BDBM50366821 EVODIAMINE
SMILES CN1[C@@H]2N(CCc3c2[nH]c2ccccc32)C(=O)c2ccccc12
InChI Key InChIKey=TXDUTHBFYKGSAH-GOSISDBHSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50366821
TargetCytochrome P450 1A2(Homo sapiens (Human))
National Research Institute Of Chinese Medicine
Curated by ChEMBL
National Research Institute Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of Cytochrome P450 1A2 enzyme in bacterial membrane expressing human P450sMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sun Yat-Sen University
Curated by ChEMBL
Sun Yat-Sen University
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human PDE5A1 (535-860 residues) expressed in Escherichia coli BL21 incubated for 15 mins using [3H]-cGMP as substrate by liquid scintil...More data for this Ligand-Target Pair
TargetCytochrome P450 1A1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine
Curated by ChEMBL
National Research Institute Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 2.46E+4nMAssay Description:Inhibition of Cytochrome P450 1A1 enzyme in bacterial membrane expressing human P450sMore data for this Ligand-Target Pair
TargetCytochrome P450 1B1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine
Curated by ChEMBL
National Research Institute Of Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 690nMAssay Description:Inhibition of Cytochrome P450 1B1 enzyme in bacterial membrane expressing human P450sMore data for this Ligand-Target Pair