BDBM50304144 5-NITROINDAZOLE::5-Nitro-1H-indazole::CHEMBL165372

SMILES [O-][N+](=O)c1ccc2[nH]ncc2c1

InChI Key InChIKey=WSGURAYTCUVDQL-UHFFFAOYSA-N

Data  2 KI  2 IC50

PDB links: 3 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50304144   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50304144(5-NITROINDAZOLE | 5-Nitro-1H-indazole | CHEMBL1653...)
Affinity DataKi:  5.60E+5nMAssay Description:Inhibition of human N-terminal His6-tagged PDE10A2 catalytic domain expressed in Escherichia coli BL21(DE3) RIL cells using 3',5'-cGMP as substrate b...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50304144(5-NITROINDAZOLE | 5-Nitro-1H-indazole | CHEMBL1653...)
Affinity DataKi:  5.60E+5nMAssay Description:Inhibition of human N-terminal His6-tagged PDE10A2 catalytic domain expressed in Escherichia coli BL21(DE3) RIL cells using 3',5'-cGMP as substrate b...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50304144(5-NITROINDAZOLE | 5-Nitro-1H-indazole | CHEMBL1653...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus-infected insect cells using p-tyraimne substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Uned

Curated by ChEMBL
LigandPNGBDBM50304144(5-NITROINDAZOLE | 5-Nitro-1H-indazole | CHEMBL1653...)
Affinity DataIC50:  4.70E+4nMAssay Description:Inhibition of NOS1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed