BDBM13373 (2S)-2-[(2S)-2-[(2S)-2-[(2R)-2-amino-3-sulfanylpropanamido]-3-methylbutanamido]-3-phenylpropanamido]-4-(methylsulfanyl)butanoic acid::CHEMBL289302::CHEMBL553980::CVFM
SMILES CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@@H](N)CS)C(C)C)C(O)=O
InChI Key InChIKey=PCFMKLVXKKAJSV-XSLAGTTESA-N
Data 11 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 13373
TargetProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Universita Di Napoli Federico Ii
Universita Di Napoli Federico Ii
Affinity DataIC50: 600nMpH: 7.5 T: 2°CAssay Description:Assays for PFT activity were performed with a PFT-specific scintillation assay (SPA) kit (Amersham Biosciences, Piscataway, NJ). IC50 values were cal...More data for this Ligand-Target Pair
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Centre De Recherches De Vitry-Alfortville
Curated by ChEMBL
Centre De Recherches De Vitry-Alfortville
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of [3H]-FPP incorporation into human Ha-Ras by farnesyltransferaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of Human farnesyl transferaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Rattus norvegicus)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:In vitro inhibitory concentration evaluated against P21ras Farnesyl transferaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Rattus norvegicus)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of farnesyl transferase (FTase) of rat brainMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant FTase using [3H]farnesyldiphosphateMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:In vitro inhibition of bovine Farnesyltrasferase.More data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:In vitro inhibiion of bovine farnesyl transferaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of farnesyl transferase in NIH3T3 cell based assay in non-reducing (-DTT) conditionsMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Rattus norvegicus)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Department Of Chemistry And School Of Molecular Science(Bk21)
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of bovine FarnesyltransferaseMore data for this Ligand-Target Pair