BDBM50068267 (E)-3-(4-Hydroxy-2-methoxy-phenyl)-1-(4-hydroxy-phenyl)-propenone::3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one::CHEMBL141530::Echinatin
SMILES COc1cc(O)ccc1\C=C\C(=O)c1ccc(O)cc1
InChI Key InChIKey=QJKMIJNRNRLQSS-WEVVVXLNSA-N
Data 10 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50068267
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Institute
Curated by ChEMBL
Institute
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant human PTP1B assessed as hydrolysis of p-nitrophenyl phosphate after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of Influenza A H9N2 virus neuraminidase activity after 2 hrs by spectrofluorometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.14E+4nMAssay Description:Inhibition of Influenza A H1N1 virus neuraminidase activity after 2 hrs by spectrofluorometryMore data for this Ligand-Target Pair
Affinity DataIC50: 8.13E+3nMAssay Description:Inhibition of oseltamivir-resistant H1N1 swine influenza virus neuraminidase H274Y mutant activity expressed in HEK293T cells after 2 hrs by spectrof...More data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of TDP1 (unknown origin) expressed in Escherichia coli BL21 (DE3) using 5'-FAM-AGGATCTAAAAGACTT-BHQ-3' as substrate preincubated for 30 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 3.03E+4nMAssay Description:Noncompetitive inhibition of Influenza A H1N1 virus neuraminidase activity by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.99E+4nMAssay Description:Inhibition of Clostridium perfringens neuraminidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.03E+4nMAssay Description:Inhibition of cathepsin L (unknown origin) using Z-FR-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.77E+4nMAssay Description:Inhibition of cathepsin B (unknown origin) using RR-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.24E+3nMAssay Description:Inhibition of wild type H1N1 swine influenza virus neuraminidase activity expressed in HEK293T cells after 2 hrs by spectrofluorometryMore data for this Ligand-Target Pair