BDBM50000663 (+)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]hexadeca-2(7),3,5,10(15),11,13-hexaene::(+)-MK-801::(+)MK-801::(+/-) MK-8011-methyl-(9R,1R)-16-azatetracyclo[7.6.1.02,7.010,15]hexadeca-2(7),3,5,10(15),11,13-hexaene::(+/-)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]hexadeca-2(7),3,5,10(15),11,13-hexaene::(+/-)-MK801::(-)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]hexadeca-2(7),3,5,10(15),11,13-hexaene::(-)-MK801::(1S,9R)-1-methyl-16-azatetracyclo[7.6.1.0^{2,7}.0^{10,15}]hexadeca-2(7),3,5,10(15),11,13-hexaene::(1S,9R)-1-methyl-16-azatetracyclo[7.6.1.0^{2,7}.0^{10,15}]hexadeca-2,4,6,10(15),11,13-hexaene::(5S,10R)-(+)-5-methyl-10,11-dihydro-5Hdibenzo[a,d]cyclohepten-5,10-imine::(5S,10S)-(+)-5-methyl-10,11-dihydro-5Hdibenzo[a,d]cyclohepten-5,10-imine::(Dizocilpine)1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]hexadeca-2(7),3,5,10(15),11,13-hexaene::(MK-801)1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]hexadeca-2(7),3,5,10(15),11,13-hexaene::1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]hexadeca-2(7),3,5,10(15),11,13-hexaene::1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]hexadeca-2(7),3,5,10(15),11,13-hexaene(MK-801)::1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]hexadeca-2(7),3,5,10,12,14-hexaene::1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]hexadeca-2,4,6,10(15),11,13-hexaene::10,11-Dihydro-5-methyl-5H-dibenzo[a,d]cyclohepten-5,10-imine.(MK-801)::CHEMBL284237::MK-801::MK-801 (Dizocilpine)::MK-801,(+)::MK-801,(-)::dizocilpine

SMILES C[C@]12NC(Cc3ccccc13)c1ccccc21

InChI Key InChIKey=LBOJYSIDWZQNJS-LYKKTTPLSA-N

Data  16 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50000663   

LigandPNGBDBM50000663((+)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]he...)
Affinity DataKi:  2.5nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50000663((+)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]he...)
Affinity DataKi:  6.5nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50000663((+)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]he...)
Affinity DataKi:  8.40nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50000663((+)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]he...)
Affinity DataKi:  8.90nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50000663((+)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]he...)
Affinity DataKi:  9.40nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50000663((+)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]he...)
Affinity DataKi:  10.8nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50000663((+)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]he...)
Affinity DataKi:  13.7nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50000663((+)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]he...)
Affinity DataKi:  20.4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50000663((+)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]he...)
Affinity DataKi:  24.9nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50000663((+)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]he...)
Affinity DataKi:  27.2nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50000663((+)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]he...)
Affinity DataKi:  53.7nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNischarin(RAT)
University Of Bonn

Curated by PDSP Ki Database
LigandPNGBDBM50000663((+)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]he...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Rattus norvegicus (Rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000663((+)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]he...)
Affinity DataKi:  4.09E+4nMAssay Description:Tested for invitro inhibition of the displacement of [3H]-mazindol from GABA receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000663((+)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]he...)
Affinity DataKi:  5.92E+4nMAssay Description:Tested for invitro inhibition of the displacement of (+)-[3H]-pentazocine from sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000663((+)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]he...)
Affinity DataKi: >1.00E+5nMAssay Description:Tested for invitro inhibition of the displacement of [3H]-FOXY from mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000663((+)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]he...)
Affinity DataKi: >1.00E+5nMAssay Description:Tested for in vitro inhibition of the displacement of [3H]QNB from CNS receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Medical University Of Lublin

Curated by ChEMBL
LigandPNGBDBM50000663((+)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]he...)
Affinity DataIC50:  9nMpH: 6.9Assay Description:Antagonist activity at NR1/2B receptor (unknown origin) expressed in xenopus laevis at pH 6.9 by two electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed