BDBM50240945 (E)-1-(5-hydroxy-2,2-dimethyl-2H-chromen-6-yl)-3-(4-hydroxyphenyl)prop-2-en-1-one::1-(5-Hydroxy-2,2-dimethyl-2H-chromen-6-yl)-3-(4-hydroxy-phenyl)-propenone::4-hydroxyisolonchocarpin::4-hydroxylonchocarpin::CHEMBL362378
SMILES CC1(C)Oc2ccc(C(=O)\C=C\c3ccc(O)cc3)c(O)c2C=C1
InChI Key InChIKey=IQHPDUUSMBMDGN-WEVVVXLNSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50240945
Affinity DataKi: 3.48E+3nMAssay Description:Mixed type inhibition of BChE (unknown origin) using butyrylthiocholine iodide as substrate by Ellman's method based Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 7.39E+3nMAssay Description:Competitive type inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate by Ellman's method based Lineweaver-Burk plot analys...More data for this Ligand-Target Pair
Affinity DataIC50: 1.71E+4nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate by spectrophotometry based Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.57E+3nMAssay Description:Binding affinity to BChE (unknown origin) assessed as reduction in intrinsic protein fluorescence at 25 degC by fluorescence spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.96E+4nMAssay Description:Binding affinity to AChE (unknown origin) assessed as reduction in intrinsic protein fluorescence at 25 degC by fluorescence spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 5.68E+3nMAssay Description:Inhibition of BChE (unknown origin) using butyrylthiocholine iodide as substrate by spectrophotometry based Ellman's methodMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Toho University
Curated by ChEMBL
Toho University
Curated by ChEMBL
Affinity DataIC50: 7.41E+4nMAssay Description:Inhibition of PTP1B (unknown origin) using p-nitrophenyl phosphate as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of phorbol ester-induced ornithine decraboxylase in human MCF7 cells after 6 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in baculovirus-expression system using Rh-EVNLDAEFK-Quencher substrate by FRET assayMore data for this Ligand-Target Pair