BDBM50431275 CARMOFUR::Carm-ofur::Mifurol::med.21724, Compound 152
SMILES CCCCCCNC(=O)n1cc(F)c(=O)[nH]c1=O
InChI Key InChIKey=AOCCBINRVIKJHY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50431275
TargetAcid ceramidase(Rattus norvegicus (Rat))
Fondazione Istituto Italiano Di Tecnologia
Curated by ChEMBL
Fondazione Istituto Italiano Di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of human C-terminal His-tagged acid ceramidase variant 1 expressed in HEK293 cells using fluorogenic substrate Rbm-14-12 preincubated for ...More data for this Ligand-Target Pair
Affinity DataIC50: 191nMAssay Description:Inhibition of acid ceramidase in human A375 cells using fluorogenic substrate Rbm-14-12 preincubated for 2 hrs followed by substrate addition measure...More data for this Ligand-Target Pair
Affinity DataIC50: 759nMAssay Description:Inhibition of acid ceramidase in human G361 cells using fluorogenic substrate Rbm-14-12 preincubated for 2 hrs followed by substrate addition measure...More data for this Ligand-Target Pair
Affinity DataIC50: 1.82E+3nMAssay Description:This is a review article.More data for this Ligand-Target Pair
Affinity DataIC50: 1.82E+3nMAssay Description:Recombinant SARS-CoV-2 Mpro with native N and C termini was expressed in Escherichia coli, and subsequently purified (Extended Data Fig. 1a, b). The ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibition of SARS-CoV-2 MProMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
Affinity DataEC50: 2.43E+4nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
Affinity DataIC50: 1.82E+3nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Assam University (A Central University)
Curated by ChEMBL
Assam University (A Central University)
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of rat FAAH using [3H]-AEA as substrate by liquid chromatography-mass spectrometryMore data for this Ligand-Target Pair
TargetAcid ceramidase(Rattus norvegicus (Rat))
Fondazione Istituto Italiano Di Tecnologia
Curated by ChEMBL
Fondazione Istituto Italiano Di Tecnologia
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of rat acid ceramidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibition of SARS-CoV-2 MPro expressed in Escherichia coli BL21 (DE3) using Mca-AVLQ SGFR-K(Dnp)K as substrate by EnVision multimode plate reader an...More data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair