BDBM50187658 4',5-dihydroxy-7-methoxy flavone::4',5-dihydroxy-7-methoxyflavone::5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-chromen-4-one::7-O-methylapigenin::CHEMBL210635::Gonkwanin::genkwanin
SMILES COc1cc(O)c2c(c1)oc(cc2=O)-c1ccc(O)cc1
InChI Key InChIKey=JPMYFOBNRRGFNO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50187658
Affinity DataKi: >2.34E+3nMAssay Description:Inhibition of CYP1B1 EROD activity assessed as inhibition of deethylation of 7-ethoxyresorufin to resorufinMore data for this Ligand-Target Pair
Affinity DataKi: >2.34E+3nMAssay Description:Inhibition of CYP1A1 EROD activity assessed as inhibition of deethylation of 7-ethoxyresorufin to resorufinMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
The Chinese University Of Hong Kong (Shenzhen)
Curated by ChEMBL
The Chinese University Of Hong Kong (Shenzhen)
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of recombinant His-tagged human FLT3 (564 to 958 residues) expressed in baculovirus expression system using tyr 02 as substrate incubated ...More data for this Ligand-Target Pair
TargetInositol polyphosphate multikinase(Homo sapiens)
National Institute Of Environmental Health Sciences
Curated by ChEMBL
National Institute Of Environmental Health Sciences
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human IPMK using insP3 as substrate preincubated for 15 mins followed by substrate and measured after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetInositol hexakisphosphate kinase 2(Homo sapiens)
National Institute Of Environmental Health Sciences
Curated by ChEMBL
National Institute Of Environmental Health Sciences
Curated by ChEMBL
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of human IP6K2 using insP6 as substrate preincubated for 15 mins followed by substrate and measured after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
The Chinese University Of Hong Kong (Shenzhen)
Curated by ChEMBL
The Chinese University Of Hong Kong (Shenzhen)
Curated by ChEMBL
Affinity DataIC50: 979nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human full length MNK2 expressed in baculovirus expression system incubated for 1 hr by Kinase Tracer...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human Neu2 assessed as MuNANA substrate hydrolysis in presence of 0.1% Triton X-100 by discontinuous fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.81E+5nMAssay Description:Inhibition of p56 lckMore data for this Ligand-Target Pair
Affinity DataIC50: >7.03E+5nMAssay Description:Inhibition of HIV1 RTMore data for this Ligand-Target Pair