BDBM50366821 EVODIAMINE

SMILES CN1[C@@H]2N(CCc3c2[nH]c2ccccc32)C(=O)c2ccccc12

InChI Key InChIKey=TXDUTHBFYKGSAH-GOSISDBHSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50366821   

TargetCytochrome P450 1A2(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50366821(EVODIAMINE)
Affinity DataIC50:  1.63E+4nMAssay Description:Inhibition of Cytochrome P450 1A2 enzyme in bacterial membrane expressing human P450sMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50366821(EVODIAMINE)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human PDE5A1 (535-860 residues) expressed in Escherichia coli BL21 incubated for 15 mins using [3H]-cGMP as substrate by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50366821(EVODIAMINE)
Affinity DataIC50:  2.46E+4nMAssay Description:Inhibition of Cytochrome P450 1A1 enzyme in bacterial membrane expressing human P450sMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50366821(EVODIAMINE)
Affinity DataIC50:  690nMAssay Description:Inhibition of Cytochrome P450 1B1 enzyme in bacterial membrane expressing human P450sMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed