BDBM20606 (5R,6S)-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol::(5R,6S)-6-phenyl-5-{4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}-5,6,7,8-tetrahydronaphthalen-2-ol::CHEMBL328190::Lasofoxifene::Oporia
SMILES Oc1ccc2[C@H]([C@H](CCc2c1)c1ccccc1)c1ccc(OCCN2CCCC2)cc1
InChI Key InChIKey=GXESHMAMLJKROZ-IAPPQJPRSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 20606
Affinity DataIC50: 4nM EC50: 3.10nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
Affinity DataIC50: 13nM EC50: 24nMT: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
Affinity DataIC50: 4nM EC50: 3.10nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
Affinity DataIC50: 13nM EC50: 24nMT: 2°CAssay Description:Radioligand binding assay was performed by using 96-well microtiterplates containing ER, 17beta-estradiol, and the test compound to be tested and SPA...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of estradiol binding to estrogen receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Binding affinity for human estrogen receptor alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of binding to recombinant human ERalpha by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of binding to recombinant human ERbeta by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of estradiol binding to estrogen receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Binding affinity for human estrogen receptor betaMore data for this Ligand-Target Pair