BDBM50338973 5,4'-dihydroxy-3,6,7-trimethoxyflavanone::5-Hydroxy-2-(4-hydroxy-phenyl)-3,6,7-trimethoxy-chromen-4-one::CHEMBL165509::penduletin

SMILES COc1cc2oc(-c3ccc(O)cc3)c(OC)c(=O)c2c(O)c1OC

InChI Key InChIKey=YSXFFLGRZJWNFM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50338973   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50338973(5,4'-dihydroxy-3,6,7-trimethoxyflavanone | 5-Hydro...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of BCRP expressed in MDCK cells using Hoechst 33342 stainingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50338973(5,4'-dihydroxy-3,6,7-trimethoxyflavanone | 5-Hydro...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of MDR1 expressed in MDCK cells using rhodamine 123 staining by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50338973(5,4'-dihydroxy-3,6,7-trimethoxyflavanone | 5-Hydro...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of BCRP expressed in MCF-7 MX cells using Hoechst 33342 stainingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed