BDBM12590 (6-aminoacridin-3-yl)amine::MLS003876812::Proflavin::Proflavine::SMR002533346::acridine-3,6-diamine::cid_7099
SMILES Nc1ccc2cc3ccc(N)cc3nc2c1
InChI Key InChIKey=WDVSHHCDHLJJJR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 12590
Affinity DataIC50: 1.20E+4nMpH: 8.0 T: 2°CAssay Description:The cleavage of the substrate was followed by monitoring the change in fluorescence at 460 nm (excitation at 365 nm) for 25 min at room temperature o...More data for this Ligand-Target Pair
TargetPC4 and SFRS1-interacting protein(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 4.34E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: Ohio State University Assay Provider: Mam...More data for this Ligand-Target Pair
TargetPC4 and SFRS1-interacting protein(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 4.46E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: Ohio State University Assay Provider: Mam...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Southern Research Institute
Curated by PubChem BioAssay
Southern Research Institute
Curated by PubChem BioAssay
Affinity DataIC50: 1.46E+3nMAssay Description:Inhibition of SARS-CoV-2 papain-like protease using ISG15-AMC as substrateMore data for this Ligand-Target Pair
Affinity DataKd: 1.40E+5nMAssay Description:Binding affinity to birch major pollen allergen Bet v 1-A assessed as binding constant at 1H-6 resonance by (1)H relaxation dispersion NMR spectrosco...More data for this Ligand-Target Pair
Affinity DataIC50: 830nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of SARS-CoV-2 papain-like protease using RLRGG-AMC as substrateMore data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Southern Research Institute
Curated by PubChem BioAssay
Southern Research Institute
Curated by PubChem BioAssay