BDBM50240843 2-Aminothiazole::Aminothiazole::Aminothiazoline::Basedol::CHEMBL344760::Thiazol-2-ylamine::thiazol-2-amine

SMILES Nc1nccs1

InChI Key InChIKey=RAIPHJJURHTUIC-UHFFFAOYSA-N

Data  1 KI  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50240843   

TargetNitric oxide synthase, brain(Homo sapiens (Human))
Instituto De QuíMica MéDica

Curated by ChEMBL
LigandPNGBDBM50240843(2-Aminothiazole | Aminothiazole | Aminothiazoline ...)
Affinity DataKi:  1.20E+4nMAssay Description:Inhibition of nNOS (unknown origin) assessed as conversion of L-[3H]arginine to L-[3H]citrullineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50240843(2-Aminothiazole | Aminothiazole | Aminothiazoline ...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of inducible nitric oxide synthetase in LPS-stimulated mouse ANA1 macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50240843(2-Aminothiazole | Aminothiazole | Aminothiazoline ...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of iNOS in mouse ANA1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed