BDBM50206160 CHEMBL245621::Halopemide::Halopemide, 8::N-(2-(4-(5-chloro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-4-fluorobenzamide::N-(2-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-4-fluorobenzamide::cid_65490
SMILES Fc1ccc(cc1)C(=O)NCCN1CCC(CC1)n1c2ccc(Cl)cc2[nH]c1=O
InChI Key InChIKey=NBHPRWLFLUBAIE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 50206160
Affinity DataIC50: 220nMT: 2°CAssay Description:PLD in vitro enzymatic assay using phospholipase D1(PLD1).More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of PLD1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 11nMT: 2°CAssay Description:Phopholipase D1(PLD)enzymatic inhibition assay using PLD1.d311More data for this Ligand-Target Pair
Affinity DataEC50: 21nMT: 2°CAssay Description:cell-based assay using human non-small-cell lung cancer cell line, Calu-1More data for this Ligand-Target Pair
Affinity DataEC50: 300nMT: 2°CAssay Description:cell-based assay using HEK293-gfpPLD2 cell lineMore data for this Ligand-Target Pair
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt Specialized Chemistry Center
Curated by PubChem BioAssay
Vanderbilt Specialized Chemistry Center
Curated by PubChem BioAssay
Affinity DataIC50: 280nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt Specialized Chemistry Center
Curated by PubChem BioAssay
Vanderbilt Specialized Chemistry Center
Curated by PubChem BioAssay
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of PLD2More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of human PLD1 in Calu1 cellsMore data for this Ligand-Target Pair
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt Specialized Chemistry Center
Curated by PubChem BioAssay
Vanderbilt Specialized Chemistry Center
Curated by PubChem BioAssay
Affinity DataIC50: 300nMAssay Description:Inhibition of GFP-labelled human PLD2 HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of PLD1 (unknown origin)More data for this Ligand-Target Pair
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt Specialized Chemistry Center
Curated by PubChem BioAssay
Vanderbilt Specialized Chemistry Center
Curated by PubChem BioAssay
Affinity DataIC50: 310nMAssay Description:Inhibition of PLD2 (unknown origin)More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Vanderbilt University Medical Center
Curated by ChEMBL
Vanderbilt University Medical Center
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of dopamine receptor D2 (unknown origin)More data for this Ligand-Target Pair
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt Specialized Chemistry Center
Curated by PubChem BioAssay
Vanderbilt Specialized Chemistry Center
Curated by PubChem BioAssay
Affinity DataIC50: 300nMAssay Description:Inhibition of PLD2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 310nMT: 2°CAssay Description:PLD in vitro enzymatic assay using phospholipase D2(PLD2).More data for this Ligand-Target Pair