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Compounds Sorted by Binding Targets per Compound

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304   310   315   323   339   369   370   371   372   373   374   375   376   377   378   380   381   383   384   
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429   443   447   515   
Compounds Sorted Alphabetically
Compound Name (alphabetical)
Binding Targets
Enz. Inhib. Data
ITC Data
Alternate Compound Names
  • β-Carbonic anhydrase 2 (CA 2)
  • 5-HT3A Serotonin Receptor
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • Alpha carbonic anhydrase
  • Alpha-1A adrenergic receptor
  • Astrosclerin-3
  • Beta-2 adrenergic receptor
  • Beta-carbonic anhydrase
  • Bile salt export pump
  • Bile salt export pump (BSEP)
  • Carbonate dehydratase
  • Carbonic Anhydrase III
  • Carbonic Anhydrase IV
  • Carbonic anhydrase
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 9
  • Carbonic anhydrase, alpha family
  • Carbonic anhydrases; II & IX
  • Cytochrome P450 2J2
  • D(1A) dopamine receptor
  • D(1B) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • DRD1
  • DRD2
  • Delta carbonic anhydrase
  • Dopamine D1 receptor
  • Dopamine receptor
  • HTR6
  • Histamine H1 receptor
  • Muscarinic acetylcholine receptor M2
  • Serotonin (5-HT) receptor
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
  • Sigma non-opioid intracellular receptor 1
  • adrenergic Alpha2
188 Ki 19 IC50 1 Kd
  • CHEMBL26
  • Compound 7
  • N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide
  • SULPIRIDE,(+)
  • SULPIRIDE,(-)
  • Sulpiride
  • Sulpiride, SLP
  • Sulpiride-R
  • US10172837, Sulpiride
  • 3',5'-cyclic phosphodiesterase
  • Acetylcholinesterase and butyrylcholinesterase (AChE and BChE)
  • Bile salt export pump
  • Calcium channel (Type L)
  • Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A
  • Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Heart phosphodiesterase
  • Homo sapiens phosphodiesterase 2A (PDE2A)
  • Multidrug resistance-associated protein 4
  • Phosphodiesterase 1
  • Phosphodiesterase 11A
  • Phosphodiesterase 11A (PDE11A)
  • Phosphodiesterase 3
  • Phosphodiesterase 3 and 5 (PDE3 and PDE5)
  • Phosphodiesterase 4
  • Phosphodiesterase 4 and 5 (PDE4 and PDE5)
  • Phosphodiesterase 5
  • Phosphodiesterase 5A
  • Phosphodiesterase 6
  • Phosphodiesterase 7
  • Phosphodiesterase 8
  • Phosphodiesterase 9A
  • Phosphodiesterase Type 10 (PDE10A)
  • Phosphodiesterase Type 11 (PDE11A)
  • Phosphodiesterase Type 2 (PDE2A)
  • Phosphodiesterase Type 3 (PDE3B)
  • Phosphodiesterase Type 4 (PDE4B)
  • Phosphodiesterase Type 4 (PDE4D)
  • Phosphodiesterase Type 5 (PDE5A)
  • Phosphodiesterase Type 7 (PDE7B)
  • Phosphodiesterase Type 9 (PDE9A)
  • Potassium voltage-gated channel subfamily H member 2
  • Sodium channel protein type 5 subunit alpha
  • Voltage-gated potassium channel beta subunit Mink/subunit Kv7.1
  • cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4B
  • cGMP-inhibited 3',5'-cyclic phosphodiesterase B
  • cGMP-specific 3',5'-cyclic phosphodiesterase
4 Ki 88 IC50 1 EC50
  • (2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,16}]heptadeca-1(10),11(16),12,14-tetraene-4,7-dione
  • (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2-methyl-2,3,6,7,12,12a-hexahydropyrazino[1,2,1,6]pyrido[3,4-b]indole-1,4-dione
  • CHEMBL779
  • Cialis
  • GF 196960
  • Tadalafil
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • Acetylcholine receptor protein alpha chain/beta chain/delta chain /gamma chain
  • Alpha-1A adrenergic receptor
  • Alpha-2A adrenergic receptor
  • Beta-1 adrenergic receptor
  • Beta-2 adrenergic receptor
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • Gamma-aminobutyric acid receptor subunit alpha-1
  • Histamine H1 receptor
  • Monoamine transporter
  • Multidrug resistance-associated protein 4
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • Muscarinic acetylcholine receptor M4
  • Muscarinic acetylcholine receptor M5
  • Neuronal acetylcholine receptor Alpha-4/Beta-2
  • Neuronal acetylcholine receptor protein alpha-3/beta-2 subunit
  • Neuronal acetylcholine receptor protein alpha-4/beta-4 subunit
  • Neuronal acetylcholine receptor protein alpha-7 subunit
  • Neuronal acetylcholine receptor; alpha3/beta4
  • Norepinephrine transporter
  • Potassium voltage-gated channel subfamily H member 2
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
  • Sodium-dependent dopamine transporter
  • Sodium-dependent noradrenaline transporter
  • Sodium-dependent serotonin transporter
  • Uridine-5'-diphosphoglucuronosyltransferase 1A1
  • Uridine-5'-diphosphoglucuronosyltransferase 1A4
  • Uridine-5'-diphosphoglucuronosyltransferase 1A6
  • Uridine-5'-diphosphoglucuronosyltransferase 2B10
  • Uridine-5'-diphosphoglucuronosyltransferase 2B7
  • adrenergic Alpha2
  • n-AChR
66 Ki 45 IC50
  • 2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one
  • BUPROPION
  • BUPROPION HYDROCHLORIDE
  • CHEMBL894
  • US9944618, Compound ID No. 176
  • 3-phosphoinositide dependent protein kinase-1
  • ALK tyrosine kinase receptor
  • Aurora kinase A/Targeting protein for Xklp2
  • Axin-1/Glycogen synthase kinase-3 beta
  • Cyclin-Dependent Kinase 4 (CDK4)
  • Cyclin-dependent kinase 2
  • Ephrin receptor
  • Ephrin type-B receptor 4
  • Epidermal growth factor receptor
  • Fibroblast growth factor receptor 3
  • Fibroblast growth factor receptor 4
  • Hepatocyte growth factor receptor
  • Insulin receptor
  • Insulin-like growth factor I receptor
  • MAP kinase-activated protein kinase 2
  • MAP kinase-interacting serine/threonine-protein kinase 2
  • Mast/stem cell growth factor receptor Kit
  • Mitogen-activated protein kinase 1
  • Mitogen-activated protein kinase 14
  • Mitogen-activated protein kinase kinase kinase 8
  • Non-receptor tyrosine-protein kinase TYK2
  • Platelet-derived growth factor receptor alpha
  • Protein kinase C alpha type
  • Protein kinase C theta type
  • Protein kinase N1
  • Protein kinase N2
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Receptor tyrosine-protein kinase erbB-2
  • Rho-associated protein kinase 2
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase BTK
  • Tyrosine-protein kinase JAK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase JAK3
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase SYK
  • Tyrosine-protein kinase ZAP-70
  • Tyrosine-protein kinase receptor UFO
  • Vascular endothelial growth factor receptor 2
  • cAMP-dependent protein kinase (PKA)
44 IC50
  • CHEMBL3786167
  • 3-phosphoinositide dependent protein kinase-1
  • ALK tyrosine kinase receptor
  • Aurora kinase A/Targeting protein for Xklp2
  • Axin-1/Glycogen synthase kinase-3 beta
  • Cyclin-Dependent Kinase 4 (CDK4)
  • Cyclin-dependent kinase 2
  • Ephrin receptor
  • Ephrin type-B receptor 4
  • Epidermal growth factor receptor
  • Fibroblast growth factor receptor 3
  • Fibroblast growth factor receptor 4
  • Hepatocyte growth factor receptor
  • Insulin receptor
  • Insulin-like growth factor I receptor
  • MAP kinase-activated protein kinase 2
  • MAP kinase-activated protein kinase 5
  • MAP kinase-interacting serine/threonine-protein kinase 2
  • Mast/stem cell growth factor receptor Kit
  • Mitogen-activated protein kinase 1
  • Mitogen-activated protein kinase 14
  • Mitogen-activated protein kinase kinase kinase 8
  • Non-receptor tyrosine-protein kinase TYK2
  • Platelet-derived growth factor receptor alpha
  • Potassium voltage-gated channel subfamily H member 2
  • Protein kinase C alpha type
  • Protein kinase C theta type
  • Protein kinase N1
  • Protein kinase N2
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Receptor tyrosine-protein kinase erbB-2
  • Rho-associated protein kinase 2
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase BTK
  • Tyrosine-protein kinase JAK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase JAK3
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase SYK
  • Vascular endothelial growth factor receptor 2
  • cAMP-dependent protein kinase (PKA)
44 IC50
  • CHEMBL3785500
  • ALK tyrosine kinase receptor
  • Axin-1/Glycogen synthase kinase-3 beta
  • COUP transcription factor 1
  • Cyclin-dependent kinase 2
  • Epidermal growth factor receptor
  • Epidermal growth factor receptor(L858R)
  • Epidermal growth factor receptor(L858R, T790M)
  • Hepatocyte growth factor receptor
  • Insulin receptor
  • Insulin-like growth factor I receptor
  • Interleukin-1 receptor-associated kinase 4
  • Lysyl-tRNA synthetase
  • MAP kinase-activated protein kinase 2
  • MAP kinase-activated protein kinase 5
  • MAP kinase-interacting serine/threonine-protein kinase 1
  • MAP kinase-interacting serine/threonine-protein kinase 2
  • Macrophage-stimulating protein receptor
  • Mast/stem cell growth factor receptor Kit
  • Mitogen-activated protein kinase 1
  • Mitogen-activated protein kinase 12
  • Mitogen-activated protein kinase 14
  • Mitogen-activated protein kinase 9
  • Non-receptor tyrosine-protein kinase TYK2
  • Protein kinase C alpha type
  • Protein kinase C theta type
  • Protein kinase N1
  • Protein kinase N2
  • Proto-oncogene tyrosine-protein kinase Src
  • RAC-alpha serine/threonine-protein kinase
  • Receptor protein-tyrosine kinase erbB-4
  • Receptor tyrosine-protein kinase erbB-2
  • Rho-associated protein kinase 2
  • Serine/threonine-protein kinase PLK1
  • Serine/threonine-protein kinase WNK1
  • Serine/threonine-protein kinase pim-2
  • Tyrosine-protein kinase JAK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase JAK3
  • Vascular endothelial growth factor receptor 2
  • [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial
45 IC50 1 Kd
  • CHEMBL2178352
  • US9096601, 8-26