BDBM50367123 ETORPHINE::M99

SMILES CCC[C@](C)(O)[C@H]1C[C@]23C=C[C@]1(O)[C@@H]1Oc4c5c(C[C@H]2N(C)CC[C@@]315)ccc4O

InChI Key InChIKey=KBKSVRDSTJRCDJ-LSVYRBPNSA-N

Data  7 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50367123   

TargetMu-type opioid receptor(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50367123(ETORPHINE | M99)
Affinity DataKi:  0.140nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50367123(ETORPHINE | M99)
Affinity DataKi:  0.180nMAssay Description:Binding affinity against Opioid receptor kappa 1 isolated from rat brain membarane was determined using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50367123(ETORPHINE | M99)
Affinity DataKi:  0.260nMAssay Description:Binding affinity against Opioid receptor mu 1 isolated from rat brain membarane was determined using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50367123(ETORPHINE | M99)
Affinity DataKi:  0.270nMAssay Description:Binding affinity against Opioid receptor delta 1 isolated from rat brain membarane was determined using [3H][Ile]-deltorphin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50367123(ETORPHINE | M99)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50367123(ETORPHINE | M99)
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]diprenorphine from mouse delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50367123(ETORPHINE | M99)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]DAMGO from rat mu opioid receptor expressed in CHO cells at 1 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50367123(ETORPHINE | M99)
Affinity DataIC50:  0.140nMAssay Description:Inhibition of [3H]- DAMGO binding to Rat brain Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50367123(ETORPHINE | M99)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of [3H]- U69,593 binding to Guinea pig Opioid receptor kappa 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
University Of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50367123(ETORPHINE | M99)
Affinity DataIC50:  7.40nMAssay Description:Inhibition of [3H]- DADLE binding to Rat brain Opioid receptor delta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed