BDBM81469 CAS_91-80-5::Methapyrilene::NSC_4098

SMILES CN(C)CCN(Cc1cccs1)c1ccccn1

InChI Key InChIKey=HNJJXZKZRAWDPF-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 81469   

TargetHistamine H1 receptor(RAT)
TBA

Curated by PDSP Ki Database
LigandPNGBDBM81469(CAS_91-80-5 | Methapyrilene | NSC_4098)
Affinity DataKi:  4.5nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt export pump(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM81469(CAS_91-80-5 | Methapyrilene | NSC_4098)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human BSEP expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt export pump(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM81469(CAS_91-80-5 | Methapyrilene | NSC_4098)
Affinity DataIC50: >1.00E+6nMAssay Description:Ability to inhibit HMG-CoA reductase (HMGR) by CoA reductase inhibition screen (COR) in ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt export pump(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM81469(CAS_91-80-5 | Methapyrilene | NSC_4098)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of Sprague-Dawley rat Bsep expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate up...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed