BDBM50069792 (2S)-2-[(2S)-2-acetamido-4-methylpentanamido]-N-[(1S)-1-formylpentyl]-4-methylpentanamide::Acetylleucyl-leucyl-norleucinal::CHEMBL304784::Calpain inhibitor I::N-acetylleucylleucylnorleucinal

SMILES CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(C)=O)C=O

InChI Key InChIKey=FMYKJLXRRQTBOR-BZSNNMDCSA-N

Data  2 KI  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50069792   

TargetCathepsin B(Homo sapiens (Human))
The University Of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50069792((2S)-2-[(2S)-2-acetamido-4-methylpentanamido]-N-[(...)
Affinity DataKi:  150nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Sus scrofa (pig))
The University Of Tennessee Health Science Center

Curated by ChEMBL
LigandPNGBDBM50069792((2S)-2-[(2S)-2-acetamido-4-methylpentanamido]-N-[(...)
Affinity DataKi:  190nMAssay Description:Inhibition of pig erythrocyte mu-calpainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Michigan State University

LigandPNGBDBM50069792((2S)-2-[(2S)-2-acetamido-4-methylpentanamido]-N-[(...)
Affinity DataIC50:  8.60E+3nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Michigan State University

LigandPNGBDBM50069792((2S)-2-[(2S)-2-acetamido-4-methylpentanamido]-N-[(...)
Affinity DataIC50:  8.60E+3nMAssay Description:Inhibition of SARS-CoV-2 MProMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Michigan State University

LigandPNGBDBM50069792((2S)-2-[(2S)-2-acetamido-4-methylpentanamido]-N-[(...)
Affinity DataIC50:  8.59E+3nMAssay Description:Inhibition of SARS-CoV-2 MProMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50069792((2S)-2-[(2S)-2-acetamido-4-methylpentanamido]-N-[(...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory concentration against Calpain I activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain small subunit 1/1 catalytic subunit(Homo sapiens (Human))
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50069792((2S)-2-[(2S)-2-acetamido-4-methylpentanamido]-N-[(...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibitory activity against Calpain IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed