BDBM50391000 CB-01-11::RIFAMYCIN
SMILES CO[C@H]1\C=C\O[C@@]2(C)Oc3c(C2=O)c2c(O)cc(NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)c(O)c2c(O)c3C
InChI Key InChIKey=HJYYPODYNSCCOU-ODRIEIDWSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 20 hits for monomerid = 50391000
TargetSolute carrier organic anion transporter family member 1B1(Homo sapiens (Human))
University Hospital
Curated by ChEMBL
University Hospital
Curated by ChEMBL
Affinity DataKi: 2.00E+3nMAssay Description:TP_TRANSPORTER: inhibition of BSP uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
TargetSolute carrier organic anion transporter family member 2B1(Homo sapiens (Human))
University Hospital
Curated by ChEMBL
University Hospital
Curated by ChEMBL
Affinity DataKi: 3.00E+3nMAssay Description:TP_TRANSPORTER: inhibition of BSP uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
TargetSolute carrier organic anion transporter family member 1B3(Homo sapiens (Human))
University Hospital
Curated by ChEMBL
University Hospital
Curated by ChEMBL
Affinity DataKi: 3.00E+3nMAssay Description:TP_TRANSPORTER: inhibition of BSP uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
Affinity DataKi: 3.80E+3nMAssay Description:TP_TRANSPORTER: inhibition of Taurocholate uptake in membrane vesicles from Bsep-expressing Sf9 cellsMore data for this Ligand-Target Pair
TargetSolute carrier organic anion transporter family member 1A1(Rattus norvegicus)
University Of Zurich
Curated by ChEMBL
University Of Zurich
Curated by ChEMBL
Affinity DataKi: 6.60E+3nMAssay Description:TP_TRANSPORTER: inhibition of E217betaG uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
TargetSolute carrier organic anion transporter family member 1A4(Rattus norvegicus)
University Of Zurich
Curated by ChEMBL
University Of Zurich
Curated by ChEMBL
Affinity DataKi: 7.30E+3nMAssay Description:TP_TRANSPORTER: inhibition of E217betaG uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
TargetSolute carrier organic anion transporter family member 1A2(Homo sapiens (Human))
University Hospital
Curated by ChEMBL
University Hospital
Curated by ChEMBL
Affinity DataKi: 1.10E+4nMAssay Description:TP_TRANSPORTER: inhibition of BSP uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
Affinity DataKi: 3.10E+4nMAssay Description:TP_TRANSPORTER: inhibition of Taurocholate uptake(Rifampicin SV 30uM, 50 % of control) in membrane vesicles prepared from High Five cells infected wi...More data for this Ligand-Target Pair
Affinity DataIC50: 2.07E+5nMAssay Description:TP_TRANSPORTER: increase in bodipy intracellular accumulation (Bodipy: 0.2 uM) in SK-E2 cells (expressing BSEP)More data for this Ligand-Target Pair
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell membrane vesicles assessed as reduction in ATP or AMP-dependent [3H]-...More data for this Ligand-Target Pair
Affinity DataKd: 1.00E+6nMAssay Description:Binding affinity to 6His-tagged human BCL6 BTB domain (7 to 128 amino acid residues) expressed in Escherichia coli Rosetta (DE3) after 1 min by fluor...More data for this Ligand-Target Pair
Affinity DataIC50: 1.22E+4nMAssay Description:TP_TRANSPORTER: increase in dihydrofluorescein intracellular accumulation (dihydrofluorescein: 1 uM) in SK-E2 cells (expressing BSEP)More data for this Ligand-Target Pair
TargetSolute carrier organic anion transporter family member 1B1(Homo sapiens (Human))
University Hospital
Curated by ChEMBL
University Hospital
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:TP_TRANSPORTER: inhibition of estradiol-17beta-glucuronide uptake(estradiol-17beta-glucuronide:0.02uM) in OATP1B1-expressing HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of human BSEP expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of Sprague-Dawley rat Bsep expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate up...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMT: 2°CAssay Description:Fluorescence-detected RNAP inhibition assays in Tables 1 and 4 were performed using a DNA fragment containing the lacUV5 promoter as a template and t...More data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+4nMT: 2°CAssay Description:Fluorescence-detected RNAP inhibition assays in Tables 1 and 4 were performed using a DNA fragment containing the lacUV5 promoter as a template and t...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMT: 2°CAssay Description:Fluorescence-detected RNAP inhibition assays in Tables 1 and 4 were performed using a DNA fragment containing the lacUV5 promoter as a template and t...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMT: 2°CAssay Description:Fluorescence-detected RNAP inhibition assays in Tables 1 and 4 were performed using a DNA fragment containing the lacUV5 promoter as a template and t...More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+4nMT: 2°CAssay Description:Fluorescence-detected RNAP inhibition assays in Tables 1 and 4 were performed using a DNA fragment containing the lacUV5 promoter as a template and t...More data for this Ligand-Target Pair