BDBM50338975 2-(3,4-dimethoxyphenyl)-5,6,7-trimethoxy-4H-chromen-4-one::3',4',5,6,7-pentamethoxy flavone::5,6,7,3',4' -pentamethoxyflavone::CHEMBL226507::Sinensetin (3)::sinensetin

SMILES COc1ccc(cc1OC)-c1cc(=O)c2c(OC)c(OC)c(OC)cc2o1

InChI Key InChIKey=LKMNXYDUQXAUCZ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50338975   

TargetAurora kinase B(Homo sapiens (Human))
Konkuk University

LigandPNGBDBM50338975(2-(3,4-dimethoxyphenyl)-5,6,7-trimethoxy-4H-chrome...)
Affinity DataIC50:  5.31E+3nMAssay Description:The kinase assay was performed using the EMD Millipore KinaseProfiler service assay protocol. Aurora B kinase was supplied by EMD Millipore Corp. The...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50338975(2-(3,4-dimethoxyphenyl)-5,6,7-trimethoxy-4H-chrome...)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of BCRP expressed in MCF-7 MX cells using Hoechst 33342 stainingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Chosun University

Curated by ChEMBL
LigandPNGBDBM50338975(2-(3,4-dimethoxyphenyl)-5,6,7-trimethoxy-4H-chrome...)
Affinity DataIC50:  3.20E+3nMAssay Description:TP_TRANSPORTER: drug resistance (vincristine) in AML-2/D100 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Chosun University

Curated by ChEMBL
LigandPNGBDBM50338975(2-(3,4-dimethoxyphenyl)-5,6,7-trimethoxy-4H-chrome...)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of MDR1 expressed in MDCK cells using rhodamine 123 staining by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50338975(2-(3,4-dimethoxyphenyl)-5,6,7-trimethoxy-4H-chrome...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of BCRP expressed in MDCK cells using Hoechst 33342 stainingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed