BDBM50418089 Limonin
SMILES [H][C@]12O[C@@]11[C@@](C)(CC[C@]3([H])[C@@]45COC(=O)C[C@]4([H])OC(C)(C)[C@]5([H])CC(=O)[C@@]13C)[C@@H](OC2=O)c1ccoc1
InChI Key InChIKey=BEAROWPOUPFNRD-HEZIXOHUSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50418089
Affinity DataKi: 2.32E+4nMAssay Description:Mechanism based inhibition of human cytochrome P450 3A4 measured by (14C)formaldehyde production from (N-methyl-14C)-erythromycinMore data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Central University Of Punjab
Curated by ChEMBL
Central University Of Punjab
Curated by ChEMBL
Affinity DataIC50: 1.91E+4nMAssay Description:Inhibition of P-gp in human Caco2 cells assessed as potentiation of doxorubicin-induced cytotoxicity by measuring reduction in doxorubicin IC50 at 2....More data for this Ligand-Target Pair
Affinity DataIC50: >4.25E+5nMAssay Description:Inhibition of HIV1 RTMore data for this Ligand-Target Pair
Affinity DataIC50: 8.99nMAssay Description:Inhibition of HIV1 3B reverse transcriptase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 4.48nMAssay Description:Inhibition of HIV1 3B reverse transcriptase activity infected in human H9 cells assessed as level of p24 antigenMore data for this Ligand-Target Pair