BDBM16649 2,2-dimethyl-N-(4-sulfamoylphenyl)propanamide::4-Pivaloylamido-benzenesulfonamide::CHEMBL23285::aromatic sulfonamide compound 14
SMILES CC(C)(C)C(=O)Nc1ccc(cc1)S(N)(=O)=O
InChI Key InChIKey=KGBTVIQRHXYTRQ-UHFFFAOYSA-N
Data 12 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 16649
Affinity DataKi: 96nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 136nMAssay Description:Inhibitiory activity against human Carbonic anhydrase IX (hCA IX)More data for this Ligand-Target Pair
Affinity DataKi: 230nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
Affinity DataKi: 230nMAssay Description:Inhibitiory activity against human Carbonic anhydrase II (hCA II)More data for this Ligand-Target Pair
Affinity DataKi: 249nMAssay Description:Inhibitiory activity against human Carbonic anhydrase XII (hCA XII)More data for this Ligand-Target Pair
TargetCarbonic anhydrase 14(Homo sapiens (Human))
The Hebrew University Of Jerusalem
Curated by ChEMBL
The Hebrew University Of Jerusalem
Curated by ChEMBL
Affinity DataKi: 730nMAssay Description:Inhibition of human carbonic anhydrase 14 preincubated with compound for 15 mins by carbon dioxide hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.50E+3nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated with compound for 15 mins by carbon dioxide hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.55E+3nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
Affinity DataKi: 5.90E+3nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated with compound for 15 mins by carbon dioxide hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.20E+3nMAssay Description:Inhibition of human carbonic anhydrase 7 preincubated with compound for 15 mins by carbon dioxide hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.06E+4nM ΔG°: -6.39kcal/molepH: 7.4 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
Affinity DataKi: 2.06E+4nMAssay Description:Inhibitiory activity against human Carbonic anhydrase I (hCA I)More data for this Ligand-Target Pair