BDBM29609 4-alpha-Cumylphenol::4-cumylphenol::US9688816, B

SMILES CC(C)(c1ccccc1)c1ccc(O)cc1

InChI Key InChIKey=QBDSZLJBMIMQRS-UHFFFAOYSA-N

Data  6 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 29609   

TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Kyushu University

LigandPNGBDBM29609(4-alpha-Cumylphenol | 4-cumylphenol | US9688816, B)
Affinity DataIC50:  13.9nMpH: 7.4 T: 2°CAssay Description:The receptor-binding assay was conducted using [3H]4-hydroxytamoxifen (4-OHT) as the radioligand. To estimate the binding affinity, the IC50 values (...More data for this Ligand-Target Pair
TargetAndrogen receptor(Rattus norvegicus (Rat))
University Of Basel

Curated by ChEMBL
LigandPNGBDBM29609(4-alpha-Cumylphenol | 4-cumylphenol | US9688816, B)
Affinity DataIC50:  3.98E+4nMAssay Description:Inhibitory concentration against recombinant rat androgen receptor expressed in Escherichia coli using [3H]methyltrienolone (R 1881)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Sabic Global Technologies

US Patent
LigandPNGBDBM29609(4-alpha-Cumylphenol | 4-cumylphenol | US9688816, B)
Affinity DataIC50:  1.40E+5nMAssay Description:Competitive binding assays were performed by incubating rhER alpha (α) and beta 1 (β1) receptors with 10 nM [3H]estradiol (the radio ligand...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEstrogen receptor beta(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM29609(4-alpha-Cumylphenol | 4-cumylphenol | US9688816, B)
Affinity DataIC50:  1.30E+4nMAssay Description:Antagonist activity at human Gal4-fused ERbeta expressed in HEK293 cells assessed as inhibition of E2-induced transcriptional activation after 24 hrs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Sabic Global Technologies

US Patent
LigandPNGBDBM29609(4-alpha-Cumylphenol | 4-cumylphenol | US9688816, B)
Affinity DataEC50:  4.40E+3nMAssay Description:Agonist activity at human Gal4-fused ERalpha expressed in HEK293 cells assessed as transcriptional activation after 24 hrs by luciferase/beta-galacto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Sabic Global Technologies

US Patent
LigandPNGBDBM29609(4-alpha-Cumylphenol | 4-cumylphenol | US9688816, B)
Affinity DataIC50:  2.40E+4nMAssay Description:Antagonist activity at human Gal4-fused ERalpha expressed in HEK293 cells assessed as inhibition of E2-induced transcriptional activation after 24 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM29609(4-alpha-Cumylphenol | 4-cumylphenol | US9688816, B)
Affinity DataIC50:  9.80E+3nMAssay Description:Competitive binding assays were performed by incubating rhER alpha (α) and beta 1 (β1) receptors with 10 nM [3H]estradiol (the radio ligand...More data for this Ligand-Target Pair
In DepthDetails US Patent