BDBM50071484 CHEMBL308148::N-[(R)-4-(4-Acetylamino-4-phenyl-piperidin-1-yl)-2-(3,4-dichloro-phenyl)-butyl]-N-methyl-benzamide::N-[(S)-4-(4-Acetylamino-4-phenyl-piperidin-1-yl)-2-(3,4-dichloro-phenyl)-butyl]-N-methyl-benzamide::Saredutant
SMILES CN(C[C@@H](CCN1CCC(CC1)(NC(C)=O)c1ccccc1)c1ccc(Cl)c(Cl)c1)C(=O)c1ccccc1
InChI Key InChIKey=PGKXDIMONUAMFR-AREMUKBSSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50071484
Affinity DataKi: 0.5nMAssay Description:Inhibition of [125I]-NKA binding to neurokinin NK2 receptor from rat duodenum membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Binding affinity against bovine Tachykinin receptor 2More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Binding affinity towards Tachykinin receptor 2 in CHO cells using [3H]-neurokinin A as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.510nMAssay Description:Tested in vitro to inhibit the binding of [125I]-NKA to its receptor in rat duodenum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:The compound was evaluated for the inhibition of [125I]-NKA binding to neurokinin NK2 receptor from hamster urinary bladder membranesMore data for this Ligand-Target Pair
Affinity DataKi: 945nMAssay Description:The compound was evaluated for the inhibition of [125I]-NKA binding to Tachykinin receptor 2 from rat duodenum membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:Inhibition of cloned human NK2 (Neurokinin 2) receptor, stably expressed in chinese hamster ovary (CHO) cells was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 208nMAssay Description:NK3 IC50 determined using [125I]-Bolton Hunter labeled eledoisin at NK3 receptors from guinea pig cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 0.440nMAssay Description:Binding affinity against human NK2 receptors from HSKR-1 cells using [125I]-Iodohistidyl NKAMore data for this Ligand-Target Pair
Affinity DataIC50: 593nMAssay Description:Binding affinity against Neurokinin 1(NK1) receptor from human IM-9 cells using [I]-Bolton Hunter labeled SPMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of cloned human NK1 (Neurokinin 1) receptor, stably expressed in chinese hamster ovary (CHO) cells was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Binding affinity was determined against human NK2 receptor in CHO cells using [125I]-neurokinin A as radioligandMore data for this Ligand-Target Pair