BDBM50428474 DITIOCARB::Diethyldithiocarbamate

SMILES CCN(CC)C(S)=S

InChI Key InChIKey=LMBWSYZSUOEYSN-UHFFFAOYSA-N

Data  3 KI  1 IC50

PDB links: 3 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50428474   

TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50428474(DITIOCARB | Diethyldithiocarbamate)
Affinity DataKi:  7.90E+5nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Istituto Di Biochimica Delle Proteine (Ibp)

Curated by ChEMBL
LigandPNGBDBM50428474(DITIOCARB | Diethyldithiocarbamate)
Affinity DataKi:  3.10E+6nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Istituto Di Biochimica Delle Proteine (Ibp)

Curated by ChEMBL
LigandPNGBDBM50428474(DITIOCARB | Diethyldithiocarbamate)
Affinity DataKi:  3.10E+6nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt export pump(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50428474(DITIOCARB | Diethyldithiocarbamate)
Affinity DataIC50:  6.93E+4nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed