BDBM8592 (2R,15S)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-ene-5,14-dione::4-Androsten-3,17-dione::Androst-4-ene-3,17-dione::Androstenedione::[1beta-3H] androstenedione

SMILES C[C@]12CCC3C(CCC4=CC(=O)CC[C@]34C)C1CCC2=O

InChI Key InChIKey=AEMFNILZOJDQLW-WFZCBACDSA-N

Data  1 KI  1 IC50

PDB links: 7 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 8592   

TargetAromatase(Homo sapiens (Human))
Tohoku College Of Pharmacy

LigandPNGBDBM8592((2R,15S)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{...)
Affinity DataKi:  20nM ΔG°:  -10.9kcal/mole IC50:  300nMpH: 7.5 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1beta-3H] Androstenedione during aromatization. After incubation, the re...More data for this Ligand-Target Pair