BDBM50216165 1,11-dihydro-1,3,5,11-tetraaza-benzo[a]trindene-4,6-dione::3,11-Dihydro-1,3,5,11-tetraaza-benzo[a]trindene-4,6-dione::CHEMBL240747::granulatimide
SMILES O=C1NC(=O)c2c1c1[nH]cnc1c1[nH]c3ccccc3c21
InChI Key InChIKey=LBTREMHIJGMYQN-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50216165
Affinity DataIC50: 81nMAssay Description:Inhibition of human Chk1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of human Chk1More data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of human Chk1More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataIC50: 740nMAssay Description:Inhibitory activity against Cyclin D1-cyclin-dependent kinase 4 by measuring the phosphorylation of RbINGMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of Chk1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Inhibition of human Chk1More data for this Ligand-Target Pair