BDBM50240783 1,2,4-Trimethoxy-5-propenyl-benzene::17-(1,5-Dimethyl-hexyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol; compound with 1,2,4-trimethoxy-5-propenyl-benzene (Alphaasarone and cholesterol)::CHEMBL333306::alpha-Asarone::trans-asarone

SMILES COc1cc(OC)c(\C=C\C)cc1OC

InChI Key InChIKey=RKFAZBXYICVSKP-AATRIKPKSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50240783   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Instituto Polit£Cnico Nacional (Ipn)

Curated by ChEMBL
LigandPNGBDBM50240783(1,2,4-Trimethoxy-5-propenyl-benzene | 17-(1,5-Dime...)
Affinity DataIC50:  5.86E+3nMAssay Description:Inhibition of human HMG-CoA reductase activity using NADPH by spectrophotometricallyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Toyama Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50240783(1,2,4-Trimethoxy-5-propenyl-benzene | 17-(1,5-Dime...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human liver microsome CYP2D6 in assessed as [14C]formaldehyde formationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Schizosaccharomyces pombe)
Instituto Polit£Cnico Nacional (Ipn)

Curated by ChEMBL
LigandPNGBDBM50240783(1,2,4-Trimethoxy-5-propenyl-benzene | 17-(1,5-Dime...)
Affinity DataIC50:  2.49E+6nMAssay Description:Inhibition of Schizosaccharomyces pombe HMG-CoA reductase by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Instituto Polit£Cnico Nacional (Ipn)

Curated by ChEMBL
LigandPNGBDBM50240783(1,2,4-Trimethoxy-5-propenyl-benzene | 17-(1,5-Dime...)
Affinity DataIC50:  36nMAssay Description:Inhibition of human HMG-CoA reductase after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed