BDBM50124157 4-nitrophenylsulfamide::CHEMBL168778::N-(4-nitrophenyl)sulfamide

SMILES NS(=O)(=O)Nc1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=RAXPQAODVUNKFW-UHFFFAOYSA-N

Data  4 KI  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50124157   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50124157(4-nitrophenylsulfamide | CHEMBL168778 | N-(4-nitro...)
Affinity DataKi:  13nMAssay Description:Inhibitory activity against human cloned isoenzyme carbonic anhydrase II (hCA II), by esterase method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50124157(4-nitrophenylsulfamide | CHEMBL168778 | N-(4-nitro...)
Affinity DataKi:  18nMAssay Description:Inhibitory activity against human cloned isoenzyme carbonic anhydrase I (hCA I), by esterase method.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50124157(4-nitrophenylsulfamide | CHEMBL168778 | N-(4-nitro...)
Affinity DataKi:  892nMAssay Description:Inhibition of human CA2 by carbon dioxide hydrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50124157(4-nitrophenylsulfamide | CHEMBL168778 | N-(4-nitro...)
Affinity DataKi:  1.74E+3nMAssay Description:Inhibition of human CA2 by 4-nitrophenyl acetate hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50124157(4-nitrophenylsulfamide | CHEMBL168778 | N-(4-nitro...)
Affinity DataKd:  1.00E+3nMpH: 7.5Assay Description:Binding affinity to human CA2 in presence of sodium sulfate and ANS at pH 7.5 by ThermoFluor assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50124157(4-nitrophenylsulfamide | CHEMBL168778 | N-(4-nitro...)
Affinity DataKd:  1.50E+3nMpH: 7.4Assay Description:Binding affinity to human CA2 at pH 7.4 by ThermoFluor assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed