BDBM22880 2-(5-methyl-1H-imidazol-4-yl)ethan-1-amine::4-Methylhistamine::Methylhistamine-4
SMILES Cc1nc[nH]c1CCN
InChI Key InChIKey=UGYXPZQILZRKJJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 22880
Affinity DataKi: 50nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor expressed in Sf9 cells coexpressing RGS19, Galphai2, Gbeta1gamma2More data for this Ligand-Target Pair
Affinity DataKi: 50nM ΔG°: -10.4kcal/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on The SK-N-MC/hH4R cell homogenates. Retained radioactivity was determined by liquid scintillation countin...More data for this Ligand-Target Pair
Affinity DataKi: 6.31E+3nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7.94E+3nMAssay Description:Displacement of [125I]iodoaminopotentidine from human histamine H2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetHistamine H2 receptor(Cavia porcellus (domestic guinea pig))
Hoechst Pharmaceutical Research Laboratories
Curated by PDSP Ki Database
Hoechst Pharmaceutical Research Laboratories
Curated by PDSP Ki Database
Affinity DataEC50: 1.59E+3nMAssay Description:Agonist activity at mouse histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 32nMAssay Description:Agonist activity at human recombinant histamine H4 receptor expressed in Sf9 cells coexpressing RGS19, Galphai2, Gbeta1gamma2 by steady-state GTPase ...More data for this Ligand-Target Pair
Affinity DataEC50: 3.16E+3nMAssay Description:Agonist activity at human histamine H2 receptor expressed in Sf9 cells coexpressing Gsalphas by steady-state GTPase activity assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.51E+3nMAssay Description:Agonist activity at rat histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 70.8nMAssay Description:Agonist activity at human histamine H4 receptor expressed in Sf9 cells coexpressing RGS19 protein by steady-state GTPase assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.88E+3nMAssay Description:Agonist activity at human histamine H2 receptor expressed in Sf9 cells coexpressing GsalphaS protein by steady-state GTPase assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.58E+4nMAssay Description:Agonist activity at human histamine H1 receptor expressed in Sf9 cells coexpressing RGS4 by steady-state GTPase assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.24E+4nMAssay Description:Agonist activity at human histamine H3 receptor expressed in sf9 cell membrane co-expressing mammalian Galphai2 and Gbeta1gamma2 incubated for 90 min...More data for this Ligand-Target Pair
Affinity DataEC50: 40nMAssay Description:Agonist activity at human histamine H4 receptor expressed in human SK-N-MC cells by CRE-beta galactosidase reporter gene assayMore data for this Ligand-Target Pair