase KAT2A/KAT2B
- Nucleosome-remodeling factor subunit BPTF
- Peregrin
- Protein polybromo-1
- Transcription activator BRG1
- Transcription initiation factor TFIID subunit 1
- Transcription initiation factor TFIID subunit 1-like
- Transcription intermediary factor 1-alpha
- CHEMBL3133807
- 1,3-beta-glucan synthase component GLS2
- CDK4/Cyclin D3
- CDK6/CycD3
- Cytochrome P450 1A
- Cytochrome P450 2C19
- Cytochrome P450 2C9
- Cytochrome P450 2D6
- Cytochrome P450 2E1
- Cytochrome P450 3A
- Focal adhesion kinase 1/vascular endothelial growth factor receptor 3
- JAK3/JAK1
- Tyrosine-protein kinase JAK1
- Tyrosine-protein kinase JAK2
- Tyrosine-protein kinase JAK3
- Tyrosine-protein kinase Lck
- Tyrosine-protein kinase Lyn
- Tyrosine-protein kinase receptor FLT3
- Vascular endothelial growth factor receptor 1
25 IC50
- CHEMBL4447631
- ALK tyrosine kinase receptor
- CDK6/cyclin D1
- Calmodulin/Proto-oncogene tyrosine-protein kinase Src
- Cereblon/BCR/ABL
- Cyclin-Dependent Kinase 4 (CDK4)
- Cyclin-Dependent Kinase 7 (CDK7)
- Discoidin domain-containing receptor 2
- Fibroblast growth factor receptor 1
- Macrophage colony-stimulating factor 1 receptor (CSF1R)
- Mast/stem cell growth factor receptor Kit
- Platelet-derived growth factor receptor
- Serine/threonine-protein kinase Chk1/2
- Serine/threonine-protein kinase NEK2
- Serine/threonine-protein kinase pim-1
- Tyrosine-protein kinase BTK
- Tyrosine-protein kinase Lck
- Tyrosine-protein kinase receptor FLT3
- Vascular endothelial growth factor receptor 2
- CHEMBL4473820
- ALK tyrosine kinase receptor
- Calmodulin/Proto-oncogene tyrosine-protein kinase Src
- Cereblon/BCR/ABL
- Ephrin type-A receptor 2
- Epidermal growth factor receptor
- Fibroblast growth factor receptor 1
- Fibroblast growth factor receptor 2
- Fibroblast growth factor receptor 3
- Fibroblast growth factor receptor 4
- Hepatocyte growth factor receptor
- Insulin-like growth factor I receptor
- Platelet-derived growth factor receptor
- Platelet-derived growth factor receptor beta
- Receptor protein-tyrosine kinase erbB-4
- Receptor tyrosine-protein kinase erbB-2
- Tyrosine-protein kinase BTK
- Vascular endothelial growth factor receptor 1
- Vascular endothelial growth factor receptor 2
18 IC50
- CHEMBL4475243
- 1,3-beta-glucan synthase component GLS2
- 5-lipoxygenase/FLAP
- Bile salt export pump
- Canalicular multispecific organic anion transporter 1
- Cytochrome P450 1A
- Cytochrome P450 2C19
- Cytochrome P450 2C8
- Cytochrome P450 2C9
- Cytochrome P450 2D6
- Cytochrome P450 3A
- Kv channel-interacting protein 2/Potassium voltage-gated channel subfamily D member 3
- Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
- Sodium channel protein type 5 subunit alpha
- Solute carrier organic anion transporter family member 1B1 (OATP1B1)
- Voltage-gated calcium channel
- Voltage-gated potassium channel
- Voltage-gated potassium channel beta subunit Mink
- Voltage-gated potassium channel subunit Kv7.1/Misshapen-like kinase 1
19 IC50
- CHEMBL4474619
- 1,3-beta-glucan synthase component GLS2
- 5-lipoxygenase/FLAP
- Bile salt export pump
- Canalicular multispecific organic anion transporter 1
- Cytochrome P450 1A
- Cytochrome P450 2C19
- Cytochrome P450 2C8
- Cytochrome P450 2C9
- Cytochrome P450 2D6
- Cytochrome P450 3A
- Kv channel-interacting protein 2/Potassium voltage-gated channel subfamily D member 3
- Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
- Sodium channel protein type 5 subunit alpha
- Solute carrier organic anion transporter family member 1B1 (OATP1B1)
- Voltage-gated calcium channel
- Voltage-gated potassium channel
- Voltage-gated potassium channel beta subunit Mink
- Voltage-gated potassium channel subunit Kv7.1/Misshapen-like kinase 1
19 IC50
- CHEMBL4542281
- ALK tyrosine kinase receptor
- Calmodulin/Proto-oncogene tyrosine-protein kinase Src
- Cereblon/BCR/ABL
- Ephrin type-A receptor 2
- Ephrin type-B receptor 2
- Epidermal growth factor receptor
- Fibroblast growth factor receptor 1
- Hepatocyte growth factor receptor
- Insulin-like growth factor I receptor
- Macrophage-stimulating protein receptor
- Mast/stem cell growth factor receptor Kit
- Platelet-derived growth factor receptor
- Platelet-derived growth factor receptor beta
- Proto-oncogene tyrosine-protein kinase receptor Ret
- Receptor protein-tyrosine kinase erbB-4
- Tyrosine-protein kinase receptor UFO
- Vascular endothelial growth factor receptor 1
- Vascular endothelial growth factor receptor 2
- CHEMBL4068255
- Histone Lysine Demethylase
- Histone lysine demethylase PHF8
- Lysine-specific demethylase 2B
- Lysine-specific demethylase 3A
- Lysine-specific demethylase 3B (KDM3B)
- Lysine-specific demethylase 4A
- Lysine-specific demethylase 4C
- Lysine-specific demethylase 4C (KDM4C)
- Lysine-specific demethylase 5A
- Lysine-specific demethylase 5A (KDM5A)
- Lysine-specific demethylase 5B
- Lysine-specific demethylase 5C
- Lysine-specific demethylase 5C (KDM5C)
- Lysine-specific demethylase 5D (KDM5D)
- Lysine-specific demethylase 6A
- Lysine-specific demethylase 6A (KDM6A)
- Lysine-specific demethylase 6B
- Prolyl 4-hydroxylase
- 3-((6-(4,5-Dihydro-1H-benzo[d]azepin-3(2H)-yl)-2-(pyridin-2-yl)pyrimidin-4-yl)amino)propanoic acid
- 3-{[2-(pyridin-2-yl)-6-(2,3,4,5-tetrahydro-1H-3-benzazepin-3-yl)pyrimidin-4-yl]amino}propanoic acid
- GSK J1
- GSK-J1
- GSKJ1
- ABL
- ABL Mutant (E255K)
- ABL Mutant (F359V)
- ABL Mutant (H396P)
- ABL Mutant (M351T)
- ABL Mutant (Q252H)
- ABL Mutant (T315I)
- ABL Mutant (T315N)
- ABL Mutant (Y253F)
- Epidermal growth factor receptor
- Fibroblast growth factor receptor 1
- Platelet-derived growth factor receptor beta
- Proto-oncogene tyrosine-protein kinase Src
- Tyrosine Kinase c-Kit Mutant (N822K)
- Tyrosine Kinase c-Kit Mutant (V559D)
- Tyrosine Kinase c-Kit Mutant (V559D/T670I)
- Tyrosine- and threonine-specific cdc2-inhibitory kinase
- Tyrosine-protein kinase Lck
- 6-(2,6-dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one
- 6-(2,6-dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one
- PD-180970
- PD180970
- 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 2A
- Adrenergic alpha1B
- Adrenergic receptor
- Adrenergic receptor alpha-2
- Alpha adrenergic receptor 1A and 1B
- Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor
- Alpha-1A adrenergic receptor
- Alpha-1D adrenergic receptor
- Alpha-2A adrenergic receptor
- Alpha-2B adrenergic receptor
- Alpha-2C adrenergic receptor
- Axin-1/Glycogen synthase kinase-3 beta
- Cerebral cortex alpha adrenergic receptor
- D(2) dopamine receptor
- D(3) dopamine receptor
- Hsf1 protein
- Serotonin 2 (5-HT2) receptor
- 2,3-dihydro-1,4-benzodioxin-3-ylmethyl-[2-(2,6-dimethoxyphenoxy)ethyl]amine;hydrochloride
- CHEMBL25554
- MLS000859914
- N-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-2-(2,6-dimethoxyphenoxy)ethanamine;hydrochloride
- SMR000326775
- WB-4101
- WB-4101 hydrochloride
- cid_11957505
- Adrenergic receptor alpha
- Adrenergic receptor beta
- Axin-1/Glycogen synthase kinase-3 beta
- CCKBR
- Cannabinoid receptor 1
- Casein kinase I isoform alpha
- Cyclin B/Cyclin-Dependent Kinase 1 (CDK1)/G2/mitotic-specific cyclin B2/G2/mitotic-specific cyclin B3
- Cyclin-Dependent Kinase 1 (CDK1)
- Cyclin-Dependent Kinase 2 (CDK2)
- Cyclin-Dependent Kinase 5 (CDK5)
- Cyclin-Dependent Kinase 9 (CDK9)
- Cyclin-dependent kinase 1
- Dual specificty protein kinase CLK1
- Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
- Glycogen Synthase Kinase-3, beta
- Glycogen synthase kinase 3
- Opioid receptor
- Serotonin 1 (5-HT1) receptor
24 IC50
- 8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,17}]octadeca-1(11),2,4,6,12(17),13,15-heptaen-9-one
- CHEMBL430574
- NSC 641166
- Paullone
- 5-HT5
- 5-HT5B
- 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 1B
- 5-hydroxytryptamine receptor 1B (5HT1B)
- 5-hydroxytryptamine receptor 1D
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 2B
- 5-hydroxytryptamine receptor 2C
- 5-hydroxytryptamine receptor 6
- HTR1D
- HTR1F
- HTR2B
- HTR6
- Serotonin 1 (5-HT1) receptor
- Serotonin 1B/1D receptor
- Serotonin 2 (5-HT2) receptor
- Serotonin receptor 2a and 2b (5HT2A and 5HT2B)
- 5-Methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indole(RU-24969)
- CAS_108028
- CHEMBL18785
- NSC_108028
- RU 24969
- Bile salt export pump
- Canalicular multispecific organic anion transporter 1
- Canalicular multispecific organic anion transporter 2
- Melatonin receptor 1B
- Mu-type opioid receptor
- Multidrug resistance-associated protein 4
- Opioid receptors; mu & delta
- SSTR1
- SSTR2
- SSTR3
- SSTR4
- SSTR5
- Somatostatin receptor
- Somatostatin receptor type 1
- Somatostatin receptor type 2
- Somatostatin receptor type 3
- Somatostatin receptor type 4
- Somatostatin receptor type 5
- 15-28-Somatostatin-28
- CAS_38916-34-6
- CB6417646
- Somatostatin-14
- AGTR1
- Angiotensin II AT1B
- Angiotensin II AT2
- Angiotensin II receptor
- Angiotensin II receptor (AT-1) type-1
- Angiotensin II type 1a (AT-1a) receptor
- Angiotensin IV
- Angiotensin type II receptor
- Angiotensin-converting enzyme
- Bile salt export pump
- Multidrug and toxin extrusion protein 1
- Neprilysin
- Phosphodiesterase 3
- Phosphodiesterase 4
- Platelet glycoprotein VI
- Solute carrier organic anion transporter family member 1B1 (OATP1B1)
- Solute carrier organic anion transporter family member 1B3 (OATP1B3)
- Type-1A angiotensin II receptor
- CAS_114798-26-4
- Losartan
- NSC_3961
- 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 1B
- 5-hydroxytryptamine receptor 1D
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 2B
- 5-hydroxytryptamine receptor 2C
- 5-hydroxytryptamine receptor 2C (5HT2C)
- Alpha-1A adrenergic receptor
- D(1A) dopamine receptor
- D(2) dopamine receptor
- D(3) dopamine receptor
- Gamma-aminobutyric acid receptor subunit alpha-1
- HTR2C
- HTR4
- Histamine H1 receptor
- Serotonin (5-HT) receptor
- Serotonin receptor 2a and 2b (5HT2A and 5HT2B)
- adrenergic Alpha2
- CAS_3277600
- NSC_3277600
- SB204741
- Bile salt export pump
- Canalicular multispecific organic anion transporter 1
- Canalicular multispecific organic anion transporter 2
- Caspase-1
- Caspase-3
- Caspase-4
- Caspase-5
- Caspase-9
- Cyclooxygenase
- Cyclooxygenase-1 (COX-1)
- Intestinal fatty acid-binding protein (hIFABP)
- Liver fatty acid binding protein (rat L-FABP)
- Multidrug resistance-associated protein 4
- PAK 1/CDC42
- Prostaglandin E synthase/G/H synthase 2
- Prostaglandin-H2 D-isomerase
- Rho GTPase Rac1/CDC42
- Serum albumin
1 ΔG°
- CAS_74103-07-4
- KETOROLAC
- Ketorolac tris salt
- Toradol
- 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 1B
- 5-hydroxytryptamine receptor 1D
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 2B
- 5-hydroxytryptamine receptor 2C
- 5-hydroxytryptamine receptor 3A
- Alpha-1A adrenergic receptor
- Alpha-2A adrenergic receptor
- D(1A) dopamine receptor
- D(1B) dopamine receptor
- D(2) dopamine receptor
- D(3) dopamine receptor
- D(4) dopamine receptor
- HTR1B
- HTR2C
- Muscarinic acetylcholine receptor M1
- Sigma non-opioid intracellular receptor 1
33 Ki
- S33084
- 5-HT3A Serotonin Receptor
- 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 1B
- 5-hydroxytryptamine receptor 1D
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 2B
- 5-hydroxytryptamine receptor 2C
- 5-hydroxytryptamine receptor 5A
- 5-hydroxytryptamine receptor 6
- 5-hydroxytryptamine receptor 7
- Adrenergic alpha1B
- Alpha-1A adrenergic receptor
- Alpha-1D adrenergic receptor
- Alpha-2A adrenergic receptor
- Alpha-2B adrenergic receptor
- Alpha-2C adrenergic receptor
- D(3) dopamine receptor
- HTR4
20 Ki
- S32504
- 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 2A
- Alpha-1A adrenergic receptor
- Alpha-2A adrenergic receptor
- Arachidonate 5-lipoxygenase
- Cyclooxygenase
- Cyclooxygenase-1 (COX-1)
- Cysteinyl leukotriene receptor
- D(1A) dopamine receptor
- D(2) dopamine receptor
- Histamine H1 receptor
- Histamine H2 Receptor
- Leukotriene 2
- Muscarinic acetylcholine receptor M1
- Platelet activating factor receptor
- Prostanoid DP receptor
- Prostanoid TP receptor
- Thromboxane A2 Synthase (P450 TxA2)
19 Ki
- K604
- 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 2A
- Alpha-1A adrenergic receptor
- Alpha-2A adrenergic receptor
- Arachidonate 5-lipoxygenase
- Cyclooxygenase
- Cyclooxygenase-1 (COX-1)
- Cysteinyl leukotriene receptor
- D(1A) dopamine receptor
- D(2) dopamine receptor
- Histamine H1 receptor
- Histamine H2 Receptor
- Leukotriene 2
- Muscarinic acetylcholine receptor M1
- Platelet activating factor receptor
- Prostanoid DP receptor
- Prostanoid TP receptor
- Thromboxane A2 Synthase (P450 TxA2)
19 Ki
- K376
- ADRA1B
- Adrenergic alpha1B
- Adrenergic receptor
- Adrenergic receptor alpha
- Alpha adrenergic receptor (1a and 1d)
- Alpha adrenergic receptor 1A and 1B
- Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor
- Alpha-1A adrenergic receptor
- Alpha-1D adrenergic receptor
- Alpha-2A adrenergic receptor
- Alpha-2B adrenergic receptor
- Alpha-2C adrenergic receptor
- Bile salt export pump
- Canalicular multispecific organic anion transporter 1
- Canalicular multispecific organic anion transporter 2
- HLA class I histocompatibility antigen A-3
- Multidrug resistance-associated protein 4
- Potassium voltage-gated channel subfamily H member 2
- CAS_74191-85-8
- DOXAZOSIN
- Doxazosin
- UK 33,274
- Angiotensin-converting enzyme
- Candidapepsin-2
- Cathepsin D
- Cathepsin E
- Chymotrypsin
- Cysteine protease
- Disintegrin and metalloproteinase domain-containing protein 9 (ADAM9)
- HCV NS3-NS4A Serine Proteinase
- HIV-1 Protease
- Human T-cell leukemia virus type I protease
- Human immunodeficiency virus type 1 protease
- Pepsin A
- Pepsinogen A5
- Plasmepsin 2
- Plasmepsin 4 (PM-IV)
- Plasmepsin I
- Protease
- Renin
- (3S,4S)-3-hydroxy-4-[(2S)-2-[(3S,4S)-3-hydroxy-6-methyl-4-[(2S)-3-methyl-2-[(2S)-3-methyl-2-(3-methylbutanamido)butanamido]butanamido]heptanamido]propanamido]-6-methylheptanoic acid
- CHEMBL296588
- Iva-Val-Val-Sta-Ala-Sta-OH
- N-[(3-Methyl-1-oxobutyl)-L-valyl-L-valyl-4-amino-3-hydroxy-6-methylheptanoyl-L-alanyl]-4-amino-3-hydroxy-6-methylheptanoic acid
- PEPSTATIN
- Pepstatine
- US9115083, Pepstatin