BDBM82355 Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Ibotenic acid)::CAS_2552-55-8::CHEMBL284895::Ibotenate::Ibotenic acid::NSC_1233

SMILES NC(C(O)=O)c1cc(=O)[nH]o1

InChI Key InChIKey=IRJCBFDCFXCWGO-UHFFFAOYSA-N

Data  23 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 26 hits for monomerid = 82355   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
Affinity DataKi:  89nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
Affinity DataKi:  1.20E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
Affinity DataKi:  1.90E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate metabotropic receptor 5(PORCINE)
Cnrs Ccipe

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
Affinity DataKi:  1.93E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
Affinity DataKi:  2.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate metabotropic receptor 5(PORCINE)
Cnrs Ccipe

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
Affinity DataKi:  2.87E+3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 6(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Upr Centre

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate metabotropic receptor 1(PORCINE)
Cnrs Ccipe

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
The Royal Danish School Of Pharmacy

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Upr Centre

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
The Royal Danish School Of Pharmacy

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
Affinity DataKi:  1.70E+4nMAssay Description:Agonist potency against cloned metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
Affinity DataKi:  4.30E+4nMAssay Description:Agonist potency against cloned human metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
Affinity DataKi:  1.10E+5nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 2 (mGluR-2).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
Affinity DataKi: >1.00E+6nMAssay Description:Agonist potency against cloned human Metabotropic glutamate receptor 4 (mGluR-4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
The Royal Danish School Of Pharmacy

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
Affinity DataEC50:  4.30E+4nMAssay Description:Compound was evaluated for agonistic activity against mGluR1 alpha metabotropic receptor subtype in rat cortical slice modelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was evaluated for agonistic activity against mGluR4a alpha metabotropic receptor subtype in rat cortical slice modelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
Affinity DataEC50:  1.10E+5nMAssay Description:Compound was evaluated for agonistic activity against mGluR2 alpha metabotropic receptor subtype in rat cortical slice modelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed