BDBM50292627 (RS)-9-chloro-6-(2-chlorophenyl)-4-hydroxy-2,5-diazabicyclo[5.4.0]undeca-5,8,10,12-tetraen-3-one::7-Chloro-5-(2-chloro-phenyl)-3-hydroxy-1,3-dihydro-benzo[e][1,4]diazepin-2-one::7-Chloro-5-(2-chloro-phenyl)-3-hydroxy-1,3-dihydro-benzo[e][1,4]diazepin-2-one (lorazepam)::7-chloro-5-(2-chlorophenyl)-3-hydroxy-1H-benzo[e][1,4]diazepin-2(3H)-one::Ativan::CHEMBL580::LORAZEPAM::LORAZEPAM7-Chloro-5-(2-chloro-phenyl)-3-hydroxy-1,3-dihydro-benzo[e][1,4]diazepin-2-one::Loraz::Lorazepam intensol::Lorazepam preservative free::WY-4036

SMILES OC1N=C(c2ccccc2Cl)c2cc(Cl)ccc2NC1=O

InChI Key InChIKey=DIWRORZWFLOCLC-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50292627   

TargetFatty acid-binding protein, liver(Rattus norvegicus (Rat))
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50292627((RS)-9-chloro-6-(2-chlorophenyl)-4-hydroxy-2,5-dia...)
Affinity DataKi:  1.29E+4nMAssay Description:Displacement of 1-anilinonaphthalene-8-sulphonic acid from rat recombinant L-FABP high binding affinity site expressed in Escherichia coli BL21 by co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein, liver(Rattus norvegicus (Rat))
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50292627((RS)-9-chloro-6-(2-chlorophenyl)-4-hydroxy-2,5-dia...)
Affinity DataKi:  1.40E+5nMAssay Description:Displacement of 1-anilinonaphthalene-8-sulphonic acid from rat recombinant L-FABP low binding affinity site expressed in Escherichia coli BL21 by com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Homo sapiens (Human))
Harvard University

Curated by ChEMBL
LigandPNGBDBM50292627((RS)-9-chloro-6-(2-chlorophenyl)-4-hydroxy-2,5-dia...)
Affinity DataIC50:  2.85E+8nMAssay Description:Binding affinity of compound towards Benzodiazepine receptor in a competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank